Gilteritinib-induced upregulation of S100A9 is mediated through BCL6 in acute myeloid leukemia

por Zavorka Thomas, Megan E., Jeon, Jae Yoon, Talebi, Zahra, Buelow, Daelynn R., Silvaroli, Josie, Campbell, Moray J., Sparreboom, Alex, Pabla, Navjot, Baker, Sharyn D.
Publicado 2021

DNA Methylation‐Based Epigenetic Repression of SLC22A4 Promotes Resistance to Cytarabine in Acute Myeloid Leukemia

por Buelow, Daelynn R., Anderson, Jason T., Pounds, Stanley B., Shi, Lei, Lamba, Jatinder K., Hu, Shuiying, Gibson, Alice A., Goodwin, Emily A., Sparreboom, Alex, Baker, Sharyn D.
Publicado 2020

BMX kinase mediates gilteritinib resistance in FLT3-mutated AML through microenvironmental factors

por Buelow, Daelynn R., Bhatnagar, Bhavana, Orwick, Shelley J., Jeon, Jae Yoon, Eisenmann, Eric D., Stromatt, Jack C., Pabla, Navjot Singh, Blachly, James S., Baker, Sharyn D., Blaser, Bradley W.
Publicado 2022

TP-0903 Is Active in Preclinical Models of Acute Myeloid Leukemia with TP53 Mutation/Deletion

por Eisenmann, Eric D., Stromatt, Jack C., Fobare, Sydney, Huang, Kevin M., Buelow, Daelynn R., Orwick, Shelley, Jeon, Jae Yoon, Weber, Robert H., Larsen, Bill, Mims, Alice S., Hertlein, Erin, Byrd, John C., Baker, Sharyn D.
Publicado 2022

Framework of clonal mutations concurrent with WT1 mutations in adults with acute myeloid leukemia: Alliance for Clinical Trials in Oncology study

por Bhatnagar, Bhavana, Kohlschmidt, Jessica, Orwick, Shelley J., Buelow, Daelynn R., Fobare, Sydney, Oakes, Christopher C., Kolitz, Jonathan E., Uy, Geoff, Stock, Wendy, Powell, Bayard L., Nicolet, Deedra, Hertlein, Erin K., Mrózek, Krzysztof, Blachly, James S., Eisfeld, Ann-Kathrin, Baker, Sharyn D., Byrd, John C.
Publicado 2023

A high-throughput screen indicates gemcitabine and JAK inhibitors may be useful for treating pediatric AML

por Drenberg, Christina D., Shelat, Anang, Dang, Jinjun, Cotton, Anitria, Orwick, Shelley J., Li, Mengyu, Jeon, Jae Yoon, Fu, Qiang, Buelow, Daelynn R., Pioso, Marissa, Hu, Shuiying, Inaba, Hiroto, Ribeiro, Raul C., Rubnitz, Jeffrey E., Gruber, Tanja A., Guy, R. Kiplin, Baker, Sharyn D.
Publicado 2019

Uncovering the Genomic Landscape in Newly Diagnosed and Relapsed Pediatric Cytogenetically Normal FLT 3‐ITD AML

por Buelow, Daelynn R., Pounds, Stanley B., Wang, Yong‐Dong, Shi, Lei, Li, Yongjin, Finkelstein, David, Shurtleff, Sheila, Neale, Geoffrey, Inaba, Hiroto, Ribeiro, Raul C., Palumbo, Reid, Garrison, Dominique, Orwick, Shelley J., Blachly, James S., Kroll, Karl, Byrd, John C., Gruber, Tanja A., Rubnitz, Jeffrey E., Baker, Sharyn D.
Publicado 2019

Gilteritinib Inhibits Glutamine Uptake and Utilization in FLT3-ITD–Positive AML

por Zavorka Thomas, Megan E., Lu, Xiyuan, Talebi, Zahra, Jeon, Jae Yoon, Buelow, Daelynn R., Gibson, Alice A., Uddin, Muhammad Erfan, Brinton, Lindsey T., Nguyen, Julie, Collins, Meghan, Lodi, Alessia, Sweeney, Shannon R., Campbell, Moray J., Sweet, Douglas H., Sparreboom, Alex, Lapalombella, Rosa, Tiziani, Stefano, Baker, Sharyn D.
Publicado 2021

TP-0903 is active in models of drug-resistant acute myeloid leukemia

por Jeon, Jae Yoon, Buelow, Daelynn R., Garrison, Dominique A., Niu, Mingshan, Eisenmann, Eric D., Huang, Kevin M., Zavorka Thomas, Megan E., Weber, Robert H., Whatcott, Clifford J., Warner, Steve L., Orwick, Shelley J., Carmichael, Bridget, Stahl, Emily, Brinton, Lindsey T., Lapalombella, Rosa, Blachly, James S., Hertlein, Erin, Byrd, John C., Bhatnagar, Bhavana, Baker, Sharyn D.
Publicado 2020

Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms

por Zhang, Haijiao, Savage, Samantha, Schultz, Anna Reister, Bottomly, Daniel, White, Libbey, Segerdell, Erik, Wilmot, Beth, McWeeney, Shannon K., Eide, Christopher A., Nechiporuk, Tamilla, Carlos, Amy, Henson, Rachel, Lin, Chenwei, Searles, Robert, Ho, Hoang, Lam, Yee Ling, Sweat, Richard, Follit, Courtney, Jain, Vinay, Lind, Evan, Borthakur, Gautam, Garcia-Manero, Guillermo, Ravandi, Farhad, Kantarjian, Hagop M., Cortes, Jorge, Collins, Robert, Buelow, Daelynn R., Baker, Sharyn D., Druker, Brian J., Tyner, Jeffrey W.
Publicado 2019