The ARF GTPase regulatory network in collective invasion and metastasis

por Nikolatou, Konstantina, Bryant, David M., Sandilands, Emma
Publicado 2023

Par3 integrates Tiam1 and phosphatidylinositol 3-kinase signaling to change apical membrane identity

por Ruch, Travis R., Bryant, David M., Mostov, Keith E., Engel, Joanne N.
Publicado 2017

A functional genomics screen reveals a strong synergistic effect between docetaxel and the mitotic gene DLGAP5 that is mediated by the androgen receptor

por Hewit, Kay, Sandilands, Emma, Martinez, Rafael Sanchez, James, Daniel, Leung, Hing Y., Bryant, David M., Shanks, Emma, Markert, Elke K.
Publicado 2018

The phospholipid PI(3,4)P(2) is an apical identity determinant

por Román-Fernández, Álvaro, Roignot, Julie, Sandilands, Emma, Nacke, Marisa, Mansour, Mohammed A., McGarry, Lynn, Shanks, Emma, Mostov, Keith E., Bryant, David M.
Publicado 2018

The MSP‐RON axis stimulates cancer cell growth in models of triple negative breast cancer

por Millar, Rhona, Kilbey, Anna, Remak, Sarah‐Jane, Severson, Tesa M., Dhayade, Sandeep, Sandilands, Emma, Foster, Kyla, Bryant, David M., Blyth, Karen, Coffelt, Seth B.
Publicado 2020

RAL GTPases mediate EGFR-driven intestinal stem cell proliferation and tumourigenesis

por Nászai, Máté, Bellec, Karen, Yu, Yachuan, Román-Fernández, Alvaro, Sandilands, Emma, Johansson, Joel, Campbell, Andrew D, Norman, Jim C, Sansom, Owen J, Bryant, David M, Cordero, Julia B
Publicado 2021

The small GTPase ARF3 controls invasion modality and metastasis by regulating N-cadherin levels

por Sandilands, Emma, Freckmann, Eva C., Cumming, Erin M., Román-Fernández, Alvaro, McGarry, Lynn, Anand, Jayanthi, Galbraith, Laura, Mason, Susan, Patel, Rachana, Nixon, Colin, Cartwright, Jared, Leung, Hing Y., Blyth, Karen, Bryant, David M.
Publicado 2023

Synaptotagmin-Like Proteins Control Formation of a Single Apical Membrane Domain in Epithelial Cells

por Gálvez-Santisteban, Manuel, Rodriguez-Fraticelli, Alejo E., Bryant, David M., Vergarajauregui, Silvia, Yasuda, Takao, Bañón-Rodríguez, Inmaculada, Bernascone, Ilenia, Datta, Anirban, Spivak, Natalie, Young, Kitty, Slim, Christiaan L., Brakeman, Paul R., Fukuda, Mitsunori, Mostov, Keith E., Martín-Belmonte, Fernando
Publicado 2012

PTEN deficiency exposes a requirement for an ARF GTPase module for integrin‐dependent invasion in ovarian cancer

por Nikolatou, Konstantina, Sandilands, Emma, Román‐Fernández, Alvaro, Cumming, Erin M, Freckmann, Eva, Lilla, Sergio, Buetow, Lori, McGarry, Lynn, Neilson, Matthew, Shaw, Robin, Strachan, David, Miller, Crispin, Huang, Danny T, McNeish, Iain A, Norman, James C, Zanivan, Sara, Bryant, David M
Publicado 2023

Traject3d allows label-free identification of distinct co-occurring phenotypes within 3D culture by live imaging

por Freckmann, Eva C., Sandilands, Emma, Cumming, Erin, Neilson, Matthew, Román-Fernández, Alvaro, Nikolatou, Konstantina, Nacke, Marisa, Lannagan, Tamsin R. M., Hedley, Ann, Strachan, David, Salji, Mark, Morton, Jennifer P., McGarry, Lynn, Leung, Hing Y., Sansom, Owen J., Miller, Crispin J., Bryant, David M.
Publicado 2022

An ARF GTPase module promoting invasion and metastasis through regulating phosphoinositide metabolism

por Nacke, Marisa, Sandilands, Emma, Nikolatou, Konstantina, Román-Fernández, Álvaro, Mason, Susan, Patel, Rachana, Lilla, Sergio, Yelland, Tamas, Galbraith, Laura C. A., Freckmann, Eva C., McGarry, Lynn, Morton, Jennifer P., Shanks, Emma, Leung, Hing Y., Markert, Elke, Ismail, Shehab, Zanivan, Sara, Blyth, Karen, Bryant, David M.
Publicado 2021

Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function

por Román-Fernández, Alvaro, Mansour, Mohammed A., Kugeratski, Fernanda G., Anand, Jayanthi, Sandilands, Emma, Galbraith, Laura, Rakovic, Kai, Freckmann, Eva C., Cumming, Erin M., Park, Ji, Nikolatou, Konstantina, Lilla, Sergio, Shaw, Robin, Strachan, David, Mason, Susan, Patel, Rachana, McGarry, Lynn, Katoch, Archana, Campbell, Kirsteen J., Nixon, Colin, Miller, Crispin J., Leung, Hing Y., Le Quesne, John, Norman, James C., Zanivan, Sara, Blyth, Karen, Bryant, David M.
Publicado 2023

Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium

por Reid, Steven E, Kay, Emily J, Neilson, Lisa J, Henze, Anne‐Theres, Serneels, Jens, McGhee, Ewan J, Dhayade, Sandeep, Nixon, Colin, Mackey, John BG, Santi, Alice, Swaminathan, Karthic, Athineos, Dimitris, Papalazarou, Vasileios, Patella, Francesca, Román‐Fernández, Álvaro, ElMaghloob, Yasmin, Hernandez‐Fernaud, Juan Ramon, Adams, Ralf H, Ismail, Shehab, Bryant, David M, Salmeron‐Sanchez, Manuel, Machesky, Laura M, Carlin, Leo M, Blyth, Karen, Mazzone, Massimiliano, Zanivan, Sara
Publicado 2017