Loss of HAI-2 in mice with decreased prostasin activity leads to an early-onset intestinal failure resembling congenital tufting enteropathy

por Szabo, Roman, Bugge, Thomas H.
Publicado 2018

Imaging collagen degradation in vivo highlights a key role for M2-polarized macrophages in extracellular matrix degradation

por Madsen, Daniel H, Bugge, Thomas H
Publicado 2013

The source of matrix-degrading enzymes in human cancer: Problems of research reproducibility and possible solutions

por Madsen, Daniel H., Bugge, Thomas H.
Publicado 2015

Membrane-Anchored Serine Proteases in Health and Disease

por Antalis, Toni M., Bugge, Thomas H., Wu, Qingyu
Publicado 2011

Early-onset tufting enteropathy in HAI-2-deficient mice is independent of matriptase-mediated cleavage of EpCAM

por Szabo, Roman, Kawaguchi, Makiko, Kataoka, Hiroaki, Bugge, Thomas H.
Publicado 2023

Suppression of Tumorigenicity-14, encoding matriptase, is a critical suppressor of colitis and colitis-associated colon carcinogenesis

por Kosa, Peter, Szabo, Roman, Molinolo, Alfredo A., Bugge, Thomas H.
Publicado 2011

Live Imaging and Quantification of Neutrophil Extracellular Trap Formation

por Silva, Lakmali Munasinghage, Moutsopoulos, Niki, Bugge, Thomas H., Doyle, Andrew
Publicado 2021

EPCAM and TROP2 share a role in claudin stabilization and development of intestinal and extraintestinal epithelia in mice

por Szabo, Roman, Ward, Jerrold M., Artunc, Ferruh, Bugge, Thomas H.
Publicado 2022

Accelerated Wound Healing by mTOR Activation in Genetically Defined Mouse Models

por Squarize, Cristiane H., Castilho, Rogerio M., Bugge, Thomas H., Gutkind, J. Silvio
Publicado 2010

Regulation of Feto-Maternal Barrier by Matriptase- and PAR-2-Mediated Signaling Is Required for Placental Morphogenesis and Mouse Embryonic Survival

por Szabo, Roman, Peters, Diane E., Kosa, Peter, Camerer, Eric, Bugge, Thomas H.
Publicado 2014

Anti-tumor activity of anthrax toxin variants that form a functional translocation pore by intermolecular complementation

por Liu, Shihui, Ma, Qian, Fattah, Rasem, Bugge, Thomas H., Leppla, Stephen H.
Publicado 2017

Matriptase promotes inflammatory cell accumulation and progression of established epidermal tumors

por Sales, Katiuchia Uzzun, Friis, Stine, Abusleme, Loreto, Moutsopoulos, Niki M., Bugge, Thomas H.
Publicado 2014

Loss of proteolytically processed filaggrin caused by epidermal deletion of Matriptase/MT-SP1

por List, Karin, Szabo, Roman, Wertz, Philip W., Segre, Julie, Haudenschild, Christian C., Kim, Soo-Youl, Bugge, Thomas H.
Publicado 2003

Efficient Targeting of Head and Neck Squamous Cell Carcinoma by Systemic Administration of a Dual uPA and MMP-Activated Engineered Anthrax Toxin

por Schafer, Jeffrey M., Peters, Diane E., Morley, Thomas, Liu, Shihui, Molinolo, Alfredo A., Leppla, Stephen H., Bugge, Thomas H.
Publicado 2011

Matriptase zymogen supports epithelial development, homeostasis and regeneration

por Friis, Stine, Tadeo, Daniel, Le-Gall, Sylvain M., Jürgensen, Henrik Jessen, Sales, Katiuchia Uzzun, Camerer, Eric, Bugge, Thomas H.
Publicado 2017

A potent tumor-selective ERK pathway inactivator with high therapeutic index

por Zuo, Zehua, Liu, Jie, Sun, Zhihao, Silverstein, Rachel, Zou, Meijuan, Finkel, Toren, Bugge, Thomas H, Leppla, Stephen H, Liu, Shihui
Publicado 2022

Kidney-Specific Membrane-Bound Serine Proteases CAP1/Prss8 and CAP3/St14 Affect ENaC Subunit Abundances but Not Its Activity

por Ehret, Elodie, Stroh, Sévan, Auberson, Muriel, Ino, Frédérique, Jäger, Yannick, Maillard, Marc, Szabo, Roman, Bugge, Thomas H., Frateschi, Simona, Hummler, Edith
Publicado 2023

ERK and c-Myc signaling in host-derived tumor endothelial cells is essential for solid tumor growth

por Zuo, Zehua, Liu, Jie, Sun, Zhihao, Cheng, Yu-Wei, Ewing, Michael, Bugge, Thomas H., Finkel, Toren, Leppla, Stephen H., Liu, Shihui
Publicado 2022

Matriptase initiates epidermal prokallikrein activation and disease onset in a mouse model of Netherton syndrome

por Sales, Katiuchia Uzzun, Masedunskas, Andrius, Bey, Alexandra L., Rasmussen, Amber, Weigert, Roberto, List, Karin, Szabo, Roman, Overbeek, Paul A., Bugge, Thomas H.
Publicado 2010

c-Met-induced epithelial carcinogenesis is initiated by the serine protease matriptase

por Szabo, Roman, Rasmussen, Amber L., Moyer, Amanda B., Kosa, Peter, Schafer, Jeffrey M., Molinolo, Alfredo A., Gutkind, J. Silvio, Bugge, Thomas H.
Publicado 2011