A Rationale for Drug Design Provided by Co-Crystal Structure of IC261 in Complex with Tubulin

por Xian, Jinghong, Bu, Faqian, Wang, Yuxi, Long, Fangyi, Zhang, Zhixiong, Wu, Chengyong, Tao, Yiran, Wang, Ting, Wang, Guan
Publicado 2021

Rational design and crystallographic analysis of novel isoform-selective TRKA inhibitors for cancer therapy

por Wang, Guan, Wu, Yongya, Wu, Chengyong, Shuai, Wen, Jiang, Tingting, Wang, Aoxue, Bu, Faqian, Sun, Qiu, Ouyang, Liang
Publicado 2023

Development of small molecule extracellular signal-regulated kinases (ERKs) inhibitors for cancer therapy

por Pan, Xiaoli, Pei, Junping, Wang, Aoxue, Shuai, Wen, Feng, Lu, Bu, Faqian, Zhu, Yumeng, Zhang, Lan, Wang, Guan, Ouyang, Liang
Publicado 2022