A tumor suppressor function of Smurf2 associated with controlling chromatin landscape and genome stability through RNF20

por Blank, Michael, Tang, Yi, Yamashita, Motozo, Burkett, Sandra S., Cheng, Steven Y., Zhang, Ying E.
Publicado 2012

Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenance

por Singh, Satyendra K., Williams, Carrie A., Klarmann, Kimberly, Burkett, Sandra S., Keller, Jonathan R., Oberdoerffer, Philipp
Publicado 2013

Chronic Exposure to Nitric Oxide Induces P53 Mutations and Malignant-like Features in Human Breast Epithelial Cells

por Cheng, Robert Y. S., Burkett, Sandra, Ambs, Stefan, Moody, Terry, Wink, David A., Ridnour, Lisa A.
Publicado 2023

Chromosome painting in the manatee supports Afrotheria and Paenungulata

por Kellogg, Margaret E, Burkett, Sandra, Dennis, Thomas R, Stone, Gary, Gray, Brian A, McGuire, Peter M, Zori, Roberto T, Stanyon, Roscoe
Publicado 2007

Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2

por Hartford, Suzanne A., Chittela, Rajanikant, Ding, Xia, Vyas, Aradhana, Martin, Betty, Burkett, Sandra, Haines, Diana C., Southon, Eileen, Tessarollo, Lino, Sharan, Shyam K.
Publicado 2016

BRE/BRCC45 regulates CDC25A stability by recruiting USP7 in response to DNA damage

por Biswas, Kajal, Philip, Subha, Yadav, Aditya, Martin, Betty K., Burkett, Sandra, Singh, Vaibhav, Babbar, Anav, North, Susan Lynn, Chang, Suhwan, Sharan, Shyam K.
Publicado 2018

TYMS promotes genomic instability and tumor progression in Ink4a/Arf null background

por Guijarro, Maria V., Nawab, Akbar, Dib, Peter, Burkett, Sandra, Luo, Xiaoping, Feely, Michael, Nasri, Elham, Seifert, Robert P., Kaye, Frederic J., Zajac-Kaye, Maria
Publicado 2023

The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation

por Xu, Xiaoping, Ni, Kai, He, Yafeng, Ren, Jianke, Sun, Chongkui, Liu, Yie, Aladjem, Mirit I., Burkett, Sandra, Finney, Richard, Ding, Xia, Sharan, Shyam K., Muegge, Kathrin
Publicado 2021

Rilotumumab Resistance Acquired by Intracrine Hepatocyte Growth Factor Signaling

por Cecchi, Fabiola, Rex, Karen, Schmidt, Joanna, Vocke, Cathy D., Lee, Young H., Burkett, Sandra, Baker, Daniel, Damore, Michael A., Coxon, Angela, Burgess, Teresa L., Bottaro, Donald P.
Publicado 2023

Development and Preclinical Application of an Immunocompetent Transplant Model of Basal Breast Cancer with Lung, Liver and Brain Metastases

por Aprelikova, Olga, Tomlinson, Christine C., Hoenerhoff, Mark, Hixon, Julie A., Durum, Scott K., Qiu, Ting-hu, He, Siping, Burkett, Sandra, Liu, Zi-Yao, Swanson, Steven M., Green, Jeffrey E.
Publicado 2016

Mesothelioma patient derived tumor xenografts with defined BAP1 mutations that mimic the molecular characteristics of human malignant mesothelioma

por Kalra, Neetu, Zhang, Jingli, Thomas, Anish, Xi, Liqiang, Cheung, Mitchell, Talarchek, Jacqueline, Burkett, Sandra, Tsokos, Maria G, Chen, Yuanbin, Raffeld, Mark, Miettinen, Markku, Pastan, Ira, Testa, Joseph R, Hassan, Raffit
Publicado 2015

Whole Genome Sequencing of Newly Established Pancreatic Cancer Lines Identifies Novel Somatic Mutation (c.2587G>A) in Axon Guidance Receptor Plexin A1 as Enhancer of Proliferation...

por Sorber, Rebecca, Teper, Yaroslav, Abisoye-Ogunniyan, Abisola, Waterfall, Joshua J., Davis, Sean, Killian, J. Keith, Pineda, Marbin, Ray, Satyajit, McCord, Matt R., Pflicke, Holger, Burkett, Sandra Sczerba, Meltzer, Paul S., Rudloff, Udo
Publicado 2016

RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females

por Kuznetsov, Sergey, Pellegrini, Manuela, Shuda, Kristy, Fernandez-Capetillo, Oscar, Liu, Yilun, Martin, Betty K., Burkett, Sandra, Southon, Eileen, Pati, Debananda, Tessarollo, Lino, West, Stephen C., Donovan, Peter J., Nussenzweig, Andre, Sharan, Shyam K.
Publicado 2007

Characterization of the metastatic phenotype of a panel of established osteosarcoma cells

por Ren, Ling, Mendoza, Arnulfo, Zhu, Jack, Briggs, Joseph W., Halsey, Charles, Hong, Ellen S., Burkett, Sandra S., Morrow, James J., Lizardo, Michael M., Osborne, Tanasa, Li, Samuel Q., Luu, Hue H., Meltzer, Paul, Khanna, Chand
Publicado 2015

EML4-ALK induces cellular senescence in mortal normal human cells and promotes anchorage-independent growth in hTERT-transduced normal human cells

por Miyanaga, Akihiko, Matsumoto, Masaru, Beck, Jessica A., Horikawa, Izumi, Oike, Takahiro, Okayama, Hirokazu, Tanaka, Hiromi, Burkett, Sandra S., Robles, Ana I., Khan, Mohammed, Lissa, Delphine, Seike, Masahiro, Gemma, Akihiko, Mano, Hiroyuki, Harris, Curtis C.
Publicado 2021

Loss of Brca1 and Trp53 in adult mouse mammary ductal epithelium results in development of hormone receptor-positive or hormone receptor-negative tumors, depending on inactivation...

por Szabova, Ludmila, Gordon, Melanie B., Lu, Lucy, Pate, Nathan, Bassel, Laura, Iacovelli, Anthony J., Karim, Baktiar, Homan, Philip J., Householder, Deborah B., Guerin, Theresa M., Burkett, Sandra, Day, Amanda M., Custer, Wendi, Weaver Ohler, Zoe
Publicado 2022

Saturation genome editing of 11 codons and exon 13 of BRCA2 coupled with chemotherapeutic drug response accurately determines pathogenicity of variants

por Sahu, Sounak, Sullivan, Teresa L., Mitrophanov, Alexander Y., Galloux, Mélissa, Nousome, Darryl, Southon, Eileen, Caylor, Dylan, Mishra, Arun Prakash, Evans, Christine N., Clapp, Michelle E., Burkett, Sandra, Malys, Tyler, Chari, Raj, Biswas, Kajal, Sharan, Shyam K.
Publicado 2023

Mesothelioma Mouse Models with Mixed Genomic States of Chromosome and Microsatellite Instability

por Song, Yurong, Baxter, Shaneen S., Dai, Lisheng, Sanders, Chelsea, Burkett, Sandra, Baugher, Ryan N., Mellott, Stephanie D., Young, Todd B., Lawhorn, Heidi E., Difilippantonio, Simone, Karim, Baktiar, Kadariya, Yuwaraj, Pinto, Ligia A., Testa, Joseph R., Shoemaker, Robert H.
Publicado 2022

Thymidylate synthase accelerates Men1-mediated pancreatic tumor progression and reduces survival

por Vijayakurup, Vinod, Maeng, Kyungah, Lee, Hye Seung, Meyer, Benjamin, Burkett, Sandra, Nawab, Akbar, Dougherty, Michael W., Jobin, Christian, Mahmud, Iqbal, Garrett, Timothy J., Feely, Michael, Lee, Kyoung Bun, Kaye, Frederic J., Guijarro, Maria V., Zajac-Kaye, Maria
Publicado 2022

Characterization of BRCA2 R3052Q variant in mice supports its functional impact as a low-risk variant

por Mishra, Arun Prakash, Hartford, Suzanne, Chittela, Rajani Kant, Sahu, Sounak, Kharat, Suhas S., Alvaro-Aranda, Lucia, Contreras-Perez, Aida, Sullivan, Teresa, Martin, Betty K., Albaugh, Mary, Southon, Eileen, Burkett, Sandra, Karim, Baktiar, Carreira, Aura, Tessarollo, Lino, Sharan, Shyam K.
Publicado 2023