Bordetella Adenylate Cyclase Toxin Mobilizes Its β(2) Integrin Receptor into Lipid Rafts to Accomplish Translocation across Target Cell Membrane in Two Steps

por Bumba, Ladislav, Masin, Jiri, Fiser, Radovan, Sebo, Peter
Publicado 2010

Bordetella pertussis and Bordetella bronchiseptica filamentous hemagglutinins are processed at different sites

por Jurnecka, David, Man, Petr, Sebo, Peter, Bumba, Ladislav
Publicado 2018

Bordetella Pertussis Adenylate Cyclase Toxin Does Not Possess a Phospholipase A Activity; Serine 606 and Aspartate 1079 Residues Are Not Involved in Target Cell Delivery of the Ade...

por Bumba, Ladislav, Masin, Jiri, Osickova, Adriana, Osicka, Radim, Sebo, Peter
Publicado 2018

The adenylate cyclase toxin RTX domain follows a series templated folding mechanism with implications for toxin activity

por Chen, Guojun, Wang, Han, Bumba, Ladislav, Masin, Jiri, Sebo, Peter, Li, Hongbin
Publicado 2023

Bordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3

por Osicka, Radim, Osickova, Adriana, Hasan, Shakir, Bumba, Ladislav, Cerny, Jiri, Sebo, Peter
Publicado 2015

Poly-N-Acetyllactosamine Neo-Glycoproteins as Nanomolar Ligands of Human Galectin-3: Binding Kinetics and Modeling

por Bumba, Ladislav, Laaf, Dominic, Spiwok, Vojtěch, Elling, Lothar, Křen, Vladimír, Bojarová, Pavla
Publicado 2018

Heterologous expression of full-length capsid protein of porcine circovirus 2 in Escherichia coli and its potential use for detection of antibodies

por Marcekova, Zuzana, Psikal, Ivan, Kosinova, Eva, Benada, Oldrich, Sebo, Peter, Bumba, Ladislav
Publicado 2009

Lipid binding by the N-terminal motif mediates plasma membrane localization of Bordetella effector protein BteA

por Malcova, Ivana, Bumba, Ladislav, Uljanic, Filip, Kuzmenko, Darya, Nedomova, Jana, Kamanova, Jana
Publicado 2021

Integrative Binding Sites within Intracellular Termini of TRPV1 Receptor

por Grycova, Lenka, Holendova, Blanka, Bumba, Ladislav, Bily, Jan, Jirku, Michaela, Lansky, Zdenek, Teisinger, Jan
Publicado 2012

BopN is a Gatekeeper of the Bordetella Type III Secretion System

por Navarrete, Kevin Munoz, Bumba, Ladislav, Prudnikova, Tatyana, Malcova, Ivana, Allsop, Tania Romero, Sebo, Peter, Kamanova, Jana
Publicado 2023

The conserved tyrosine residue 940 plays a key structural role in membrane interaction of Bordetella adenylate cyclase toxin

por Masin, Jiri, Roderova, Jana, Osickova, Adriana, Novak, Petr, Bumba, Ladislav, Fiser, Radovan, Sebo, Peter, Osicka, Radim
Publicado 2017

Structure–Function Relationships Underlying the Capacity of Bordetella Adenylate Cyclase Toxin to Disarm Host Phagocytes

por Novak, Jakub, Cerny, Ondrej, Osickova, Adriana, Linhartova, Irena, Masin, Jiri, Bumba, Ladislav, Sebo, Peter, Osicka, Radim
Publicado 2017

Pertussis toxin suppresses dendritic cell-mediated delivery of B. pertussis into lung-draining lymph nodes

por Klimova, Nela, Holubova, Jana, Streparola, Gaia, Tomala, Jakub, Brazdilova, Ludmila, Stanek, Ondrej, Bumba, Ladislav, Sebo, Peter
Publicado 2022

Acellular Pertussis Vaccine Inhibits Bordetella pertussis Clearance from the Nasal Mucosa of Mice

por Holubová, Jana, Staněk, Ondřej, Brázdilová, Ludmila, Mašín, Jiří, Bumba, Ladislav, Gorringe, Andrew R., Alexander, Frances, Šebo, Peter
Publicado 2020

Negatively charged residues of the segment linking the enzyme and cytolysin moieties restrict the membrane-permeabilizing capacity of adenylate cyclase toxin

por Masin, Jiri, Osickova, Adriana, Sukova, Anna, Fiser, Radovan, Halada, Petr, Bumba, Ladislav, Linhartova, Irena, Osicka, Radim, Sebo, Peter
Publicado 2016

Structural Basis of Ca(2+)-Dependent Self-Processing Activity of Repeat-in-Toxin Proteins

por Kuban, Vojtech, Macek, Pavel, Hritz, Jozef, Nechvatalova, Katerina, Nedbalcova, Katerina, Faldyna, Martin, Sebo, Peter, Zidek, Lukas, Bumba, Ladislav
Publicado 2020

Almost half of the RTX domain is dispensable for complement receptor 3 binding and cell-invasive activity of the Bordetella adenylate cyclase toxin

por Espinosa-Vinals, Carlos Angel, Masin, Jiri, Holubova, Jana, Stanek, Ondrej, Jurnecka, David, Osicka, Radim, Sebo, Peter, Bumba, Ladislav
Publicado 2021

Structural basis of the interaction between the putative adhesion-involved and iron-regulated FrpD and FrpC proteins of Neisseria meningitidis

por Sviridova, Ekaterina, Rezacova, Pavlina, Bondar, Alexey, Veverka, Vaclav, Novak, Petr, Schenk, Gundolf, Svergun, Dmitri I., Kuta Smatanova, Ivana, Bumba, Ladislav
Publicado 2017

Production of Highly Active Recombinant Dermonecrotic Toxin of Bordetella Pertussis

por Stanek, Ondrej, Linhartova, Irena, Holubova, Jana, Bumba, Ladislav, Gardian, Zdenko, Malandra, Anna, Bockova, Barbora, Teruya, Shihono, Horiguchi, Yasuhiko, Osicka, Radim, Sebo, Peter
Publicado 2020

RTX proteins: a highly diverse family secreted by a common mechanism

por Linhartová, Irena, Bumba, Ladislav, Mašín, Jiří, Basler, Marek, Osička, Radim, Kamanová, Jana, Procházková, Kateřina, Adkins, Irena, Hejnová-Holubová, Jana, Sadílková, Lenka, Morová, Jana, Šebo, Peter
Publicado 2010