Beyond PARP1: The Potential of Other Members of the Poly (ADP-Ribose) Polymerase Family in DNA Repair and Cancer Therapeutics

por Richard, Iain A., Burgess, Joshua T., O’Byrne, Kenneth J., Bolderson, Emma
Publicado 2022

PARP Inhibitors: Clinical Relevance, Mechanisms of Action and Tumor Resistance

por Rose, Maddison, Burgess, Joshua T., O’Byrne, Kenneth, Richard, Derek J., Bolderson, Emma
Publicado 2020

The role of inner nuclear membrane proteins in tumourigenesis and as potential targets for cancer therapy

por Rose, Maddison, Burgess, Joshua T., O’Byrne, Kenneth, Richard, Derek J., Bolderson, Emma
Publicado 2022

Epigenetic Mechanisms in DNA Double Strand Break Repair: A Clinical Review

por Fernandez, Alejandra, O’Leary, Connor, O’Byrne, Kenneth J, Burgess, Joshua, Richard, Derek J, Suraweera, Amila
Publicado 2021

Stochastic epithelial-mesenchymal transitions diversify non-cancerous lung cell behaviours

por Bhatia, Sugandha, Gunter, Jennifer H, Burgess, Joshua T, Adams, Mark N, O'Byrne, Kenneth, Thompson, Erik W, Duijf, Pascal HG
Publicado 2023

The Therapeutic Potential of DNA Damage Repair Pathways and Genomic Stability in Lung Cancer

por Burgess, Joshua T., Rose, Maddison, Boucher, Didier, Plowman, Jennifer, Molloy, Christopher, Fisher, Mark, O'Leary, Connor, Richard, Derek J., O'Byrne, Kenneth J., Bolderson, Emma
Publicado 2020

Activation and cleavage of SASH1 by caspase-3 mediates an apoptotic response

por Burgess, Joshua T, Bolderson, Emma, Adams, Mark N, Baird, Anne-Marie, Zhang, Shu-Dong, Gately, Kathy A, Umezawa, Kazuo, O'Byrne, Kenneth J, Richard, Derek J
Publicado 2016

SASH1 is a prognostic indicator and potential therapeutic target in non-small cell lung cancer

por Burgess, Joshua T., Bolderson, Emma, Adams, Mark N., Duijf, Pascal H. G., Zhang, Shu-Dong, Gray, Steven G., Wright, Gavin, Richard, Derek J., O’Byrne, Kenneth J.
Publicado 2020

The fructose-bisphosphate, Aldolase A (ALDOA), facilitates DNA-PKcs and ATM kinase activity to regulate DNA double-strand break repair

por Sobanski, Thais, Suraweera, Amila, Burgess, Joshua T., Richard, Iain, Cheong, Chee Man, Dave, Keyur, Rose, Maddison, Adams, Mark N., O’Byrne, Kenneth J., Richard, Derek J., Bolderson, Emma
Publicado 2023

The Impact of Rare Human Variants on Barrier-To-Auto-Integration Factor 1 (Banf1) Structure and Function

por Rose, Maddison, Bai, Bond, Tang, Ming, Cheong, Chee Man, Beard, Sam, Burgess, Joshua T., Adams, Mark N., O’Byrne, Kenneth J., Richard, Derek J., Gandhi, Neha S., Bolderson, Emma
Publicado 2021

hSSB1 (NABP2/ OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway

por Paquet, Nicolas, Adams, Mark N., Leong, Vincent, Ashton, Nicholas W., Touma, Christine, Gamsjaeger, Roland, Cubeddu, Liza, Beard, Sam, Burgess, Joshua T., Bolderson, Emma, O'Byrne, Ken J., Richard, Derek J.
Publicado 2015

SASH1 mediates sensitivity of breast cancer cells to chloropyramine and is associated with prognosis in breast cancer

por Burgess, Joshua T., Bolderson, Emma, Saunus, Jodi M., Zhang, Shu-Dong, Reid, Lynne E., McNicol, Anne Marie, Lakhani, Sunil R., Cuff, Katharine, Richard, Kerry, Richard, Derek J., O'Byrne, Kenneth J.
Publicado 2016

Barrier-to-autointegration-factor (Banf1) modulates DNA double-strand break repair pathway choice via regulation of DNA-dependent kinase (DNA-PK) activity

por Burgess, Joshua T, Cheong, Chee Man, Suraweera, Amila, Sobanski, Thais, Beard, Sam, Dave, Keyur, Rose, Maddison, Boucher, Didier, Croft, Laura V, Adams, Mark N, O’Byrne, Kenneth, Richard, Derek J, Bolderson, Emma
Publicado 2021

COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks

por Suraweera, Amila, Gandhi, Neha S., Beard, Sam, Burgess, Joshua T., Croft, Laura V., Bolderson, Emma, Naqi, Ali, Ashton, Nicholas W., Adams, Mark N., Savage, Kienan I., Zhang, Shu-Dong, O’Byrne, Kenneth J., Richard, Derek J.
Publicado 2021

hSSB2 (NABP1) is required for the recruitment of RPA during the cellular response to DNA UV damage

por Boucher, Didier, Kariawasam, Ruvini, Burgess, Joshua, Gimenez, Adrian, Ocampo, Tristan E., Ferguson, Blake, Naqi, Ali, Walker, Graeme J., Bolderson, Emma, Gamsjaeger, Roland, O’Byrne, Kenneth J., Cubeddu, Liza, Khanna, Kum Kum, Richard, Derek J.
Publicado 2021

Elevating CDCA3 levels in non-small cell lung cancer enhances sensitivity to platinum-based chemotherapy

por Kildey, Katrina, Gandhi, Neha S., Sahin, Katherine B., Shah, Esha T., Boittier, Eric, Duijf, Pascal H. G., Molloy, Christopher, Burgess, Joshua T., Beard, Sam, Bolderson, Emma, Suraweera, Amila, Richard, Derek J., O’Byrne, Kenneth J., Adams, Mark N.
Publicado 2021

Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage

por Bolderson, Emma, Burgess, Joshua T., Li, Jun, Gandhi, Neha S., Boucher, Didier, Croft, Laura V., Beard, Samuel, Plowman, Jennifer J., Suraweera, Amila, Adams, Mark N., Naqi, Ali, Zhang, Shu-Dong, Sinclair, David A., O’Byrne, Kenneth J., Richard, Derek J.
Publicado 2019

Bead-linked transposomes enable a normalization-free workflow for NGS library preparation

por Bruinsma, Stephen, Burgess, Joshua, Schlingman, Daniel, Czyz, Agata, Morrell, Natalie, Ballenger, Catherine, Meinholz, Heather, Brady, Lee, Khanna, Anupama, Freeberg, Lindsay, Jackson, Rosamond G, Mathonet, Pascale, Verity, Susan C, Slatter, Andrew F, Golshani, Rooz, Grunenwald, Haiying, Schroth, Gary P, Gormley, Niall A
Publicado 2018