Contrasting genetic architectures in different mouse reference populations used for studying complex traits

por Buchner, David A., Nadeau, Joseph H.
Publicado 2015

Widespread epistasis regulates glucose homeostasis and gene expression

por Chen, Anlu, Liu, Yang, Williams, Scott M., Morris, Nathan, Buchner, David A.
Publicado 2017

A Novel Mapping Strategy Utilizing Mouse Chromosome Substitution Strains Identifies Multiple Epistatic Interactions That Regulate Complex Traits

por Miller, Anna K., Chen, Anlu, Bartlett, Jacquelaine, Wang, Li, Williams, Scott M., Buchner, David A.
Publicado 2020

Maternal Nutrition Induces Pervasive Gene Expression Changes but No Detectable DNA Methylation Differences in the Liver of Adult Offspring

por Cannon, Matthew V., Buchner, David A., Hester, James, Miller, Hadley, Sehayek, Ephraim, Nadeau, Joseph H., Serre, David
Publicado 2014

Low-Dose Anti-HIV Drug Efavirenz Mitigates Retinal Vascular Lesions in a Mouse Model of Alzheimer’s Disease

por El-Darzi, Nicole, Mast, Natalia, Buchner, David A., Saadane, Aicha, Dailey, Brian, Trichonas, Georgios, Pikuleva, Irina A.
Publicado 2022

Colon Cancer-Upregulated Long Non-Coding RNA lincDUSP Regulates Cell Cycle Genes and Potentiates Resistance to Apoptosis

por Forrest, Megan E., Saiakhova, Alina, Beard, Lydia, Buchner, David A., Scacheri, Peter C., LaFramboise, Thomas, Markowitz, Sanford, Khalil, Ahmad M.
Publicado 2018

eIF2A‐knockout mice reveal decreased life span and metabolic syndrome

por Anderson, Richard, Agarwal, Anchal, Ghosh, Arnab, Guan, Bo‐Jhih, Casteel, Jackson, Dvorina, Nina, Baldwin, William M., Mazumder, Barsanjit, Nazarko, Taras Y., Merrick, William C., Buchner, David A., Hatzoglou, Maria, Kondratov, Roman V., Komar, Anton A.
Publicado 2021

PACT-mediated PKR activation acts as a hyperosmotic stress intensity sensor weakening osmoadaptation and enhancing inflammation

por Farabaugh, Kenneth T, Krokowski, Dawid, Guan, Bo-Jhih, Gao, Zhaofeng, Gao, Xing-Huang, Wu, Jing, Jobava, Raul, Ray, Greeshma, de Jesus, Tristan J, Bianchi, Massimiliano G, Chukwurah, Evelyn, Bussolati, Ovidio, Kilberg, Michael, Buchner, David A, Sen, Ganes C, Cotton, Calvin, McDonald, Christine, Longworth, Michelle, Ramakrishnan, Parameswaran, Hatzoglou, Maria
Publicado 2020

Mutations in PIK3C2A cause syndromic short stature, skeletal abnormalities, and cataracts associated with ciliary dysfunction

por Tiosano, Dov, Baris, Hagit N., Chen, Anlu, Hitzert, Marrit M., Schueler, Markus, Gulluni, Federico, Wiesener, Antje, Bergua, Antonio, Mory, Adi, Copeland, Brett, Gleeson, Joseph G., Rump, Patrick, van Meer, Hester, Sival, Deborah A., Haucke, Volker, Kriwinsky, Josh, Knaup, Karl X., Reis, André, Hauer, Nadine N., Hirsch, Emilio, Roepman, Ronald, Pfundt, Rolph, Thiel, Christian T., Wiesener, Michael S., Aslanyan, Mariam G., Buchner, David A.
Publicado 2019