CDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD

por Bukanov, Nikolay O., Moreno, Sarah E., Natoli, Thomas A., Rogers, Kelly A., Smith, Laurie A., Ledbetter, Steven R., Oumata, Nassima, Galons, Hervé, Meijer, Laurent, Ibraghimov-Beskrovnaya, Oxana
Publicado 2012

Differences in the timing and magnitude of Pkd1 gene deletion determine the severity of polycystic kidney disease in an orthologous mouse model of ADPKD

por Rogers, Kelly A., Moreno, Sarah E., Smith, Laurie A., Husson, Hervé, Bukanov, Nikolay O., Ledbetter, Steven R., Budman, Yeva, Lu, Yuefeng, Wang, Bing, Ibraghimov‐Beskrovnaya, Oxana, Natoli, Thomas A.
Publicado 2016

Loss of GM3 synthase gene, but not sphingosine kinase 1, is protective against murine nephronophthisis-related polycystic kidney disease

por Natoli, Thomas A., Husson, Hervé, Rogers, Kelly A., Smith, Laurie A., Wang, Bing, Budman, Yeva, Bukanov, Nikolay O., Ledbetter, Steven R., Klinger, Katherine W., Leonard, John P., Ibraghimov-Beskrovnaya, Oxana
Publicado 2012

Anti-microRNA-21 Therapy on Top of ACE Inhibition Delays Renal Failure in Alport Syndrome Mouse Models

por Rubel, Diana, Boulanger, Joseph, Craciun, Florin, Xu, Ethan Y., Zhang, Yanqin, Phillips, Lucy, Callahan, Michelle, Weber, William, Song, Wenping, Ngai, Nicholas, Bukanov, Nikolay O., Shi, Xingyi, Hariri, Ali, Husson, Hervé, Ibraghimov-Beskrovnaya, Oxana, Liu, Shiguang, Gross, Oliver
Publicado 2022

Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis

por Husson, Hervé, Moreno, Sarah, Smith, Laurie A., Smith, Mandy M., Russo, Ryan J., Pitstick, Rose, Sergeev, Mikhail, Ledbetter, Steven R., Bukanov, Nikolay O., Lane, Monica, Zhang, Kate, Billot, Katy, Carlson, George, Shah, Jagesh, Meijer, Laurent, Beier, David R., Ibraghimov-Beskrovnaya, Oxana
Publicado 2016

Correction of cilia structure and function alleviates multi-organ pathology in Bardet–Biedl syndrome mice

por Husson, Hervé, Bukanov, Nikolay O, Moreno, Sarah, Smith, Mandy M, Richards, Brenda, Zhu, Cheng, Picariello, Tyler, Park, Hyejung, Wang, Bing, Natoli, Thomas A, Smith, Laurie A, Zanotti, Stefano, Russo, Ryan J, Madden, Stephen L, Klinger, Katherine W, Modur, Vijay, Ibraghimov-Beskrovnaya, Oxana
Publicado 2020