Structural characterization of human heparanase reveals insights into substrate recognition

por Wu, Liang, Viola, Cristina M., Brzozowski, Andrzej M., Davies, Gideon J.
Publicado 2015

Structural conservation of insulin/IGF signalling axis at the insulin receptors level in Drosophila and humans

por Viola, Cristina M., Frittmann, Orsolya, Jenkins, Huw T., Shafi, Talha, De Meyts, Pierre, Brzozowski, Andrzej M.
Publicado 2023

Structural and Functional Study of the GlnB22-Insulin Mutant Responsible for Maturity-Onset Diabetes of the Young

por Křížková, Květoslava, Veverka, Václav, Maletínská, Lenka, Hexnerová, Rozálie, Brzozowski, Andrzej M., Jiráček, Jiří, Žáková, Lenka
Publicado 2014

Cross-Linking/Mass Spectrometry Uncovers Details of Insulin-Like Growth Factor Interaction With Insect Insulin Binding Protein Imp-L2

por Pompach, Petr, Viola, Cristina M., Radosavljević, Jelena, Lin, Jingjing, Jiráček, Jiří, Brzozowski, Andrzej M., Selicharová, Irena
Publicado 2019

Human insulin analogues modified at the B26 site reveal a hormone conformation that is undetected in the receptor complex

por Žáková, Lenka, Kletvíková, Emília, Lepšík, Martin, Collinsová, Michaela, Watson, Christopher J., Turkenburg, Johan P., Jiráček, Jiří, Brzozowski, Andrzej M.
Publicado 2014

The crystal structure of superoxide dismutase from Plasmodium falciparum

por Boucher, Ian W, Brzozowski, Andrzej M, Brannigan, James A, Schnick, Claudia, Smith, Derek J, Kyes, Sue A, Wilkinson, Anthony J
Publicado 2006

Recombinant polymorphic membrane protein D in combination with a novel, second-generation lipid adjuvant protects against intra-vaginal Chlamydia trachomatis infection in mice

por Paes, Wayne, Brown, Naj, Brzozowski, Andrzej M., Coler, Rhea, Reed, Steve, Carter, Darrick, Bland, Martin, Kaye, Paul M., Lacey, Charles J.N.
Publicado 2016

Insight into the Structural and Biological Relevance of the T/R Transition of the N-Terminus of the B-Chain in Human Insulin

por Kosinová, Lucie, Veverka, Václav, Novotná, Pavlína, Collinsová, Michaela, Urbanová, Marie, Moody, Nicholas R., Turkenburg, Johan P., Jiráček, Jiří, Brzozowski, Andrzej M., Žáková, Lenka
Publicado 2014

Structural and biochemical characterization of a mitochondrial peroxiredoxin from Plasmodium falciparum

por Boucher, Ian W, McMillan, Paul J, Gabrielsen, Mads, Akerman, Susan E, Brannigan, James A, Schnick, Claudia, Brzozowski, Andrzej M, Wilkinson, Anthony J, Müller, Sylke
Publicado 2006

Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules

por Palivec, Vladimír, Viola, Cristina M., Kozak, Mateusz, Ganderton, Timothy R., Křížková, Květoslava, Turkenburg, Johan P., Halušková, Petra, Žáková, Lenka, Jiráček, Jiří, Jungwirth, Pavel, Brzozowski, Andrzej M.
Publicado 2017

N-Myristoyltransferase from Leishmania donovani: Structural and Functional Characterisation of a Potential Drug Target for Visceral Leishmaniasis

por Brannigan, James A., Smith, Barbara A., Yu, Zhiyong, Brzozowski, Andrzej M., Hodgkinson, Michael R., Maroof, Asher, Price, Helen P., Meier, Franziska, Leatherbarrow, Robin J., Tate, Edward W., Smith, Deborah F., Wilkinson, Anthony J.
Publicado 2010

Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones

por Roed, Nikolaj Kulahin, Viola, Cristina M., Kristensen, Ole, Schluckebier, Gerd, Norrman, Mathias, Sajid, Waseem, Wade, John D., Andersen, Asser Sloth, Kristensen, Claus, Ganderton, Timothy R., Turkenburg, Johan P., De Meyts, Pierre, Brzozowski, Andrzej M.
Publicado 2018

Rational steering of insulin binding specificity by intra-chain chemical crosslinking

por Viková, Jitka, Collinsová, Michaela, Kletvíková, Emília, Buděšínský, Miloš, Kaplan, Vojtěch, Žáková, Lenka, Veverka, Václav, Hexnerová, Rozálie, Aviñó, Roberto J. Tarazona, Straková, Jana, Selicharová, Irena, Vaněk, Václav, Wright, Daniel W., Watson, Christopher J., Turkenburg, Johan P., Brzozowski, Andrzej M., Jiráček, Jiří
Publicado 2016