Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites

por Wu, Qian, Paul, Atanu, Su, Dan, Mehmood, Shahid, Foo, Tzeh Keong, Ochi, Takashi, Bunting, Emma L., Xia, Bing, Robinson, Carol V., Wang, Bin, Blundell, Tom L.
Publicado 2016

FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington’s disease

por Goold, Robert, Hamilton, Joseph, Menneteau, Thomas, Flower, Michael, Bunting, Emma L., Aldous, Sarah G., Porro, Antonio, Vicente, José R., Allen, Nicholas D., Wilkinson, Hilary, Bates, Gillian P., Sartori, Alessandro A., Thalassinos, Konstantinos, Balmus, Gabriel, Tabrizi, Sarah J.
Publicado 2021

A neurodegeneration checkpoint mediated by REST protects against the onset of Alzheimer’s disease

por Aron, Liviu, Qiu, Chenxi, Ngian, Zhen Kai, Liang, Marianna, Drake, Derek, Choi, Jaejoon, Fernandez, Marty A., Roche, Perle, Bunting, Emma L., Lacey, Ella K., Hamplova, Sara E., Yuan, Monlan, Wolfe, Michael S., Bennett, David A., Lee, Eunjung A., Yankner, Bruce A.
Publicado 2023

Sequence of clinical and neurodegeneration events in Parkinson’s disease progression

por Oxtoby, Neil P, Leyland, Louise-Ann, Aksman, Leon M, Thomas, George E C, Bunting, Emma L, Wijeratne, Peter A, Young, Alexandra L, Zarkali, Angelika, Tan, Manuela M X, Bremner, Fion D, Keane, Pearse A, Morris, Huw R, Schrag, Anette E, Alexander, Daniel C, Weil, Rimona S
Publicado 2021