Mass photometry reveals SARS-CoV-2 spike stabilisation to impede ACE2 binding through altered conformational dynamics

por Burnap, Sean A., Struwe, Weston B.
Publicado 2022

Endothelial cells exposed to atheroprotective flow secrete follistatin-like 1 protein which reduces transcytosis and inflammation

por Ghim, Mean, Pang, Kuin T., Burnap, Sean A., Baig, Ferheen, Yin, Xiaoke, Arshad, Mehwish, Mayr, Manuel, Weinberg, Peter D.
Publicado 2021

A Proteomics-Based Assessment of Inflammation Signatures in Endotoxemia

por Burnap, Sean A., Mayr, Ursula, Shankar-Hari, Manu, Cuello, Friederike, Thomas, Mark R., Shah, Ajay M., Sabroe, Ian, Storey, Robert F., Mayr, Manuel
Publicado 2021

Uncovering the Role of N-Glycan Occupancy on the Cooperative Assembly of Spike and Angiotensin Converting Enzyme 2 Complexes: Insights from Glycoengineering and Native Mass Spectro...

por El-Baba, Tarick J., Lutomski, Corinne A., Burnap, Sean A., Bolla, Jani R., Baker, Lindsay A., Baldwin, Andrew J., Struwe, Weston B., Robinson, Carol V.
Publicado 2023

Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein

por Burnap, Sean A., Ortega-Prieto, Ana Maria, Jimenez-Guardeño, Jose M., Ali, Hashim, Takov, Kaloyan, Fish, Matthew, Shankar-Hari, Manu, Giacca, Mauro, Malim, Michael H., Mayr, Manuel
Publicado 2023

Reduced secretion of neuronal growth regulator 1 contributes to impaired adipose-neuronal crosstalk in obesity

por Duregotti, Elisa, Reumiller, Christina M., Mayr, Ursula, Hasman, Maria, Schmidt, Lukas E., Burnap, Sean A., Theofilatos, Konstantinos, Barallobre-Barreiro, Javier, Beran, Arne, Grandoch, Maria, Viviano, Alessandro, Jahangiri, Marjan, Mayr, Manuel
Publicado 2022

Neutrophil-Derived Protein S100A8/A9 Alters the Platelet Proteome in Acute Myocardial Infarction and Is Associated With Changes in Platelet Reactivity

por Joshi, Abhishek, Schmidt, Lukas E., Burnap, Sean A., Lu, Ruifang, Chan, Melissa V., Armstrong, Paul C., Baig, Ferheen, Gutmann, Clemens, Willeit, Peter, Santer, Peter, Barwari, Temo, Theofilatos, Konstantinos, Kiechl, Stefan, Willeit, Johann, Warner, Timothy D., Mathur, Anthony, Mayr, Manuel
Publicado 2021

PCSK9 Activity Is Potentiated Through HDL Binding

por Burnap, Sean A., Sattler, Katherine, Pechlaner, Raimund, Duregotti, Elisa, Lu, Ruifang, Theofilatos, Konstantinos, Takov, Kaloyan, Heusch, Gerd, Tsimikas, Sotirios, Fernández-Hernando, Carlos, Berry, Sarah E., Hall, Wendy L., Notdurfter, Marlene, Rungger, Gregorio, Paulweber, Bernhard, Willeit, Johann, Kiechl, Stefan, Levkau, Bodo, Mayr, Manuel
Publicado 2021

Association of cardiometabolic microRNAs with COVID-19 severity and mortality

por Gutmann, Clemens, Khamina, Kseniya, Theofilatos, Konstantinos, Diendorfer, Andreas B, Burnap, Sean A, Nabeebaccus, Adam, Fish, Matthew, McPhail, Mark J W, O'Gallagher, Kevin, Schmidt, Lukas E, Cassel, Christian, Auzinger, Georg, Napoli, Salvatore, Mujib, Salma F, Trovato, Francesca, Sanderson, Barnaby, Merrick, Blair, Roy, Roman, Edgeworth, Jonathan D, Shah, Ajay M, Hayday, Adrian C, Traby, Ludwig, Hackl, Matthias, Eichinger, Sabine, Shankar-Hari, Manu, Mayr, Manuel
Publicado 2021

SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care

por Gutmann, Clemens, Takov, Kaloyan, Burnap, Sean A., Singh, Bhawana, Ali, Hashim, Theofilatos, Konstantinos, Reed, Ella, Hasman, Maria, Nabeebaccus, Adam, Fish, Matthew, McPhail, Mark JW., O’Gallagher, Kevin, Schmidt, Lukas E., Cassel, Christian, Rienks, Marieke, Yin, Xiaoke, Auzinger, Georg, Napoli, Salvatore, Mujib, Salma F., Trovato, Francesca, Sanderson, Barnaby, Merrick, Blair, Niazi, Umar, Saqi, Mansoor, Dimitrakopoulou, Konstantina, Fernández-Leiro, Rafael, Braun, Silke, Kronstein-Wiedemann, Romy, Doores, Katie J., Edgeworth, Jonathan D., Shah, Ajay M., Bornstein, Stefan R., Tonn, Torsten, Hayday, Adrian C., Giacca, Mauro, Shankar-Hari, Manu, Mayr, Manuel
Publicado 2021