Time to inclusion in clinical guidance documents for non-oncological orphan drugs and biologics with expedited FDA designations: a retrospective survival analysis

por Rodriguez, Ryan, Brunner, Rachel, Spencer, Samantha, Qato, Dima M
Publicado 2021

Asxl2(−/−) Mice Exhibit De Novo Cardiomyocyte Production during Adulthood

por Brunner, Rachel, Lai, Hsiao-Lei, Deliu, Zane, Melman, Elan, Geenen, David L., Wang, Q. Tian
Publicado 2016

Incorporating human exposure information in a weight of evidence approach to inform design of repeated dose animal studies

por Lowe, Kelly, Dawson, Jeffrey, Phillips, Katherine, Minucci, Jeffrey, Wambaugh, John F., Qian, Hua, Ramanarayanan, Tharacad, Egeghy, Peter, Ingle, Brandall, Brunner, Rachel, Mendez, Elizabeth, Embry, Michelle, Tan, Yu-Mei
Publicado 2021

Opportunities and challenges related to saturation of toxicokinetic processes: Implications for risk assessment

por Tan, Yu-Mei, Barton, Hugh A., Boobis, Alan, Brunner, Rachel, Clewell, Harvey, Cope, Rhian, Dawson, Jeffrey, Domoradzki, Jeanne, Egeghy, Peter, Gulati, Pankaj, Ingle, Brandall, Kleinstreuer, Nicole, Lowe, Kelly, Lowit, Anna, Mendez, Elizabeth, Miller, David, Minucci, Jeffrey, Nguyen, James, Paini, Alicia, Perron, Monique, Phillips, Katherine, Qian, Hua, Ramanarayanan, Tharacad, Sewell, Fiona, Villanueva, Philip, Wambaugh, John, Embry, Michelle
Publicado 2021