gPKPDSim: a SimBiology(®)-based GUI application for PKPD modeling in drug development

por Hosseini, Iraj, Gajjala, Anita, Bumbaca Yadav, Daniela, Sukumaran, Siddharth, Ramanujan, Saroja, Paxson, Ricardo, Gadkar, Kapil
Publicado 2018

Trastuzumab does not bind rat or mouse ErbB2/neu: implications for selection of non-clinical safety models for trastuzumab-based therapeutics

por Lewis Phillips, Gail, Guo, Jun, Kiefer, James R., Proctor, William, Bumbaca Yadav, Daniela, Dybdal, Noel, Shen, Ben-Quan
Publicado 2021

PBPK-PD modeling for the preclinical development and clinical translation of tau antibodies for Alzheimer’s disease

por Bloomingdale, Peter, Bumbaca-Yadav, Daniela, Sugam, Jonathan, Grauer, Steve, Smith, Brad, Antonenko, Svetlana, Judo, Michael, Azadi, Glareh, Yee, Ka Lai
Publicado 2022

Complex formation of anti‐VEGF‐C with VEGF‐C released during blood coagulation resulted in an artifact in its serum pharmacokinetics

por Bumbaca Yadav, Daniela, Reyes, Arthur E., Gupta, Priyanka, Vernes, Jean‐Michel, Meng, Y. Gloria, Schweiger, Michelle G., Stainton, Shannon L., Fuh, Germaine, Fielder, Paul J., Kamath, Amrita V., Shen, Ben‐Quan
Publicado 2020

Evaluation and use of an anti‐cynomolgus monkey CD79b surrogate antibody–drug conjugate to enable clinical development of polatuzumab vedotin

por Li, Dongwei, Lee, Donna, Dere, Randall C., Zheng, Bing, Yu, Shang‐Fan, Fuh, Franklin K., Kozak, Katherine R., Chung, Shan, Bumbaca Yadav, Daniela, Nazzal, Denise, Danilenko, Dimitry, Go, Mary Ann T., Williams, Marna, Polson, Andrew G., Poon, Kirsten Achilles, Prabhu, Saileta
Publicado 2019