Mesenchymal stem/stromal cell-based therapy for the treatment of rheumatoid arthritis: An update on preclinical studies

por Lopez-Santalla, Mercedes, Bueren, Juan A., Garin, Marina I.
Publicado 2021

Generation of Functional Neutrophils from a Mouse Model of X-Linked Chronic Granulomatous Disorder Using Induced Pluripotent Stem Cells

por Mukherjee, Sayandip, Santilli, Giorgia, Blundell, Michael P., Navarro, Susana, Bueren, Juan A., Thrasher, Adrian J.
Publicado 2011

Mosaicism in Fanconi anemia: concise review and evaluation of published cases with focus on clinical course of blood count normalization

por Nicoletti, Eileen, Rao, Gayatri, Bueren, Juan A., Río, Paula, Navarro, Susana, Surrallés, Jordi, Choi, Grace, Schwartz, Jonathan D.
Publicado 2020

Improved efficacy of mesenchymal stromal cells stably expressing CXCR4 and IL-10 in a xenogeneic graft versus host disease mouse model

por Hervás-Salcedo, Rosario, Fernández-García, María, Hernando-Rodríguez, Miriam, Suárez-Cabrera, Cristian, Bueren, Juan A., Yáñez, Rosa M.
Publicado 2023

Adenine base editing efficiently restores the function of Fanconi anemia hematopoietic stem and progenitor cells

por Siegner, Sebastian M., Ugalde, Laura, Clemens, Alexandra, Garcia-Garcia, Laura, Bueren, Juan A., Rio, Paula, Karasu, Mehmet E., Corn, Jacob E.
Publicado 2022

Gene editing of PKLR gene in human hematopoietic progenitors through 5’ and 3’ UTR modified TALEN mRNA

por Quintana-Bustamante, Oscar, Fañanas-Baquero, Sara, Orman, Israel, Torres, Raul, Duchateau, Philippe, Poirot, Laurent, Gouble, Agnès, Bueren, Juan A., Segovia, Jose C.
Publicado 2019

Enhanced Susceptibility of Galectin-1 Deficient Mice to Experimental Colitis

por Fernandez-Perez, Raquel, Lopez-Santalla, Mercedes, Sánchez-Domínguez, Rebeca, Alberquilla, Omaira, Gutiérrez-Cañas, Irene, Juarranz, Yasmina, Bueren, Juan A., Garin, Marina I.
Publicado 2021

Adipose‐derived mesenchymal stromal cells modulate experimental autoimmune arthritis by inducing an early regulatory innate cell signature

por Lopez‐Santalla, Mercedes, Menta, Ramon, Mancheño‐Corvo, Pablo, Lopez‐Belmonte, Juan, DelaRosa, Olga, Bueren, Juan A., Dalemans, Wilfried, Lombardo, Eleuterio, Garin, Marina I.
Publicado 2016

Comparative Analysis between the In Vivo Biodistribution and Therapeutic Efficacy of Adipose-Derived Mesenchymal Stromal Cells Administered Intraperitoneally in Experimental Coliti...

por Lopez-Santalla, Mercedes, Mancheño-Corvo, Pablo, Escolano, Amelia, Menta, Ramon, Delarosa, Olga, Redondo, Juan M., Bueren, Juan A., Dalemans, Wilfried, Lombardo, Eleuterio, Garin, Marina I.
Publicado 2018

Lentiviral Vector-Mediated Correction of a Mouse Model of Leukocyte Adhesion Deficiency Type I

por Leon-Rico, Diego, Aldea, Montserrat, Sanchez-Baltasar, Raquel, Mesa-Nuñez, Cristina, Record, Julien, Burns, Siobhan O., Santilli, Giorgia, Thrasher, Adrian J., Bueren, Juan A., Almarza, Elena
Publicado 2016

Generation of dyskeratosis congenita-like hematopoietic stem cells through the stable inhibition of DKC1

por Carrascoso-Rubio, Carlos, Zittersteijn, Hidde A., Pintado-Berninches, Laura, Fernández-Varas, Beatriz, Lozano, M. Luz, Manguan-Garcia, Cristina, Sastre, Leandro, Bueren, Juan A., Perona, Rosario, Guenechea, Guillermo
Publicado 2021

Specific correction of pyruvate kinase deficiency-causing point mutations by CRISPR/Cas9 and single-stranded oligodeoxynucleotides

por Fañanas-Baquero, Sara, Morín, Matías, Fernández, Sergio, Ojeda-Perez, Isabel, Dessy-Rodriguez, Mercedes, Giurgiu, Miruna, Bueren, Juan A., Moreno-Pelayo, Miguel Angel, Segovia, Jose Carlos, Quintana-Bustamante, Oscar
Publicado 2023

Preclinical safety and efficacy of lentiviral-mediated gene therapy for leukocyte adhesion deficiency type I

por Mesa-Núñez, Cristina, Damián, Carlos, Fernández-García, María, Díez, Begoña, Rao, Gayatri, Schwartz, Jonathan D., Law, Ken M., Sevilla, Julián, Río, Paula, Yáñez, Rosa, Bueren, Juan A., Almarza, Elena
Publicado 2022

Mesenchymal stromal cells enhance the engraftment of hematopoietic stem cells in an autologous mouse transplantation model

por Fernández-García, María, Yañez, Rosa M., Sánchez-Domínguez, Rebeca, Hernando-Rodriguez, Miriam, Peces-Barba, Miguel, Herrera, Guadalupe, O’Connor, Jose E., Segovia, José C., Bueren, Juan A., Lamana, María L.
Publicado 2015

Transforming and Tumorigenic Activity of JAK2 by Fusion to BCR: Molecular Mechanisms of Action of a Novel BCR-JAK2 Tyrosine-Kinase

por Cuesta-Domínguez, Álvaro, Ortega, Mara, Ormazábal, Cristina, Santos-Roncero, Matilde, Galán-Díez, Marta, Steegmann, Juan Luis, Figuera, Ángela, Arranz, Eva, Vizmanos, José Luis, Bueren, Juan A., Río, Paula, Fernández-Ruiz, Elena
Publicado 2012

Epigenetic Alterations in Fanconi Anaemia: Role in Pathophysiology and Therapeutic Potential

por Belo, Hélio, Silva, Gabriela, Cardoso, Bruno A., Porto, Beatriz, Minguillon, Jordi, Barbot, José, Coutinho, Jorge, Casado, Jose A., Benedito, Manuela, Saturnino, Hema, Costa, Emília, Bueren, Juan A., Surralles, Jordi, Almeida, Antonio
Publicado 2015

Biodistribution and Efficacy of Human Adipose-Derived Mesenchymal Stem Cells Following Intranodal Administration in Experimental Colitis

por Lopez-Santalla, Mercedes, Mancheño-Corvo, Pablo, Escolano, Amelia, Menta, Ramon, DelaRosa, Olga, Abad, Jose Luis, Büscher, Dirk, Redondo, Juan M., Bueren, Juan A., Dalemans, Wilfried, Lombardo, Eleuterio, Garin, Marina I.
Publicado 2017

Intralymphatic Administration of Adipose Mesenchymal Stem Cells Reduces the Severity of Collagen-Induced Experimental Arthritis

por Mancheño-Corvo, Pablo, Lopez-Santalla, Mercedes, Menta, Ramon, DelaRosa, Olga, Mulero, Francisca, del Rio, Borja, Ramirez, Cristina, Büscher, Dirk, Bueren, Juan A., Lopez-Belmonte, Juan, Dalemans, Wilfried, Garin, Marina I., Lombardo, Eleuterio
Publicado 2017

Bcr/Abl Interferes with the Fanconi Anemia/BRCA Pathway: Implications in the Chromosomal Instability of Chronic Myeloid Leukemia Cells

por Valeri, Antonio, Alonso-Ferrero, Maria Eugenia, Río, Paula, Pujol, María Roser, Casado, José A., Pérez, Laura, Jacome, Ariana, Agirre, Xabier, Calasanz, Maria José, Hanenberg, Helmut, Surrallés, Jordi, Prosper, Felipe, Albella, Beatriz, Bueren, Juan A.
Publicado 2010

In Vitro and In Vivo Genetic Disease Modeling via NHEJ-Precise Deletions Using CRISPR-Cas9

por López-Manzaneda, Sergio, Ojeda-Pérez, Isabel, Zabaleta, Nerea, García-Torralba, Aída, Alberquilla, Omaira, Torres, Raúl, Sánchez-Domínguez, Rebeca, Torella, Laura, Olivier, Emmanuel, Mountford, Joanne, Ramírez, Juan C., Bueren, Juan A., González-Aseguinolaza, Gloria, Segovia, Jose-Carlos
Publicado 2020