Sample Preparation and Extraction in Small Sample Volumes Suitable for Pediatric Clinical Studies: Challenges, Advances, and Experiences of a Bioanalytical HPLC-MS/MS Method Valida...

por Burckhardt, Bjoern B., Laeer, Stephanie
Publicado 2015

Potential and Limitations of Atrial Natriuretic Peptide as Biomarker in Pediatric Heart Failure—A Comparative Review

por Gangnus, Tanja, Burckhardt, Bjoern B.
Publicado 2019

Sensitive mass spectrometric determination of kinin-kallikrein system peptides in light of COVID-19

por Gangnus, Tanja, Burckhardt, Bjoern B.
Publicado 2021

Targeted LC-MS/MS platform for the comprehensive determination of peptides in the kallikrein-kinin system

por Gangnus, Tanja, Burckhardt, Bjoern B.
Publicado 2021

Reliable measurement of plasma kinin peptides: Importance of preanalytical variables

por Gangnus, Tanja, Burckhardt, Bjoern B.
Publicado 2022

Mass spectrometric study of variation in kinin peptide profiles in nasal fluids and plasma of adult healthy individuals

por Gangnus, Tanja, Bartel, Anke, Burckhardt, Bjoern B.
Publicado 2022

Model-dependent pharmacokinetic analysis of enalapril administered to healthy adult volunteers using orodispersible minitablets for use in pediatrics

por Faisal, Muhammad, Cawello, Willi, Burckhardt, Bjoern B, Laer, Stephanie
Publicado 2019

Self-Instruction Video Versus Face-to-Face Instruction of Pharmacy Students’ Skills in Blood Pressure Measurement

por Farahani, Samieh, Farahani, Imaneh, Burckhardt, Bjoern B., Schwender, Holger, Laeer, Stephanie
Publicado 2020

The Development of an Educational Video on Blood Pressure Measurement for Pharmacy Students

por Farahani, Samieh, Farahani, Imaneh, Burckhardt, Bjoern B, Monser, Karin, Laeer, Stephanie
Publicado 2021

Embedding a Sensitive Liquid-Core Waveguide UV Detector into an HPLC-UV System for Simultaneous Quantification of Differently Dosed Active Ingredients during Drug Release

por Chamberlain, Rebecca, Windolf, Hellen, Burckhardt, Bjoern B., Breitkreutz, Jörg, Fischer, Björn
Publicado 2022

Simultaneous Semi-Mechanistic Population Pharmacokinetic Modeling Analysis of Enalapril and Enalaprilat Serum and Urine Concentrations From Child Appropriate Orodispersible Minitab...

por Faisal, Muhammad, Cawello, Willi, Burckhardt, Bjoern B., de Hoon, Jan, Laer, Stephanie
Publicado 2019

Development and evaluation of a composite dosage form containing desmopressin acetate for buccal administration

por Kottke, Dina, Burckhardt, Bjoern B., Knaab, Tanja C., Breitkreutz, Jörg, Fischer, Björn
Publicado 2021

Formulation Development of Sublingual Cyclobenzaprine Tablets Empowered by Standardized and Physiologically Relevant Ex Vivo Permeation Studies

por Majid, Haidara, Puzik, Andreas, Maier, Tanja, Merk, Raphaela, Bartel, Anke, Mueller, Hans-Christian, Burckhardt, Bjoern B.
Publicado 2021

Picomolar Sensitivity Analysis of Multiple Bradykinin-Related Peptides in the Blood Plasma of Patients With Hereditary Angioedema in Remission: A Pilot Study

por Marceau, François, Rivard, Georges-Etienne, Hébert, Jacques, Gauthier, Julie, Bachelard, Hélène, Gangnus, Tanja, Burckhardt, Bjoern B.
Publicado 2022

Total Synthesis of the Antimycobacterial Natural Product Chlorflavonin and Analogs via a Late-Stage Ruthenium(II)-Catalyzed ortho-C(sp(2))-H-Hydroxylation

por Berger, Alexander, Knak, Talea, Kiffe-Delf, Anna-Lene, Mudrovcic, Korana, Singh, Vinayak, Njoroge, Mathew, Burckhardt, Bjoern B., Gopalswamy, Mohanraj, Lungerich, Beate, Ackermann, Lutz, Gohlke, Holger, Chibale, Kelly, Kalscheuer, Rainer, Kurz, Thomas
Publicado 2022

Simulation Training to Improve Informed Consent and Pharmacokinetic/Pharmacodynamic Sampling in Pediatric Trials

por Burckhardt, Bjoern B., Ciplea, Agnes Maria, Laven, Anna, Ablonczy, László, Klingmann, Ingrid, Läer, Stephanie, Kleine, Karl, Dalinghaus, Michiel, Đukić, Milan, Breur, Johannes M. P. J., van der Meulen, Marijke, Swoboda, Vanessa, Schwender, Holger, Lagler, Florian B.
Publicado 2020

Enalapril and Enalaprilat Pharmacokinetics in Children with Heart Failure Due to Dilated Cardiomyopathy and Congestive Heart Failure after Administration of an Orodispersible Enala...

por Laeer, Stephanie, Cawello, Willi, Burckhardt, Bjoern B., Ablonczy, László, Bajcetic, Milica, Breur, Johannes M. P. J., Dalinghaus, Michiel, Male, Christoph, de Wildt, Saskia N., Breitkreutz, Jörg, Faisal, Muhammed, Keatley-Clarke, Anne, Klingmann, Ingrid, Lagler, Florian B.
Publicado 2022

Orodispersible minitablets of enalapril for use in children with heart failure (LENA): Rationale and protocol for a multicentre pharmacokinetic bridging study and follow-up safety...

por Bajcetic, Milica, de Wildt, Saskia N., Dalinghaus, Michiel, Breitkreutz, Jörg, Klingmann, Ingrid, Lagler, Florian B., Keatley-Clarke, Anne, Breur, Johannes MPJ., Male, Christoph, Jovanovic, Ida, Szatmári, Andras, Ablonczy, László, Burckhardt, Bjoern B., Cawello, Willi, Kleine, Karl, Obarcanin, Emina, Spatenkova, Lucie, Swoboda, Vanessa, van der Meulen, Marijke, Wagner, Peter, Walsh, Jennifer, Läer, Stephanie
Publicado 2019

Dysregulation of the kallikrein-kinin system in bronchoalveolar lavage fluid of patients with severe COVID-19

por Martens, Caroline P., Van Mol, Pierre, Wauters, Joost, Wauters, Els, Gangnus, Tanja, Noppen, Bernard, Callewaert, Hanne, Feyen, Jean H.M., Liesenborghs, Laurens, Heylen, Elisabeth, Jansen, Sander, Pereira, Leydi Carolina Velásquez, Kraisin, Sirima, Guler, Ipek, Engelen, Matthias M., Ockerman, Anna, Van Herck, Anke, Vos, Robin, Vandenbriele, Christophe, Meersseman, Philippe, Hermans, Greet, Wilmer, Alexander, Martinod, Kimberly, Burckhardt, Bjoern B., Vanhove, Marc, Jacquemin, Marc, Verhamme, Peter, Neyts, Johan, Vanassche, Thomas
Publicado 2022