Evaluating CRISPR-based prime editing for cancer modeling and CFTR repair in organoids

por Geurts, Maarten H, de Poel, Eyleen, Pleguezuelos-Manzano, Cayetano, Oka, Rurika, Carrillo, Léo, Andersson-Rolf, Amanda, Boretto, Matteo, Brunsveld, Jesse E, van Boxtel, Ruben, Beekman, Jeffrey M, Clevers, Hans
Publicado 2021

High-throughput functional assay in cystic fibrosis patient-derived organoids allows drug repurposing

por Spelier, Sacha, de Poel, Eyleen, Ithakisiou, Georgia N., Suen, Sylvia W.F., Hagemeijer, Marne C., Muilwijk, Danya, Vonk, Annelotte M., Brunsveld, Jesse E., Kruisselbrink, Evelien, van der Ent, Cornelis K., Beekman, Jeffrey M.
Publicado 2023

Exploring intrinsic variability between cultured nasal and bronchial epithelia in cystic fibrosis

por Rodenburg, Lisa W., Metzemaekers, Mieke, van der Windt, Isabelle S., Smits, Shannon M. A., den Hertog-Oosterhoff, Loes A., Kruisselbrink, Evelien, Brunsveld, Jesse E., Michel, Sabine, de Winter-de Groot, Karin M., van der Ent, Cornelis K., Stadhouders, Ralph, Beekman, Jeffrey M., Amatngalim, Gimano D.
Publicado 2023

Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia

por Amatngalim, Gimano D, Rodenburg, Lisa W, Aalbers, Bente L, Raeven, Henriette HM, Aarts, Ellen M, Sarhane, Dounia, Spelier, Sacha, Lefferts, Juliet W, Silva, Iris AL, Nijenhuis, Wilco, Vrendenbarg, Sacha, Kruisselbrink, Evelien, Brunsveld, Jesse E, van Drunen, Cornelis M, Michel, Sabine, de Winter-de Groot, Karin M, Heijerman, Harry G, Kapitein, Lukas C, Amaral, Magarida D, van der Ent, Cornelis K, Beekman, Jeffrey M
Publicado 2022

Forskolin-induced organoid swelling is associated with long-term cystic fibrosis disease progression

por Muilwijk, Danya, de Poel, Eyleen, van Mourik, Peter, Suen, Sylvia W.F., Vonk, Annelotte M., Brunsveld, Jesse E., Kruisselbrink, Evelien, Oppelaar, Hugo, Hagemeijer, Marne C., Berkers, Gitte, de Winter-de Groot, Karin M., Heida-Michel, Sabine, Jans, Stephan R., van Panhuis, Hannah, van der Eerden, Menno M., van der Meer, Renske, Roukema, Jolt, Dompeling, Edward, Weersink, Els J.M., Koppelman, Gerard H., Vries, Robert, Zomer-van Ommen, Domenique D., Eijkemans, Marinus J.C., van der Ent, Cornelis K., Beekman, Jeffrey M.
Publicado 2022