A modified gene trap approach for improved high-throughput cancer drug discovery

por Morris, Shelli M., Mhyre, Andrew J., Carmack, Savanna S., Myers, Carrie H., Burns, Connor, Ye, Wenjuan, Ferrer, Marc, Olson, James M., Klinghoffer, Richard A.
Publicado 2018

Voruciclib, a clinical stage oral CDK9 inhibitor, represses MCL-1 and sensitizes high-risk Diffuse Large B-cell Lymphoma to BCL2 inhibition

por Dey, Joyoti, Deckwerth, Thomas L., Kerwin, William S., Casalini, Joseph R., Merrell, Angela J., Grenley, Marc O., Burns, Connor, Ditzler, Sally H., Dixon, Chantel P., Beirne, Emily, Gillespie, Kate C., Kleinman, Edward F., Klinghoffer, Richard A.
Publicado 2017

Trackable Intratumor Microdosing and Spatial Profiling Provide Early Insights into Activity of Investigational Agents in the Intact Tumor Microenvironment

por Derry, Jonathan M.J., Burns, Connor, Frazier, Jason P., Beirne, Emily, Grenley, Marc, DuFort, Christopher C., Killingbeck, Emily, Leon, Michael, Williams, Claire, Gregory, Mark, Houlton, Jeffrey, Clayburgh, Daniel, Swiecicki, Paul, Huszar, Dennis, Berger, Allison, Klinghoffer, Richard A.
Publicado 2023