The fibrotic and immune microenvironments as targetable drivers of metastasis

por Boulter, Luke, Bullock, Esme, Mabruk, Zeanap, Brunton, Valerie G.
Publicado 2020

E7080, a multi-targeted tyrosine kinase inhibitor suppresses tumor cell migration and invasion

por Glen, Hilary, Mason, Susan, Patel, Hitesh, Macleod, Kenneth, Brunton, Valerie G
Publicado 2011

Mouse models of metastasis: progress and prospects

por Gómez-Cuadrado, Laura, Tracey, Natasha, Ma, Ruoyu, Qian, Binzhi, Brunton, Valerie G.
Publicado 2017

Imaging drug uptake by bioorthogonal stimulated Raman scattering microscopy

por Tipping, William J., Lee, Martin, Serrels, Alan, Brunton, Valerie G., Hulme, Alison N.
Publicado 2017

FAK Deletion Promotes p53-Mediated Induction of p21, DNA-Damage Responses and Radio-Resistance in Advanced Squamous Cancer Cells

por Graham, Kathryn, Moran-Jones, Kim, Sansom, Owen J., Brunton, Valerie G., Frame, Margaret C.
Publicado 2011

Development of Potent Inhibitors of Receptor Tyrosine Kinases by Ligand-Based Drug Design and Target-Biased Phenotypic Screening

por Myers, Samuel H., Temps, Carolin, Houston, Douglas R., Brunton, Valerie G., Unciti-Broceta, Asier
Publicado 2018

Kindlin1 regulates microtubule function to ensure normal mitosis

por Patel, Hitesh, Stavrou, Ifigeneia, Shrestha, Roshan L., Draviam, Viji, Frame, Margaret C., Brunton, Valerie G.
Publicado 2016

Detection of Estrogen Receptor Alpha and Assessment of Fulvestrant Activity in MCF-7 Tumor Spheroids Using Microfluidics and SERS

por Kapara, Anastasia, Findlay Paterson, Karla A., Brunton, Valerie G., Graham, Duncan, Zagnoni, Michele, Faulds, Karen
Publicado 2021

Development of a fluorescence-based cellular apoptosis reporter

por Balderstone, Lucy A, Dawson, John C, Welman, Arkadiusz, Serrels, Alan, Wedge, Stephen R, Brunton, Valerie G
Publicado 2019

Raman Imaging of Nanocarriers for Drug Delivery

por Vanden-Hehir, Sally, Tipping, William J., Lee, Martin, Brunton, Valerie G., Williams, Anna, Hulme, Alison N.
Publicado 2019

HO-1 drives autophagy as a mechanism of resistance against HER2-targeted therapies

por Tracey, Natasha, Creedon, Helen, Kemp, Alain J., Culley, Jayne, Muir, Morwenna, Klinowska, Teresa, Brunton, Valerie G.
Publicado 2019

Utilizing Stimulated Raman Scattering Microscopy To Study Intracellular Distribution of Label-Free Ponatinib in Live Cells

por Sepp, Kristel, Lee, Martin, Bluntzer, Marie T. J., Helgason, G. Vignir, Hulme, Alison N., Brunton, Valerie G.
Publicado 2019

Kindlin-1 regulates IL-6 secretion and modulates the immune environment in breast cancer models

por Webb, Emily R, Dodd, Georgia L, Noskova, Michaela, Bullock, Esme, Muir, Morwenna, Frame, Margaret C, Serrels, Alan, Brunton, Valerie G
Publicado 2023

Live Cell in Vitro and in Vivo Imaging Applications: Accelerating Drug Discovery

por Isherwood, Beverley, Timpson, Paul, McGhee, Ewan J, Anderson, Kurt I, Canel, Marta, Serrels, Alan, Brunton, Valerie G, Carragher, Neil O
Publicado 2011

Alkyne-Tagged PLGA Allows Direct Visualization of Nanoparticles In Vitro and Ex Vivo by Stimulated Raman Scattering Microscopy

por Vanden-Hehir, Sally, Cairns, Stefan A., Lee, Martin, Zoupi, Lida, Shaver, Michael P., Brunton, Valerie G., Williams, Anna, Hulme, Alison N.
Publicado 2019

Diversity of Matriptase Expression Level and Function in Breast Cancer

por Welman, Arkadiusz, Sproul, Duncan, Mullen, Peter, Muir, Morwenna, Kinnaird, Andrew R., Harrison, David J., Faratian, Dana, Brunton, Valerie G., Frame, Margaret C.
Publicado 2012

Pathway profiling of a novel SRC inhibitor, AZD0424, in combination with MEK inhibitors for cancer treatment

por Dawson, John C., Munro, Alison, Macleod, Kenneth, Muir, Morwenna, Timpson, Paul, Williams, Robert J., Frame, Margaret, Brunton, Valerie G., Carragher, Neil O.
Publicado 2021

Use of a genetically engineered mouse model as a preclinical tool for HER2 breast cancer

por Creedon, Helen, Balderstone, Lucy A., Muir, Morwenna, Balla, Jozef, Gomez-Cuadrado, Laura, Tracey, Natasha, Loane, Joseph, Klinowska, Teresa, Muller, William J., Brunton, Valerie G.
Publicado 2016

N-alkynyl derivatives of 5-fluorouracil: susceptibility to palladium-mediated dealkylation and toxigenicity in cancer cell culture

por Weiss, Jason T., Fraser, Craig, Rubio-Ruiz, Belén, Myers, Samuel H., Crispin, Richard, Dawson, John C., Brunton, Valerie G., Patton, E. Elizabeth, Carragher, Neil O., Unciti-Broceta, Asier
Publicado 2014

Atlas of Lobular Breast Cancer Models: Challenges and Strategic Directions

por Sflomos, George, Schipper, Koen, Koorman, Thijs, Fitzpatrick, Amanda, Oesterreich, Steffi, Lee, Adrian V., Jonkers, Jos, Brunton, Valerie G., Christgen, Matthias, Isacke, Clare, Derksen, Patrick W. B., Brisken, Cathrin
Publicado 2021