Toward an understanding of the structural basis of allostery in muscarinic acetylcholine receptors

por Burger, Wessel A.C., Sexton, Patrick M., Christopoulos, Arthur, Thal, David M.
Publicado 2018

Structure–Affinity Relationships and Structure–Kinetics Relationships of Pyrido[2,1-f]purine-2,4-dione Derivatives as Human Adenosine A(3) Receptor Antagonists

por Xia, Lizi, Burger, Wessel A. C., van Veldhoven, Jacobus P. D., Kuiper, Boaz J., van Duijl, Tirsa T., Lenselink, Eelke B., Paasman, Ellen, Heitman, Laura H., IJzerman, Adriaan P.
Publicado 2017

Author Correction: Structural basis of efficacy-driven ligand selectivity at GPCRs

por Powers, Alexander S., Pham, Vi, Burger, Wessel A. C., Thompson, Geoff, Laloudakis, Yianni, Barnes, Nicholas W., Sexton, Patrick M., Paul, Steven M., Christopoulos, Arthur, Thal, David M., Felder, Christian C., Valant, Celine, Dror, Ron O.
Publicado 2023

Structural basis of efficacy-driven ligand selectivity at GPCRs

por Powers, Alexander S., Pham, Vi, Burger, Wessel A. C., Thompson, Geoff, Laloudakis, Yianni, Barnes, Nicholas W., Sexton, Patrick M., Paul, Steven M., Christopoulos, Arthur, Thal, David M., Felder, Christian C., Valant, Celine, Dror, Ron O.
Publicado 2023

Xanomeline displays concomitant orthosteric and allosteric binding modes at the M(4) mAChR

por Burger, Wessel A. C., Pham, Vi, Vuckovic, Ziva, Powers, Alexander S., Mobbs, Jesse I., Laloudakis, Yianni, Glukhova, Alisa, Wootten, Denise, Tobin, Andrew B., Sexton, Patrick M., Paul, Steven M., Felder, Christian C., Danev, Radostin, Dror, Ron O., Christopoulos, Arthur, Valant, Celine, Thal, David M.
Publicado 2023

Crystal structure of the M(5) muscarinic acetylcholine receptor

por Vuckovic, Ziva, Gentry, Patrick R., Berizzi, Alice E., Hirata, Kunio, Varghese, Swapna, Thompson, Geoff, van der Westhuizen, Emma T., Burger, Wessel A. C., Rahmani, Raphaël, Valant, Celine, Langmead, Christopher J., Lindsley, Craig W., Baell, Jonathan B., Tobin, Andrew B., Sexton, Patrick M., Christopoulos, Arthur, Thal, David M.
Publicado 2019