The Tryp and the Pendulum

por Buckner, Frederick S.
Publicado 2021

Hydroxychloroquine for Treatment of SARS‐CoV‐2 Infection? Improving Our Confidence in a Model‐Based Approach to Dose Selection

por Arnold, Samuel L.M., Buckner, Frederick
Publicado 2020

An Essential Farnesylated Kinesin in Trypanosoma brucei

por Engelson, Erin J., Buckner, Frederick S., Van Voorhis, Wesley C.
Publicado 2011

Identification of Three Classes of Heteroaromatic Compounds with Activity against Intracellular Trypanosoma cruzi by Chemical Library Screening

por Bettiol, Esther, Samanovic, Marie, Murkin, Andrew S., Raper, Jayne, Buckner, Frederick, Rodriguez, Ana
Publicado 2009

Synergy Testing of FDA-Approved Drugs Identifies Potent Drug Combinations against Trypanosoma cruzi

por Planer, Joseph D., Hulverson, Matthew A., Arif, Jennifer A., Ranade, Ranae M., Don, Robert, Buckner, Frederick S.
Publicado 2014

1-Benzyl-3-aryl-2-thiohydantoin Derivatives as New Anti-Trypanosoma brucei Agents: SAR and in Vivo Efficacy

por Buchynskyy, Andriy, Gillespie, J. Robert, Herbst, Zackary M., Ranade, Ranae M., Buckner, Frederick S., Gelb, Michael H.
Publicado 2017

Phenotypic Drug Discovery for Human African Trypanosomiasis: A Powerful Approach

por Buckner, Frederick S., Buchynskyy, Andriy, Nagendar, Pendem, Patrick, Donald A., Gillespie, J. Robert, Herbst, Zackary, Tidwell, Richard R., Gelb, Michael H.
Publicado 2020

Bioactivity of Farnesyltransferase Inhibitors Against Entamoeba histolytica and Schistosoma mansoni

por Probst, Alexandra, Nguyen, Thi N., El-Sakkary, Nelly, Skinner, Danielle, Suzuki, Brian M., Buckner, Frederick S., Gelb, Michael H., Caffrey, Conor R., Debnath, Anjan
Publicado 2019

Synthesis and Structure−Activity Relationships of Imidazopyridine/Pyrimidine‐ and Furopyridine‐Based Anti‐infective Agents against Trypanosomiases

por Silva, Daniel G., Junker, Anna, de Melo, Shaiani M. G., Fumagalli, Fernando, Gillespie, J. Robert, Molasky, Nora, Buckner, Frederick S., Matheeussen, An, Caljon, Guy, Maes, Louis, Emery, Flavio S.
Publicado 2020

Recent Developments in Drug Discovery for Leishmaniasis and Human African Trypanosomiasis

por Nagle, Advait S., Khare, Shilpi, Kumar, Arun Babu, Supek, Frantisek, Buchynskyy, Andriy, Mathison, Casey J. N., Chennamaneni, Naveen Kumar, Pendem, Nagendar, Buckner, Frederick S., Gelb, Michael H., Molteni, Valentina
Publicado 2014

5-Fluoroimidazo[4,5-b]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors

por Zhang, Zhongsheng, Koh, Cho Yeow, Ranade, Ranae M., Shibata, Sayaka, Gillespie, J. Robert, Hulverson, Matthew A., Huang, Wenlin, Nguyen, Jasmine, Pendem, Nagendar, Gelb, Michael H., Verlinde, Christophe L. M. J., Hol, Wim G. J., Buckner, Frederick S., Fan, Erkang
Publicado 2016

Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness

por Koh, Cho Yeow, Kim, Jessica E., Wetzel, Allan B., de van der Schueren, Will J., Shibata, Sayaka, Ranade, Ranae M., Liu, Jiyun, Zhang, Zhongsheng, Gillespie, J. Robert, Buckner, Frederick S., Verlinde, Christophe L. M. J., Fan, Erkang, Hol, Wim G. J.
Publicado 2014

Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis

por Ojo, Kayode K., Ranade, Ranae M., Zhang, Zhongsheng, Dranow, David M., Myers, Janette B., Choi, Ryan, Nakazawa Hewitt, Steve, Edwards, Thomas E., Davies, Douglas R., Lorimer, Donald, Boyle, Stephen M., Barrett, Lynn K., Buckner, Frederick S., Fan, Erkang, Van Voorhis, Wesley C.
Publicado 2016

Correction: Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis

por Ojo, Kayode K., Ranade, Ranae M., Zhang, Zhongsheng, Dranow, David M., Myers, Janette B., Choi, Ryan, Nakazawa Hewitt, Steve, Edwards, Thomas E., Davies, Douglas R., Lorimer, Donald, Boyle, Stephen M., Barrett, Lynn K., Buckner, Frederick S., Fan, Erkang, Van Voorhis, Wesley C.
Publicado 2016

Clinical Features and Outcomes of 105 Hospitalized Patients With COVID-19 in Seattle, Washington

por Buckner, Frederick S, McCulloch, Denise J, Atluri, Vidya, Blain, Michela, McGuffin, Sarah A, Nalla, Arun K, Huang, Meei-Li, Greninger, Alex L, Jerome, Keith R, Cohen, Seth A, Neme, Santiago, Green, Margaret L, Chu, Helen Y, Kim, H Nina
Publicado 2020

Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness

por Khare, Shilpi, Nagle, Advait S., Biggart, Agnes, Lai, Yin H., Liang, Fang, Davis, Lauren C., Barnes, S. Whitney, Mathison, Casey J. N., Myburgh, Elmarie, Gao, Mu-Yun, Gillespie, J. Robert, Liu, Xianzhong, Tan, Jocelyn L., Stinson, Monique, Rivera, Ianne C., Ballard, Jaime, Yeh, Vince, Groessl, Todd, Federe, Glenn, Koh, Hazel X. Y., Venable, John D., Bursulaya, Badry, Shapiro, Michael, Mishra, Pranab K., Spraggon, Glen, Brock, Ansgar, Mottram, Jeremy C., Buckner, Frederick S., Rao, Srinivasa P. S., Wen, Ben G., Walker, John R., Tuntland, Tove, Molteni, Valentina, Glynne, Richard J., Supek, Frantisek
Publicado 2016

Setting Our Sights on Infectious Diseases

por De Rycker, Manu, Horn, David, Aldridge, Bree, Amewu, Richard K., Barry, Clifton E., Buckner, Frederick S., Cook, Sarah, Ferguson, Michael A. J., Gobeau, Nathalie, Herrmann, Jennifer, Herrling, Paul, Hope, William, Keiser, Jennifer, Lafuente-Monasterio, Maria Jose, Leeson, Paul D., Leroy, Didier, Manjunatha, Ujjini H., McCarthy, James, Miles, Timothy J., Mizrahi, Valerie, Moshynets, Olena, Niles, Jacquin, Overington, John P., Pottage, John, Rao, Srinivasa P. S., Read, Kevin D., Ribeiro, Isabela, Silver, Lynn L., Southern, Jen, Spangenberg, Thomas, Sundar, Shyam, Taylor, Caitlin, Van Voorhis, Wes, White, Nicholas J., Wyllie, Susan, Wyatt, Paul G., Gilbert, Ian H.
Publicado 2019