A Multi-scale Computational Platform to Mechanistically Assess the Effect of Genetic Variation on Drug Responses in Human Erythrocyte Metabolism

por Mih, Nathan, Brunk, Elizabeth, Bordbar, Aarash, Palsson, Bernhard O.
Publicado 2016

A Mechanochemical Switch to Control Radical Intermediates

por Brunk, Elizabeth, Kellett, Whitney F., Richards, Nigel G. J., Rothlisberger, Ursula
Publicado 2014

Advances in the Management of Early-Stage Triple-Negative Breast Cancer

por Bhardwaj, Prarthna V., Wang, Yue, Brunk, Elizabeth, Spanheimer, Philip M., Abdou, Yara G.
Publicado 2023

Growth Adaptation of gnd and sdhCB Escherichia coli Deletion Strains Diverges From a Similar Initial Perturbation of the Transcriptome

por McCloskey, Douglas, Xu, Sibei, Sandberg, Troy E., Brunk, Elizabeth, Hefner, Ying, Szubin, Richard, Feist, Adam M., Palsson, Bernhard O.
Publicado 2018

Evolution of gene knockout strains of E. coli reveal regulatory architectures governed by metabolism

por McCloskey, Douglas, Xu, Sibei, Sandberg, Troy E., Brunk, Elizabeth, Hefner, Ying, Szubin, Richard, Feist, Adam M., Palsson, Bernhard O.
Publicado 2018

Systems biology of the structural proteome

por Brunk, Elizabeth, Mih, Nathan, Monk, Jonathan, Zhang, Zhen, O’Brien, Edward J., Bliven, Spencer E., Chen, Ke, Chang, Roger L., Bourne, Philip E., Palsson, Bernhard O.
Publicado 2016

Multi-omic data integration enables discovery of hidden biological regularities

por Ebrahim, Ali, Brunk, Elizabeth, Tan, Justin, O'Brien, Edward J., Kim, Donghyuk, Szubin, Richard, Lerman, Joshua A., Lechner, Anna, Sastry, Anand, Bordbar, Aarash, Feist, Adam M., Palsson, Bernhard O.
Publicado 2016

Model-driven discovery of synergistic inhibitors against E. coli and S. enterica serovar Typhimurium targeting a novel synthetic lethal pair, aldA and prpC

por Aziz, Ramy K., Khaw, Valerie L., Monk, Jonathan M., Brunk, Elizabeth, Lewis, Robert, Loh, Suh I., Mishra, Arti, Nagle, Amrita A., Satyanarayana, Chitkala, Dhakshinamoorthy, Saravanakumar, Luche, Michele, Kitchen, Douglas B., Andrews, Kathleen A., Palsson, Bernhard Ø., Charusanti, Pep
Publicado 2015

Recon3D: A Resource Enabling A Three-Dimensional View of Gene Variation in Human Metabolism

por Brunk, Elizabeth, Sahoo, Swagatika, Zielinski, Daniel C., Altunkaya, Ali, Dräger, Andreas, Mih, Nathan, Gatto, Francesco, Nilsson, Avlant, Gonzalez, German Andres Preciat, Aurich, Maike Kathrin, Prlić, Andreas, Sastry, Anand, Danielsdottir, Anna D., Heinken, Almut, Noronha, Alberto, Rose, Peter W., Burley, Stephen K., Fleming, Ronan M.T., Nielsen, Jens, Thiele, Ines, Palsson, Bernhard O.
Publicado 2018

Mapping genetic variations to three-dimensional protein structures to enhance variant interpretation: a proposed framework

por Glusman, Gustavo, Rose, Peter W., Prlić, Andreas, Dougherty, Jennifer, Duarte, José M., Hoffman, Andrew S., Barton, Geoffrey J., Bendixen, Emøke, Bergquist, Timothy, Bock, Christian, Brunk, Elizabeth, Buljan, Marija, Burley, Stephen K., Cai, Binghuang, Carter, Hannah, Gao, JianJiong, Godzik, Adam, Heuer, Michael, Hicks, Michael, Hrabe, Thomas, Karchin, Rachel, Leman, Julia Koehler, Lane, Lydie, Masica, David L., Mooney, Sean D., Moult, John, Omenn, Gilbert S., Pearl, Frances, Pejaver, Vikas, Reynolds, Sheila M., Rokem, Ariel, Schwede, Torsten, Song, Sicheng, Tilgner, Hagen, Valasatava, Yana, Zhang, Yang, Deutsch, Eric W.
Publicado 2017