An Overview of in vitro Methods to Study Microglia

por Timmerman, Raissa, Burm, Saskia M., Bajramovic, Jeffrey J.
Publicado 2018

VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases

por Borggrewe, Malte, Grit, Corien, Den Dunnen, Wilfred F. A., Burm, Saskia M., Bajramovic, Jeffrey J., Noelle, Randolph J., Eggen, Bart J. L., Laman, Jon D.
Publicado 2018

Transcriptome and proteome profiling of neural stem cells from the human subventricular zone in Parkinson’s disease

por Donega, Vanessa, Burm, Saskia M., van Strien, Miriam E., van Bodegraven, Emma J., Paliukhovich, Iryna, Geut, Hanneke, van de Berg, Wilma D. J., Li, Ka Wan, Smit, August B., Basak, Onur, Hol, Elly M.
Publicado 2019

Transcriptional profiling of macaque microglia reveals an evolutionary preserved gene expression program

por Dubbelaar, M.L., Misrielal, C., Bajramovic, J.J., Burm, S.M., Zuiderwijk-Sick, E.A., Brouwer, N., Grit, C., Kooistra, S.M., Shinjo, S.M.O., Marie, S.K.N., Boddeke, H.W.G.M., Eggen, B.J.L.
Publicado 2021

Mechanistic and pharmacodynamic studies of DuoBody-CD3x5T4 in preclinical tumor models

por Kemper, Kristel, Gielen, Ellis, Boross, Peter, Houtkamp, Mischa, Plantinga, Theo S, de Poot, Stefanie AH, Burm, Saskia M, Janmaat, Maarten L, Koopman, Louise A, van den Brink, Edward N, Rademaker, Rik, Verzijl, Dennis, Engelberts, Patrick J, Satijn, David, Sasser, A Kate, Breij, Esther CW
Publicado 2022

Systematic study of tissue factor expression in solid tumors

por de Bono, Johann S., Harris, Jeffrey R., Burm, Saskia M., Vanderstichele, Adriaan, Houtkamp, Mischa A., Aarass, Saida, Riisnaes, Ruth, Figueiredo, Ines, Nava Rodrigues, Daniel, Christova, Rossitza, Olbrecht, Siel, Niessen, Hans W. M., Ruuls, Sigrid R., Schuurhuis, Danita H., Lammerts van Bueren, Jeroen J., Breij, Esther C. W., Vergote, Ignace
Publicado 2022

An Fc-inert PD-L1×4-1BB bispecific antibody mediates potent anti-tumor immunity in mice by combining checkpoint inhibition and conditional 4-1BB co-stimulation

por Muik, Alexander, Altintas, Isil, Gieseke, Friederike, Schoedel, Kristina B, Burm, Saskia M, Toker, Aras, Salcedo, Theodora W., Verzijl, Dennis, Eisel, David, Grunwitz, Christian, Kranz, Lena M, Vormehr, Mathias, Satijn, David P.E., Diken, Mustafa, Kreiter, Sebastian, Sasser, Kate, Ahmadi, Tahamtan, Türeci, Özlem, Breij, Esther C.W., Jure-Kunkel, Maria, Sahin, Ugur
Publicado 2022

DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity

por Muik, Alexander, Adams, Homer C, Gieseke, Friederike, Altintas, Isil, Schoedel, Kristina B, Blum, Jordan M, Sänger, Bianca, Burm, Saskia M, Stanganello, Eliana, Verzijl, Dennis, Spires, Vanessa M, Vascotto, Fulvia, Toker, Aras, Quinkhardt, Juliane, Fereshteh, Mark, Diken, Mustafa, Satijn, David P E, Kreiter, Sebastian, Ahmadi, Tahamtan, Breij, Esther C W, Türeci, Özlem, Sasser, Kate, Sahin, Ugur, Jure-Kunkel, Maria
Publicado 2022

Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors

por Muik, Alexander, Garralda, Elena, Altintas, Isil, Gieseke, Friederike, Geva, Ravit, Ben-Ami, Eytan, Maurice-Dror, Corinne, Calvo, Emiliano, LoRusso, Patricia M., Alonso, Guzman, Rodriguez-Ruiz, Maria E., Schoedel, Kristina B., Blum, Jordan M., Sänger, Bianca, Salcedo, Theodora W., Burm, Saskia M., Stanganello, Eliana, Verzijl, Dennis, Vascotto, Fulvia, Sette, Angelica, Quinkhardt, Juliane, Plantinga, Theo S., Toker, Aras, van den Brink, Edward N., Fereshteh, Mark, Diken, Mustafa, Satijn, David, Kreiter, Sebastian, Breij, Esther C.W., Bajaj, Gaurav, Lagkadinou, Eleni, Sasser, Kate, Türeci, Özlem, Forssmann, Ulf, Ahmadi, Tahamtan, Şahin, Uğur, Jure-Kunkel, Maria, Melero, Ignacio
Publicado 2022