LCK over-expression drives STAT5 oncogenic signaling in PAX5 translocated BCP-ALL patients

por Cazzaniga, Valeria, Bugarin, Cristina, Bardini, Michela, Giordan, Marco, te Kronnie, Geertruy, Basso, Giuseppe, Biondi, Andrea, Fazio, Grazia, Cazzaniga, Giovanni
Publicado 2015

Either IL-7 activation of JAK-STAT or BEZ inhibition of PI3K-AKT-mTOR pathways dominates the single-cell phosphosignature of ex vivo treated pediatric T-cell acute lymphoblastic le...

por Kuzilková, Daniela, Bugarin, Cristina, Rejlova, Katerina, Schulz, Axel R., Mei, Henrik E., Paganin, Maddalena, Biffi, Alessandra, Biondi, Andrea, Kalina, Tomas, Gaipa, Giuseppe
Publicado 2021

Simultaneous Overexpression of Functional Human HO-1, E5NT and ENTPD1 Protects Murine Fibroblasts against TNF-α-Induced Injury In Vitro

por Cinti, Alessandro, De Giorgi, Marco, Chisci, Elisa, Arena, Claudia, Galimberti, Gloria, Farina, Laura, Bugarin, Cristina, Rivolta, Ilaria, Gaipa, Giuseppe, Smolenski, Ryszard Tom, Cerrito, Maria Grazia, Lavitrano, Marialuisa, Giovannoni, Roberto
Publicado 2015

Mutational analysis of ribosomal proteins in a cohort of pediatric patients with T-cell acute lymphoblastic leukemia reveals Q123R, a novel mutation in RPL10

por Bacci, Lorenza, Indio, Valentina, Rambaldelli, Guglielmo, Bugarin, Cristina, Magliocchetti, Franco, Del Rio, Alberto, Pollutri, Daniela, Melchionda, Fraia, Pession, Andrea, Lanciotti, Marina, Dufour, Carlo, Gaipa, Giuseppe, Montanaro, Lorenzo, Penzo, Marianna
Publicado 2022

Metronomic combination of Vinorelbine and 5Fluorouracil is able to inhibit triple-negative breast cancer cells. Results from the proof-of-concept VICTOR-0 study

por Cerrito, Maria Grazia, De Giorgi, Marco, Pelizzoni, Davide, Bonomo, Sara Maria, Digiacomo, Nunzio, Scagliotti, Arianna, Bugarin, Cristina, Gaipa, Giuseppe, Grassilli, Emanuela, Lavitrano, Marialuisa, Giovannoni, Roberto, Bidoli, Paolo, Cazzaniga, Marina Elena
Publicado 2018

Abnormal B-Cell Maturation and Increased Transitional B Cells in CBL Syndrome

por Saettini, Francesco, Coliva, Tiziana Angela, Vendemini, Francesca, Galbiati, Marta, Bugarin, Cristina, Masetti, Riccardo, Moratto, Daniele, Chiarini, Marco, Guerra, Fabiola, Iascone, Maria, Badolato, Raffaele, Cazzaniga, Giovanni, Niemeyer, Charlotte, Flotho, Christian, Biondi, Andrea
Publicado 2022

The TGF-β pathway is activated by 5-fluorouracil treatment in drug resistant colorectal carcinoma cells

por Romano, Gabriele, Santi, Ludovica, Bianco, Maria Rosaria, Giuffrè, Maria Rita, Pettinato, Mariateresa, Bugarin, Cristina, Garanzini, Cristina, Savarese, Leonilde, Leoni, Silvia, Cerrito, Maria Grazia, Leone, Biagio Eugenio, Gaipa, Giuseppe, Grassilli, Emanuela, Papa, Michele, Lavitrano, Marialuisa, Giovannoni, Roberto
Publicado 2016

SRC/ABL inhibition disrupts CRLF2-driven signaling to induce cell death in B-cell acute lymphoblastic leukemia

por Sarno, Jolanda, Savino, Angela M., Buracchi, Chiara, Palmi, Chiara, Pinto, Stefania, Bugarin, Cristina, Jager, Astraea, Bresolin, Silvia, Barber, Ruth C., Silvestri, Daniela, Israeli, Shai, Dyer, Martin J.S., Cazzaniga, Giovanni, Nolan, Garry P., Biondi, Andrea, Davis, Kara L., Gaipa, Giuseppe
Publicado 2018

Case Report: Hypomorphic Function and Somatic Reversion in DOCK8 Deficiency in One Patient With Two Novel Variants and Sclerosing Cholangitis

por Saettini, Francesco, Fazio, Grazia, Moratto, Daniele, Galbiati, Marta, Zucchini, Nicola, Ippolito, Davide, Dinelli, Marco Emilio, Imberti, Luisa, Mauri, Mario, Melzi, Maria Luisa, Bonanomi, Sonia, Gerussi, Alessio, Pinelli, Marinella, Barisani, Chiara, Bugarin, Cristina, Chiarini, Marco, Giacomelli, Mauro, Piazza, Rocco, Cazzaniga, Giovanni, Invernizzi, Pietro, Giliani, Silvia Clara, Badolato, Raffaele, Biondi, Andrea
Publicado 2021

CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia

por Palmi, Chiara, Savino, Angela M., Silvestri, Daniela, Bronzini, Ilaria, Cario, Gunnar, Paganin, Maddalena, Buldini, Barbara, Galbiati, Marta, Muckenthaler, Martina U., Bugarin, Cristina, Mina, Pamela Della, Nagel, Stefan, Barisone, Elena, Casale, Fiorina, Locatelli, Franco, Nigro, Luca Lo, Micalizzi, Concetta, Parasole, Rosanna, Pession, Andrea, Putti, Maria C., Santoro, Nicola, Testi, Anna M., Ziino, Ottavio, Kulozik, Andreas E., Zimmermann, Martin, Schrappe, Martin, Villa, Antonello, Gaipa, Giuseppe, Basso, Giuseppe, Biondi, Andrea, Valsecchi, Maria G., Stanulla, Martin, Conter, Valentino, te Kronnie, Geertruy, Cazzaniga, Giovanni
Publicado 2016