Site-Specific Considerations on Engineered T Cells for Malignant Gliomas

por Elmadany, Nirmeen, Alhalabi, Obada T., Platten, Michael, Bunse, Lukas
Publicado 2022

Genetically Modified Cellular Therapies for Malignant Gliomas

por Kilian, Michael, Bunse, Theresa, Wick, Wolfgang, Platten, Michael, Bunse, Lukas
Publicado 2021

Clinical and Translational Advances in Glioma Immunotherapy

por Bunse, Lukas, Bunse, Theresa, Krämer, Christopher, Chih, Yu-Chan, Platten, Michael
Publicado 2022

K27M-mutant histone-3 as a novel target for glioma immunotherapy

por Ochs, Katharina, Ott, Martina, Bunse, Theresa, Sahm, Felix, Bunse, Lukas, Deumelandt, Katrin, Sonner, Jana K., Keil, Melanie, von Deimling, Andreas, Wick, Wolfgang, Platten, Michael
Publicado 2017

Common T-Cell-Receptor Motifs and Features in Patients with Cytomegalovirus (CMV)-Seronegative End-Stage Renal Disease Receiving a Peptide Vaccination against CMV

por Bunse, Lukas, Sommerer, Claudia, Tan, Chin Leng, Korell, Felix, Schmitt, Anita, Hückelhoven-Krauss, Angela, Neuber, Brigitte, Mertens, Thomas, Platten, Michael, Green, Edward W., Zeier, Martin, Schmitt, Michael
Publicado 2022

Intrathecal activation of CD8(+) memory T cells in IgG4‐related disease of the brain parenchyma

por Friedrich, Mirco, Kehl, Niklas, Engelke, Niko, Kraus, Josephine, Lindner, Katharina, Münch, Philipp, Mildenberger, Iris, Groden, Christoph, Gass, Achim, Etminan, Nima, Fatar, Marc, von Deimling, Andreas, Reuss, David, Platten, Michael, Bunse, Lukas
Publicado 2021

Dysfunctional dendritic cells limit antigen-specific T cell response in glioma

por Friedrich, Mirco, Hahn, Markus, Michel, Julius, Sankowski, Roman, Kilian, Michael, Kehl, Niklas, Günter, Manina, Bunse, Theresa, Pusch, Stefan, von Deimling, Andreas, Wick, Wolfgang, Autenrieth, Stella E, Prinz, Marco, Platten, Michael, Bunse, Lukas
Publicado 2022

Comparative evaluation of T-cell receptors in experimental glioma-draining lymph nodes

por Blobner, Jens, Kilian, Michael, Tan, Chin Leng, Aslan, Katrin, Sanghvi, Khwab, Meyer, Jochen, Fischer, Manuel, Jähne, Kristine, Breckwoldt, Michael O, Sahm, Felix, von Deimling, Andreas, Bendszus, Martin, Wick, Wolfgang, Platten, Michael, Green, Edward, Bunse, Lukas
Publicado 2021

A Set of Cell Lines Derived from a Genetic Murine Glioblastoma Model Recapitulates Molecular and Morphological Characteristics of Human Tumors

por Costa, Barbara, Fletcher, Michael N. C., Boskovic, Pavle, Ivanova, Ekaterina L., Eisemann, Tanja, Lohr, Sabrina, Bunse, Lukas, Löwer, Martin, Burchard, Stefanie, Korshunov, Andrey, Coltella, Nadia, Cusimano, Melania, Naldini, Luigi, Liu, Hai-Kun, Platten, Michael, Radlwimmer, Bernhard, Angel, Peter, Peterziel, Heike
Publicado 2021

AMPLIFY-NEOVAC: a randomized, 3-arm multicenter phase I trial to assess safety, tolerability and immunogenicity of IDH1-vac combined with an immune checkpoint inhibitor targeting p...

por Bunse, Lukas, Rupp, Anne-Kathleen, Poschke, Isabel, Bunse, Theresa, Lindner, Katharina, Wick, Antje, Blobner, Jens, Misch, Martin, Tabatabai, Ghazaleh, Glas, Martin, Schnell, Oliver, Gempt, Jens, Denk, Monika, Reifenberger, Guido, Bendszus, Martin, Wuchter, Patrick, Steinbach, Joachim P, Wick, Wolfgang, Platten, Michael
Publicado 2022

Patient-Derived Tumor Organoids for Guidance of Personalized Drug Therapies in Recurrent Glioblastoma

por Ratliff, Miriam, Kim, Hichul, Qi, Hao, Kim, Minsung, Ku, Bosung, Azorin, Daniel Dominguez, Hausmann, David, Khajuria, Rajiv K., Patel, Areeba, Maier, Elena, Cousin, Loic, Ogier, Arnaud, Sahm, Felix, Etminan, Nima, Bunse, Lukas, Winkler, Frank, El-Khoury, Victoria, Platten, Michael, Kwon, Yong-Jun
Publicado 2022

T-cell Receptor Therapy Targeting Mutant Capicua Transcriptional Repressor in Experimental Gliomas

por Kilian, Michael, Friedrich, Mirco, Sanghvi, Khwab, Green, Edward, Pusch, Stefan, Kawauchi, Daisuke, Löwer, Martin, Sonner, Jana K., Krämer, Christopher, Zaman, Julia, Jung, Stefanie, Breckwoldt, Michael O., Willimsky, Gerald, Eichmüller, Stefan B., von Deimling, Andreas, Wick, Wolfgang, Sahm, Felix, Platten, Michael, Bunse, Lukas
Publicado 2022

T cell receptor dynamic and transcriptional determinants of T cell expansion in glioma-infiltrating T cells

por Lu, Kevin Hai-Ning, Michel, Julius, Kilian, Michael, Aslan, Katrin, Qi, Hao, Kehl, Niklas, Jung, Stefanie, Sanghvi, Khwab, Lindner, Katharina, Zhang, Xin-Wen, Green, Edward W, Poschke, Isabel, Ratliff, Miriam, Bunse, Theresa, Sahm, Felix, von Deimling, Andreas, Wick, Wolfgang, Platten, Michael, Bunse, Lukas
Publicado 2022

In vivo nanoparticle-based T cell imaging can predict therapy response towards adoptive T cell therapy in experimental glioma

por Hunger, Jessica, Schregel, Katharina, Boztepe, Berin, Agardy, Dennis Alexander, Turco, Verena, Karimian-Jazi, Kianush, Weidenfeld, Ina, Streibel, Yannik, Fischer, Manuel, Sturm, Volker, Santarella-Mellwig, Rachel, Kilian, Michael, Jähne, Kristine, Sahm, Katharina, Wick, Wolfgang, Bunse, Lukas, Heiland, Sabine, Bunse, Theresa, Bendszus, Martin, Platten, Michael, Breckwoldt, Michael O.
Publicado 2023

IgE type multiple myeloma exhibits hypermutated phenotype and tumor reactive T cells

por Kehl, Niklas, Kilian, Michael, Michel, Julius, Wagner, Tim R, Uhrig, Sebastian, Brobeil, Alexander, Sester, Lilli-Sophie, Blobner, Sven, Steiger, Simon, Hundemer, Michael, Weinhold, Niels, Rippe, Karsten, Fröhling, Stefan, Eichmüller, Stefan B, Bunse, Lukas, Müller-Tidow, Carsten, Goldschmidt, Hartmut, Platten, Michael, Raab, Marc-Steffen, Friedrich, Mirco J
Publicado 2022

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and CNS inflammation via the aryl hydrocarbon receptor

por Rothhammer, Veit, Mascanfroni, Ivan D., Bunse, Lukas, Takenaka, Maisa C., Kenison, Jessica E., Mayo, Lior, Chao, Chun-Cheih, Patel, Bonny, Yan, Raymond, Blain, Manon, Alvarez, Jorge I., Kébir, Hania, Anandasabapathy, Niroshana, Izquierdo, Guillermo, Jung, Steffen, Obholzer, Nikolaus, Pochet, Nathalie, Clish, Clary B., Prinz, Marco, Prat, Alexandre, Antel, Jack, Quintana, Francisco J.
Publicado 2016

INTERCEPT H3: a multicenter phase I peptide vaccine trial for the treatment of H3-mutated diffuse midline gliomas

por Grassl, Niklas, Sahm, Katharina, Süße, Heike, Poschke, Isabel, Bunse, Lukas, Bunse, Theresa, Boschert, Tamara, Mildenberger, Iris, Rupp, Anne-Kathleen, Ewinger, Max Philipp, Lanz, Lisa-Marie, Denk, Monika, Tabatabai, Ghazaleh, Ronellenfitsch, Michael W., Herrlinger, Ulrich, Glas, Martin, Krex, Dietmar, Vajkoczy, Peter, Wick, Antje, Harting, Inga, Sahm, Felix, von Deimling, Andreas, Bendszus, Martin, Wick, Wolfgang, Platten, Michael
Publicado 2023

A H3K27M-targeted vaccine in adults with diffuse midline glioma

por Grassl, Niklas, Poschke, Isabel, Lindner, Katharina, Bunse, Lukas, Mildenberger, Iris, Boschert, Tamara, Jähne, Kristine, Green, Edward W., Hülsmeyer, Ingrid, Jünger, Simone, Kessler, Tobias, Suwala, Abigail K., Eisele, Philipp, Breckwoldt, Michael O., Vajkoczy, Peter, Grauer, Oliver M., Herrlinger, Ulrich, Tonn, Joerg-Christian, Denk, Monika, Sahm, Felix, Bendszus, Martin, von Deimling, Andreas, Winkler, Frank, Wick, Wolfgang, Platten, Michael, Sahm, Katharina
Publicado 2023

A vaccine targeting mutant IDH1 in newly diagnosed glioma

por Platten, Michael, Bunse, Lukas, Wick, Antje, Bunse, Theresa, Le Cornet, Lucian, Harting, Inga, Sahm, Felix, Sanghvi, Khwab, Tan, Chin Leng, Poschke, Isabel, Green, Edward, Justesen, Sune, Behrens, Geoffrey A., Breckwoldt, Michael O., Freitag, Angelika, Rother, Lisa-Marie, Schmitt, Anita, Schnell, Oliver, Hense, Jörg, Misch, Martin, Krex, Dietmar, Stevanovic, Stefan, Tabatabai, Ghazaleh, Steinbach, Joachim P., Bendszus, Martin, von Deimling, Andreas, Schmitt, Michael, Wick, Wolfgang
Publicado 2021

Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas

por Aslan, Katrin, Turco, Verena, Blobner, Jens, Sonner, Jana K., Liuzzi, Anna Rita, Núñez, Nicolás Gonzalo, De Feo, Donatella, Kickingereder, Philipp, Fischer, Manuel, Green, Ed, Sadik, Ahmed, Friedrich, Mirco, Sanghvi, Khwab, Kilian, Michael, Cichon, Frederik, Wolf, Lara, Jähne, Kristine, von Landenberg, Anna, Bunse, Lukas, Sahm, Felix, Schrimpf, Daniel, Meyer, Jochen, Alexander, Allen, Brugnara, Gianluca, Röth, Ralph, Pfleiderer, Kira, Niesler, Beate, von Deimling, Andreas, Opitz, Christiane, Breckwoldt, Michael O., Heiland, Sabine, Bendszus, Martin, Wick, Wolfgang, Becher, Burkhard, Platten, Michael
Publicado 2020