Mathematical modeling suggests cytotoxic T lymphocytes control growth of B16 tumor cells in collagin-fibrin gels by cytolytic and non-lytic mechanisms

por Majumder, Barun, Budhu, Sadna, Ganusov, Vitaly V.
Publicado 2023

Cytotoxic T Lymphocytes Control Growth of B16 Tumor Cells in Collagen–Fibrin Gels by Cytolytic and Non-Lytic Mechanisms

por Majumder, Barun, Budhu, Sadna, Ganusov, Vitaly V.
Publicado 2023

Blockade of Treg derived TGF-β abrogates suppression of effector T cell function within the tumor microenvironment

por Budhu, Sadna, Schaer, David, Li, Yongbiao, Houghton, Alan, Silverstein, Samuel, Merghoub, Taha, Wolchok, Jedd
Publicado 2013

Blockade of surface bound TGF-β abrogates Treg suppression of effector T cell function within the tumor microenvironment

por Budhu, Sadna, Schaer, David, Li, Yongbiao, Houghton, Alan, Silverstein, Samuel, Merghoub, Taha, Wolchok, Jedd D
Publicado 2014

Impairment of Treg suppression by GITR ligation is effective selectively in the context of a pro-inflammatory tumor microenvironment

por Zappasodi, Roberta, Budhu, Sadna, Schaer, David, Yang, Xia, Zhong, Hong, Merghoub, Taha, Wolchok, Jedd D
Publicado 2014

Surface Acoustic Waves Enhance Neutrophil Killing of Bacteria

por Loike, John D., Plitt, Anna, Kothari, Komal, Zumeris, Jona, Budhu, Sadna, Kavalus, Kaitlyn, Ray, Yonatan, Jacob, Harold
Publicado 2013

Cytokine release syndrome after radiation therapy: case report and review of the literature

por Barker, Christopher A., Kim, Samuel K., Budhu, Sadna, Matsoukas, Konstantina, Daniyan, Anthony F., D’Angelo, Sandra P.
Publicado 2018

CD8(+) T cell concentration determines their efficiency in killing cognate antigen–expressing syngeneic mammalian cells in vitro and in mouse tissues

por Budhu, Sadna, Loike, John D., Pandolfi, Ashley, Han, Soo, Catalano, Geoffrey, Constantinescu, Andrei, Clynes, Raphael, Silverstein, Samuel C.
Publicado 2010

Differential Regulation of β(1) Integrins by Chemoattractants Regulates Neutrophil Migration through Fibrin

por Loike, John D., Cao, Long, Budhu, Sadna, Marcantonio, Eugene E., Khoury, Joseph El, Hoffman, Stanley, Yednock, Ted A., Silverstein, Samuel C.
Publicado 1999

Neoadjuvant vascular-targeted photodynamic therapy improves survival and reduces recurrence and progression in a mouse model of urothelial cancer

por Rosenzweig, Barak, Corradi, Renato B., Budhu, Sadna, Alvim, Ricardo, Recabal, Pedro, La Rosa, Stephen, Somma, Alex, Monette, Sebastien, Scherz, Avigdor, Kim, Kwanghee, Coleman, Jonathan A.
Publicado 2021

Isoform specific anti-TGFβ therapy enhances antitumor efficacy in mouse models of cancer

por Gupta, Aditi, Budhu, Sadna, Fitzgerald, Kelly, Giese, Rachel, Michel, Adam O., Holland, Aliya, Campesato, Luis Felipe, van Snick, Jacques, Uyttenhove, Catherine, Ritter, Gerd, Wolchok, Jedd D., Merghoub, Taha
Publicado 2021

Phase Ib Trial of Phenformin in Patients with V600-mutated Melanoma Receiving Dabrafenib and Trametinib

por Chapman, Paul B., Klang, Mark, Postow, Michael A., Shoushtari, Alexander Noor, Sullivan, Ryan J., Wolchok, Jedd D., Merghoub, Taha, Budhu, Sadna, Wong, Phillip, Callahan, Margaret K., Zheng, Bin, Zippin, Jonathan
Publicado 2023

Induction of tumoricidal function in CD4(+) T cells is associated with concomitant memory and terminally differentiated phenotype

por Hirschhorn-Cymerman, Daniel, Budhu, Sadna, Kitano, Shigehisa, Liu, Cailian, Zhao, Feng, Zhong, Hong, Lesokhin, Alexander M., Avogadri-Connors, Francesca, Yuan, Jianda, Li, Yanyun, Houghton, Alan N., Merghoub, Taha, Wolchok, Jedd D.
Publicado 2012

MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration

por Cebrián, Carolina, Zucca, Fabio A., Mauri, Pierluigi, Steinbeck, Julius A., Studer, Lorenz, Scherzer, Clemens R., Kanter, Ellen, Budhu, Sadna, Mandelbaum, Jonathan, Vonsattel, Jean P., Zecca, Luigi, Loike, John D., Sulzer, David
Publicado 2014

Cyclophosphamide enhances the antitumor potency of GITR engagement by increasing oligoclonal cytotoxic T cell fitness

por Hirschhorn, Daniel, Betof Warner, Allison, Maniyar, Rachana, Chow, Andrew, Mangarin, Levi M.B., Cohen, Adam D., Hamadene, Linda, Rizzuto, Gabrielle A., Budhu, Sadna, Suek, Nathan, Liu, Cailian, Houghton, Alan N., Merghoub, Taha, Wolchok, Jedd D.
Publicado 2021

Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma

por Budhu, Sadna, Giese, Rachel, Gupta, Aditi, Fitzgerald, Kelly, Zappasodi, Roberta, Schad, Sara, Hirschhorn, Daniel, Campesato, Luis Felipe, De Henau, Olivier, Gigoux, Mathieu, Liu, Cailian, Mazo, Gregory, Deng, Liang, Barker, Christopher A., Wolchok, Jedd D., Merghoub, Taha
Publicado 2021

APR-246 increases tumor antigenicity independent of p53

por Michels, Judith, Venkatesh, Divya, Liu, Cailian, Budhu, Sadna, Zhong, Hong, George, Mariam M, Thach, Daniel, Yao, Zhong-Ke, Ouerfelli, Ouathek, Liu, Hengrui, Stockwell, Brent R, Campesato, Luis Felipe, Zamarin, Dmitriy, Zappasodi, Roberta, Wolchok, Jedd D, Merghoub, Taha
Publicado 2023

Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine

por Campesato, Luis Felipe, Budhu, Sadna, Tchaicha, Jeremy, Weng, Chien-Huan, Gigoux, Mathieu, Cohen, Ivan Jose, Redmond, David, Mangarin, Levi, Pourpe, Stephane, Liu, Cailian, Zappasodi, Roberta, Zamarin, Dmitriy, Cavanaugh, Jill, Castro, Alfredo C., Manfredi, Mark G., McGovern, Karen, Merghoub, Taha, Wolchok, Jedd D.
Publicado 2020

Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions

por Schad, Sara E., Chow, Andrew, Mangarin, Levi, Pan, Heng, Zhang, Jiajia, Ceglia, Nicholas, Caushi, Justina X., Malandro, Nicole, Zappasodi, Roberta, Gigoux, Mathieu, Hirschhorn, Daniel, Budhu, Sadna, Amisaki, Masataka, Arniella, Monica, Redmond, David, Chaft, Jamie, Forde, Patrick M., Gainor, Justin F., Hellmann, Matthew D., Balachandran, Vinod, Shah, Sohrab, Smith, Kellie N., Pardoll, Drew, Elemento, Olivier, Wolchok, Jedd D., Merghoub, Taha
Publicado 2022

Increased p53 expression induced by APR-246 reprograms tumor-associated macrophages to augment immune checkpoint blockade

por Ghosh, Arnab, Michels, Judith, Mezzadra, Riccardo, Venkatesh, Divya, Dong, Lauren, Gomez, Ricardo, Samaan, Fadi, Ho, Yu-Jui, Campesato, Luis Felipe, Mangarin, Levi, Fak, John, Suek, Nathan, Holland, Aliya, Liu, Cailian, Abu-Akeel, Mohsen, Bykov, Yonina, Zhong, Hong, Fitzgerald, Kelly, Budhu, Sadna, Chow, Andrew, Zappasodi, Roberta, Panageas, Katherine S., de Henau, Olivier, Ruscetti, Marcus, Lowe, Scott W., Merghoub, Taha, Wolchok, Jedd D.
Publicado 2022