Chemoenzymatic Synthesis and Pharmacological Characterization of Functionalized Aspartate Analogues As Novel Excitatory Amino Acid Transporter Inhibitors

por Fu, Haigen, Zhang, Jielin, Tepper, Pieter G., Bunch, Lennart, Jensen, Anders A., Poelarends, Gerrit J.
Publicado 2018

Structure-activity-relationship study of N-acyl-N-phenylpiperazines as potential inhibitors of the Excitatory Amino Acid Transporters (EAATs): improving the potency of a micromolar...

por Huynh, Tri HV, Demmer, Charles S, Abrahamsen, Bjarke, Marcher, Emil, Frykman, Mikael, Jensen, Anders A, Bunch, Lennart
Publicado 2013

Discovery of (R)-2-amino-3-triazolpropanoic acid derivatives as NMDA receptor glycine site agonists with GluN2 subunit-specific activity

por Zhao, Fabao, Mazis, Georgios, Yi, Feng, Lotti, James S., Layeux, Michael S., Schultz, Eric P., Bunch, Lennart, Hansen, Kasper B., Clausen, Rasmus P.
Publicado 2022

The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells

por Pedraz-Cuesta, Elena, Christensen, Sandra, Jensen, Anders A., Jensen, Niels Frank, Bunch, Lennart, Romer, Maria Unni, Brünner, Nils, Stenvang, Jan, Pedersen, Stine Falsig
Publicado 2015