A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen

por Bianchi, Valentina, Bulek, Anna, Fuller, Anna, Lloyd, Angharad, Attaf, Meriem, Rizkallah, Pierre J., Dolton, Garry, Sewell, Andrew K., Cole, David K.
Publicado 2016

TCR/pMHC Optimized Protein crystallization Screen

por Bulek, Anna M., Madura, Florian, Fuller, Anna, Holland, Christopher J., Schauenburg, Andrea J.A., Sewell, Andrew K., Rizkallah, Pierre J., Cole, David K.
Publicado 2012

Structural basis for ineffective T-cell responses to MHC anchor residue-improved “heteroclitic” peptides

por Madura, Florian, Rizkallah, Pierre J, Holland, Christopher J, Fuller, Anna, Bulek, Anna, Godkin, Andrew J, Schauenburg, Andrea J, Cole, David K, Sewell, Andrew K
Publicado 2015

Human β-Cell Killing by Autoreactive Preproinsulin-Specific CD8 T Cells Is Predominantly Granule-Mediated With the Potency Dependent Upon T-Cell Receptor Avidity

por Knight, Robin R., Kronenberg, Deborah, Zhao, Min, Huang, Guo Cai, Eichmann, Martin, Bulek, Anna, Wooldridge, Linda, Cole, David K., Sewell, Andrew K., Peakman, Mark, Skowera, Ania
Publicado 2013

T cell receptor alpha variable 12‐2 bias in the immunodominant response to Yellow fever virus

por Bovay, Amandine, Zoete, Vincent, Dolton, Garry, Bulek, Anna M., Cole, David K., Rizkallah, Pierre J., Fuller, Anna, Beck, Konrad, Michielin, Olivier, Speiser, Daniel E., Sewell, Andrew K., Fuertes Marraco, Silvia A.
Publicado 2017

In Silico and Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility

por Holland, Christopher J., MacLachlan, Bruce J., Bianchi, Valentina, Hesketh, Sophie J., Morgan, Richard, Vickery, Owen, Bulek, Anna M., Fuller, Anna, Godkin, Andrew, Sewell, Andrew K., Rizkallah, Pierre J., Wells, Stephen, Cole, David K.
Publicado 2018

Genetic and Structural Basis for Selection of a Ubiquitous T Cell Receptor Deployed in Epstein-Barr Virus Infection

por Miles, John J., Bulek, Anna M., Cole, David K., Gostick, Emma, Schauenburg, Andrea J. A., Dolton, Garry, Venturi, Vanessa, Davenport, Miles P., Tan, Mai Ping, Burrows, Scott R., Wooldridge, Linda, Price, David A., Rizkallah, Pierre J., Sewell, Andrew K.
Publicado 2010

Exploration of T cell immune responses by expression of a dominant-negative SHP1 and SHP2

por Taylor, Julia, Bulek, Anna, Gannon, Isaac, Robson, Mathew, Kokalaki, Evangelia, Grothier, Thomas, McKenzie, Callum, El-Kholy, Mohamed, Stavrou, Maria, Traynor-White, Charlotte, Lim, Wen Chean, Panagiotou, Panagiota, Srivastava, Saket, Baldan, Vania, Sillibourne, James, Ferrari, Mathieu, Pule, Martin, Thomas, Simon
Publicado 2023

Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity

por Cole, David K., Bulek, Anna M., Dolton, Garry, Schauenberg, Andrea J., Szomolay, Barbara, Rittase, William, Trimby, Andrew, Jothikumar, Prithiviraj, Fuller, Anna, Skowera, Ania, Rossjohn, Jamie, Zhu, Cheng, Miles, John J., Peakman, Mark, Wooldridge, Linda, Rizkallah, Pierre J., Sewell, Andrew K.
Publicado 2016

T-cell Receptor Specificity Maintained by Altered Thermodynamics

por Madura, Florian, Rizkallah, Pierre J., Miles, Kim M., Holland, Christopher J., Bulek, Anna M., Fuller, Anna, Schauenburg, Andrea J. A., Miles, John J., Liddy, Nathaniel, Sami, Malkit, Li, Yi, Hossain, Moushumi, Baker, Brian M., Jakobsen, Bent K., Sewell, Andrew K., Cole, David K.
Publicado 2013

Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope

por Cole, David K., Fuller, Anna, Dolton, Garry, Zervoudi, Efthalia, Legut, Mateusz, Miles, Kim, Blanchfield, Lori, Madura, Florian, Holland, Christopher J., Bulek, Anna M., Bridgeman, John S., Miles, John J., Schauenburg, Andrea J. A., Beck, Konrad, Evavold, Brian D., Rizkallah, Pierre J., Sewell, Andrew K.
Publicado 2017

T-cell Receptor (TCR)-Peptide Specificity Overrides Affinity-enhancing TCR-Major Histocompatibility Complex Interactions

por Cole, David K., Miles, Kim M., Madura, Florian, Holland, Christopher J., Schauenburg, Andrea J. A., Godkin, Andrew J., Bulek, Anna M., Fuller, Anna, Akpovwa, Hephzibah J. E., Pymm, Phillip G., Liddy, Nathaniel, Sami, Malkit, Li, Yi, Rizkallah, Pierre J., Jakobsen, Bent K., Sewell, Andrew K.
Publicado 2014

Structural Mechanism Underpinning Cross-reactivity of a CD8(+) T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase

por Cole, David K., van den Berg, Hugo A., Lloyd, Angharad, Crowther, Michael D., Beck, Konrad, Ekeruche-Makinde, Julia, Miles, John J., Bulek, Anna M., Dolton, Garry, Schauenburg, Andrea J., Wall, Aaron, Fuller, Anna, Clement, Mathew, Laugel, Bruno, Rizkallah, Pierre J., Wooldridge, Linda, Sewell, Andrew K.
Publicado 2017

TCR‐induced alteration of primary MHC peptide anchor residue

por Madura, Florian, Rizkallah, Pierre J., Legut, Mateusz, Holland, Christopher J., Fuller, Anna, Bulek, Anna, Schauenburg, Andrea J., Trimby, Andrew, Hopkins, Jade R., Wells, Stephen A., Godkin, Andrew, Miles, John J., Sami, Malkit, Li, Yi, Liddy, Nathaniel, Jakobsen, Bent K., Loveridge, E. Joel, Cole, David K., Sewell, Andrew K.
Publicado 2019

Structural basis of human β-cell killing by CD8(+) T cells in Type 1 diabetes

por Bulek, Anna M., Cole, David K., Skowera, Ania, Dolton, Garry, Gras, Stephanie, Madura, Florian, Fuller, Anna, Miles, John J., Gostick, Emma, Price, David A., Drijfhout, Jan W., Knight, Robin R., Huang, Guo C., Lissin, Nikolai, Molloy, Peter E., Wooldridge, Linda, Jakobsen, Bent K., Rossjohn, Jamie, Peakman, Mark, Rizkallah, Pierre J., Sewell, Andrew K.
Publicado 2012