For Better or Worse: The Potential for Dose Limiting the On-Target Toxicity of PI 3-Kinase Inhibitors

por Buchanan, Christina M., Lee, Kate L., Shepherd, Peter R.
Publicado 2019

Can reducing sitting time in the university setting improve the cardiometabolic health of college students?

por Butler, Karrie M, Ramos, Joyce S, Buchanan, Christina A, Dalleck, Lance C
Publicado 2018

Enzyme activity effects of N-terminal His-tag attached to catalytic sub-unit of phosphoinositide-3-kinase

por Dickson, James M. J., Lee, Woo-Jeong, Shepherd, Peter R., Buchanan, Christina M.
Publicado 2013

The Effect of Detraining after a Period of Training on Cardiometabolic Health in Previously Sedentary Individuals

por Nolan, Paul B., Keeling, Shawn M., Robitaille, Chantelle A., Buchanan, Christina A., Dalleck, Lance C.
Publicado 2018

Response to BRAF-targeted Therapy Is Enhanced by Cotargeting VEGFRs or WNT/β-Catenin Signaling in BRAF-mutant Colorectal Cancer Models

por Tran, Khanh B., Kolekar, Sharada, Wang, Qian, Shih, Jen-Hsing, Buchanan, Christina M., Deva, Sanjeev, Shepherd, Peter R.
Publicado 2022

Preptin Deficiency Does Not Protect against High‐Fat Diet‐Induced Metabolic Dysfunction or Bone Loss in Mice

por Buckels, Emma J., Tan, Joey, Hsu, Huai‐Ling, Zhu, Yuting, Buchanan, Christina M., Matthews, Brya G., Lee, Kate L.
Publicado 2023

Oncogenic Mutations of p110α Isoform of PI 3-Kinase Upregulate Its Protein Kinase Activity

por Buchanan, Christina M., Dickson, James M. J., Lee, Woo-Jeong, Guthridge, Mark A., Kendall, Jackie D., Shepherd, Peter R.
Publicado 2013

Uncovering social structures and informational prejudices to reduce inequity in delivery and uptake of new molecular technologies

por Filoche, Sara, Stone, Peter, Cram, Fiona, Bacharach, Sondra, Dowell, Anthony, Sika-Paotonu, Dianne, Beard, Angela, Ormandy, Judy, Buchanan, Christina, Thunders, Michelle, Dew, Kevin
Publicado 2020

A drug targeting only p110α can block phosphoinositide 3-kinase signalling and tumour growth in certain cell types

por Jamieson, Stephen, Flanagan, Jack U., Kolekar, Sharada, Buchanan, Christina, Kendall, Jackie D., Lee, Woo-Jeong, Rewcastle, Gordon W., Denny, William A., Singh, Ripudaman, Dickson, James, Baguley, Bruce C., Shepherd, Peter R.
Publicado 2011

Biological characterization of SN32976, a selective inhibitor of PI3K and mTOR with preferential activity to PI3Kα, in comparison to established pan PI3K inhibitors

por Rewcastle, Gordon W, Kolekar, Sharada, Buchanan, Christina M, Gamage, Swarna A, Giddens, Anna C, Tsang, Kit Y, Kendall, Jackie D, Singh, Ripudaman, Lee, Woo-Jeong, Smith, Greg C, Han, Weiping, Matthews, David J, Denny, William A, Shepherd, Peter R, Jamieson, Stephen M.F
Publicado 2017

Desacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance

por Mountjoy, Kathleen G., Caron, Alexandre, Hubbard, Kristina, Shome, Avik, Grey, Angus C., Sun, Bo, Bould, Sarah, Middleditch, Martin, Pontré, Beau, McGregor, Ailsa, Harris, Paul W.R., Kowalczyk, Renata, Brimble, Margaret A., Botha, Rikus, Tan, Karen M.L., Piper, Sarah J., Buchanan, Christina, Lee, Syann, Coll, Anthony P., Elmquist, Joel K.
Publicado 2017