Non-Alcoholic Fatty Liver Disease and Vitamin D in the UK Biobank: A Two-Sample Bidirectional Mendelian Randomisation Study

por Zhang, Zixuan, Burrows, Kimberley, Fuller, Harriett, Speliotes, Elizabeth K., Abeysekera, Kushala W. M., Thorne, James L., Lewis, Sarah J., Zulyniak, Michael A., Moore, J. Bernadette
Publicado 2023

Epigenome-wide association study of asthma and wheeze in childhood and adolescence

por Arathimos, Ryan, Suderman, Matthew, Sharp, Gemma C., Burrows, Kimberley, Granell, Raquel, Tilling, Kate, Gaunt, Tom R., Henderson, John, Ring, Susan, Richmond, Rebecca C., Relton, Caroline L.
Publicado 2017

Cardiometabolic phenotypes and mitochondrial DNA copy number in two cohorts of UK women

por Guyatt, Anna L., Burrows, Kimberley, Guthrie, Philip A.I., Ring, Sue, McArdle, Wendy, Day, Ian N.M., Ascione, Raimondo, Lawlor, Debbie A., Gaunt, Tom R., Rodriguez, Santiago
Publicado 2018

Characterisation of ethnic differences in DNA methylation between UK-resident South Asians and Europeans

por Elliott, Hannah R., Burrows, Kimberley, Min, Josine L., Tillin, Therese, Mason, Dan, Wright, John, Santorelli, Gillian, Davey Smith, George, Lawlor, Deborah A., Hughes, Alun D., Chaturvedi, Nishi, Relton, Caroline L.
Publicado 2022

Association of germline TYK2 variation with lung cancer and non‐Hodgkin lymphoma risk

por Yarmolinsky, James, Amos, Christopher I., Hung, Rayjean J., Moreno, Victor, Burrows, Kimberley, Smith‐Byrne, Karl, Atkins, Joshua R., Brennan, Paul, McKay, James D., Martin, Richard M., Davey Smith, George
Publicado 2022

A genome-wide association study of mitochondrial DNA copy number in two population-based cohorts

por Guyatt, Anna L., Brennan, Rebecca R., Burrows, Kimberley, Guthrie, Philip A. I., Ascione, Raimondo, Ring, Susan M., Gaunt, Tom R., Pyle, Angela, Cordell, Heather J., Lawlor, Debbie A., Chinnery, Patrick F., Hudson, Gavin, Rodriguez, Santiago
Publicado 2019

Smoking, DNA Methylation, and Lung Function: a Mendelian Randomization Analysis to Investigate Causal Pathways

por Jamieson, Emily, Korologou-Linden, Roxanna, Wootton, Robyn E., Guyatt, Anna L., Battram, Thomas, Burrows, Kimberley, Gaunt, Tom R., Tobin, Martin D., Munafò, Marcus, Davey Smith, George, Tilling, Kate, Relton, Caroline, Richardson, Tom G., Richmond, Rebecca C.
Publicado 2020

Epigenome-wide association study of asthma and wheeze characterizes loci within HK1

por Everson, Todd M., Zhang, Hongmei, Lockett, Gabrielle A., Kaushal, Akhilesh, Forthofer, Melinda, Ewart, Susan L., Burrows, Kimberley, Relton, Caroline L., Sharp, Gemma C., Henderson, A. John, Patil, Veeresh K., Rezwan, Faisal I., Arshad, S. Hasan, Holloway, John W., Karmaus, Wilfried
Publicado 2019

Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study

por Morales Berstein, Fernanda, McCartney, Daniel L, Lu, Ake T, Tsilidis, Konstantinos K, Bouras, Emmanouil, Haycock, Philip, Burrows, Kimberley, Phipps, Amanda I, Buchanan, Daniel D, Cheng, Iona, Martin, Richard M, Davey Smith, George, Relton, Caroline L, Horvath, Steve, Marioni, Riccardo E, Richardson, Tom G, Richmond, Rebecca C
Publicado 2022

Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: A Mendelian randomization study

por Gormley, Mark, Yarmolinsky, James, Dudding, Tom, Burrows, Kimberley, Martin, Richard M., Thomas, Steven, Tyrrell, Jessica, Brennan, Paul, Pring, Miranda, Boccia, Stefania, Olshan, Andrew F., Diergaarde, Brenda, Hung, Rayjean J., Liu, Geoffrey, Legge, Danny, Tajara, Eloiza H., Severino, Patricia, Lacko, Martin, Ness, Andrew R., Davey Smith, George, Vincent, Emma E., Richmond, Rebecca C.
Publicado 2021

Genetically proxied glucose-lowering drug target perturbation and risk of cancer: a Mendelian randomisation analysis

por Yarmolinsky, James, Bouras, Emmanouil, Constantinescu, Andrei, Burrows, Kimberley, Bull, Caroline J., Vincent, Emma E., Martin, Richard M., Dimopoulou, Olympia, Lewis, Sarah J., Moreno, Victor, Vujkovic, Marijana, Chang, Kyong-Mi, Voight, Benjamin F., Tsao, Philip S., Gunter, Marc J., Hampe, Jochen, Pellatt, Andrew J., Pharoah, Paul D. P., Schoen, Robert E., Gallinger, Steven, Jenkins, Mark A., Pai, Rish K., Gill, Dipender, Tsilidis, Kostas K.
Publicado 2023

Maternal alcohol consumption and offspring DNA methylation: findings from six general population-based birth cohorts

por Sharp, Gemma C, Arathimos, Ryan, Reese, Sarah E, Page, Christian M, Felix, Janine, Küpers, Leanne K, Rifas-Shiman, Sheryl L, Liu, Chunyu, Burrows, Kimberley, Zhao, Shanshan, Magnus, Maria C, Duijts, Liesbeth, Corpeleijn, Eva, DeMeo, Dawn L, Litonjua, Augusto, Baccarelli, Andrea, Hivert, Marie-France, Oken, Emily, Snieder, Harold, Jaddoe, Vincent, Nystad, Wenche, London, Stephanie J, Relton, Caroline L, Zuccolo, Luisa
Publicado 2018

Investigating the effect of sexual behaviour on oropharyngeal cancer risk: a methodological assessment of Mendelian randomization

por Gormley, Mark, Dudding, Tom, Kachuri, Linda, Burrows, Kimberley, Chong, Amanda H. W., Martin, Richard M., Thomas, Steven J., Tyrrell, Jessica, Ness, Andrew R., Brennan, Paul, Munafò, Marcus R., Pring, Miranda, Boccia, Stefania, Olshan, Andrew F., Diergaarde, Brenda, Hung, Rayjean J., Liu, Geoffrey, Tajara, Eloiza H., Severino, Patricia, Toporcov, Tatiana N., Lacko, Martin, Waterboer, Tim, Brenner, Nicole, Smith, George Davey, Vincent, Emma E., Richmond, Rebecca C.
Publicado 2022

Design and quality control of large-scale two-sample Mendelian randomization studies

por Haycock, Philip C, Borges, Maria Carolina, Burrows, Kimberley, Lemaitre, Rozenn N, Harrison, Sean, Burgess, Stephen, Chang, Xuling, Westra, Jason, Khankari, Nikhil K, Tsilidis, Kostas K, Gaunt, Tom, Hemani, Gibran, Zheng, Jie, Truong, Therese, O’Mara, Tracy A, Spurdle, Amanda B, Law, Matthew H, Slager, Susan L, Birmann, Brenda M, Saberi Hosnijeh, Fatemeh, Mariosa, Daniela, Amos, Christopher I, Hung, Rayjean J, Zheng, Wei, Gunter, Marc J, Davey Smith, George, Relton, Caroline, Martin, Richard M
Publicado 2023

The association between genetically elevated polyunsaturated fatty acids and risk of cancer

por Haycock, Philip C., Borges, Maria Carolina, Burrows, Kimberley, Lemaitre, Rozenn N., Burgess, Stephen, Khankari, Nikhil K., Tsilidis, Konstantinos K., Gaunt, Tom R., Hemani, Gibran, Zheng, Jie, Truong, Therese, Birmann, Brenda M., OMara, Tracy, Spurdle, Amanda B., Iles, Mark M., Law, Matthew H., Slager, Susan L., Saberi Hosnijeh, Fatemeh, Mariosa, Daniela, Cotterchio, Michelle, Cerhan, James R., Peters, Ulrike, Enroth, Stefan, Gharahkhani, Puya, Le Marchand, Loic, Williams, Ann C., Block, Robert C., Amos, Christopher I., Hung, Rayjean J., Zheng, Wei, Gunter, Marc J., Smith, George Davey, Relton, Caroline, Martin, Richard M.
Publicado 2023

Association between circulating inflammatory markers and adult cancer risk: a Mendelian randomization analysis

por Yarmolinsky, James, Robinson, Jamie W, Mariosa, Daniela, Karhunen, Ville, Huang, Jian, Dimou, Niki, Murphy, Neil, Burrows, Kimberley, Bouras, Emmanouil, Smith-Byrne, Karl, Lewis, Sarah J, Galesloot, Tessel E, Kiemeney, Lambertus A, Vermeulen, Sita, Martin, Paul, Albanes, Demetrius, Hou, Lifang, Newcomb, Polly A, White, Emily, Wolk, Alicja, Wu, Anna H, Marchand, Loïc Le, Phipps, Amanda I, Buchanan, Daniel D, Zhao, Sizheng Steven, Gill, Dipender, Chanock, Stephen J, Purdue, Mark P, Smith, George Davey, Brennan, Paul, Herzig, Karl-Heinz, Jarvelin, Marjo-Riitta, Dehghan, Abbas, Johansson, Mattias, Gunter, Marc J, Tsilidis, Kostas K, Martin, Richard M
Publicado 2023

Applying Mendelian randomization to appraise causality in relationships between nutrition and cancer

por Wade, Kaitlin H., Yarmolinsky, James, Giovannucci, Edward, Lewis, Sarah J., Millwood, Iona Y., Munafò, Marcus R., Meddens, Fleur, Burrows, Kimberley, Bell, Joshua A., Davies, Neil M., Mariosa, Daniela, Kanerva, Noora, Vincent, Emma E., Smith-Byrne, Karl, Guida, Florence, Gunter, Marc J., Sanderson, Eleanor, Dudbridge, Frank, Burgess, Stephen, Cornelis, Marilyn C., Richardson, Tom G., Borges, Maria Carolina, Bowden, Jack, Hemani, Gibran, Cho, Yoonsu, Spiller, Wes, Richmond, Rebecca C., Carter, Alice R., Langdon, Ryan, Lawlor, Deborah A., Walters, Robin G., Vimaleswaran, Karani Santhanakrishnan, Anderson, Annie, Sandu, Meda R., Tilling, Kate, Davey Smith, George, Martin, Richard M., Relton, Caroline L.
Publicado 2022

Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns: Findings From the Pregnancy and Childhood Epigenetics Consortium

por Kazmi, Nabila, Sharp, Gemma C., Reese, Sarah E., Vehmeijer, Florianne O., Lahti, Jari, Page, Christian M., Zhang, Weiming, Rifas-Shiman, Sheryl L., Rezwan, Faisal I., Simpkin, Andrew J., Burrows, Kimberley, Richardson, Tom G., Santos Ferreira, Diana L., Fraser, Abigail, Harmon, Quaker E., Zhao, Shanshan, Jaddoe, Vincent W.V., Czamara, Darina, Binder, Elisabeth B., Magnus, Maria C., Håberg, Siri E., Nystad, Wenche, Nohr, Ellen A., Starling, Anne P., Kechris, Katerina J., Yang, Ivana V., DeMeo, Dawn L., Litonjua, Augusto A., Baccarelli, Andrea, Oken, Emily, Holloway, John W., Karmaus, Wilfried, Arshad, Syed H., Dabelea, Dana, Sørensen, Thorkild I.A., Laivuori, Hannele, Raikkonen, Katri, Felix, Janine F., London, Stephanie J., Hivert, Marie-France, Gaunt, Tom R., Lawlor, Debbie A., Relton, Caroline L.
Publicado 2019

Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology

por Ferreira, Manuel A, Vonk, Judith M, Baurecht, Hansjörg, Marenholz, Ingo, Tian, Chao, Hoffman, Joshua D, Helmer, Quinta, Tillander, Annika, Ullemar, Vilhelmina, van Dongen, Jenny, Lu, Yi, Rüschendorf, Franz, Esparza-Gordillo, Jorge, Medway, Chris W, Mountjoy, Edward, Burrows, Kimberley, Hummel, Oliver, Grosche, Sarah, Brumpton, Ben M, Witte, John S, Hottenga, Jouke-Jan, Willemsen, Gonneke, Zheng, Jie, Rodríguez, Elke, Hotze, Melanie, Franke, Andre, Revez, Joana A, Beesley, Jonathan, Matheson, Melanie C, Dharmage, Shyamali C, Bain, Lisa M, Fritsche, Lars G, Gabrielsen, Maiken E, Balliu, Brunilda, Nielsen, Jonas B, Zhou, Wei, Hveem, Kristian, Langhammer, Arnulf, Holmen, Oddgeir L, Løset, Mari, Abecasis, Gonçalo R, Willer, Cristen J, Arnold, Andreas, Homuth, Georg, Schmidt, Carsten O, Thompson, Philip J, Martin, Nicholas G, Duffy, David L, Novak, Natalija, Schulz, Holger, Karrasch, Stefan, Gieger, Christian, Strauch, Konstantin, Melles, Ronald B, Hinds, David A, Hübner, Norbert, Weidinger, Stephan, Magnusson, Patrik KE, Jansen, Rick, Jorgenson, Eric, Lee, Young-Ae, Boomsma, Dorret I, Almqvist, Catarina, Karlsson, Robert, Koppelman, Gerard H, Paternoster, Lavinia
Publicado 2017

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

por Min, Josine L, Hemani, Gibran, Hannon, Eilis, Dekkers, Koen F, Castillo-Fernandez, Juan, Luijk, René, Carnero-Montoro, Elena, Lawson, Daniel J, Burrows, Kimberley, Suderman, Matthew, Bretherick, Andrew D, Richardson, Tom G, Klughammer, Johanna, Iotchkova, Valentina, Sharp, Gemma, Al Khleifat, Ahmad, Shatunov, Aleksey, Iacoangeli, Alfredo, McArdle, Wendy L, Ho, Karen M, Kumar, Ashish, Söderhäll, Cilla, Soriano-Tárraga, Carolina, Giralt-Steinhauer, Eva, Kazmi, Nabila, Mason, Dan, McRae, Allan F, Corcoran, David L, Sugden, Karen, Kasela, Silva, Cardona, Alexia, Day, Felix R, Cugliari, Giovanni, Viberti, Clara, Guarrera, Simonetta, Lerro, Michael, Gupta, Richa, Bollepalli, Sailalitha, Mandaviya, Pooja, Zeng, Yanni, Clarke, Toni-Kim, Walker, Rosie M, Schmoll, Vanessa, Czamara, Darina, Ruiz-Arenas, Carlos, Rezwan, Faisal I, Marioni, Riccardo E, Lin, Tian, Awaloff, Yvonne, Germain, Marine, Aïssi, Dylan, Zwamborn, Ramona, van Eijk, Kristel, Dekker, Annelot, van Dongen, Jenny, Hottenga, Jouke-Jan, Willemsen, Gonneke, Xu, Cheng-Jian, Barturen, Guillermo, Català-Moll, Francesc, Kerick, Martin, Wang, Carol, Melton, Phillip, Elliott, Hannah R, Shin, Jean, Bernard, Manon, Yet, Idil, Smart, Melissa, Gorrie-Stone, Tyler, Shaw, Chris, Al Chalabi, Ammar, Ring, Susan M, Pershagen, Göran, Melén, Erik, Jiménez-Conde, Jordi, Roquer, Jaume, Lawlor, Deborah A, Wright, John, Martin, Nicholas G, Montgomery, Grant W, Moffitt, Terrie E, Poulton, Richie, Esko, Tõnu, Milani, Lili, Metspalu, Andres, Perry, John RB, Ong, Ken K, Wareham, Nicholas J, Matullo, Giuseppe, Sacerdote, Carlotta, Panico, Salvatore, Caspi, Avshalom, Arseneault, Louise, Gagnon, France, Ollikainen, Miina, Kaprio, Jaakko, Felix, Janine F, Rivadeneira, Fernando, Tiemeier, Henning, van IJzendoorn, Marinus H, Uitterlinden, André G, Jaddoe, Vincent WV, Haley, Chris, McIntosh, Andrew M, Evans, Kathryn L, Murray, Alison, Räikkönen, Katri, Lahti, Jari, Nohr, Ellen A, Sørensen, Thorkild IA, Hansen, Torben, Morgen, Camilla S, Binder, Elisabeth B, Lucae, Susanne, Gonzalez, Juan Ramon, Bustamante, Mariona, Sunyer, Jordi, Holloway, John W, Karmaus, Wilfried, Zhang, Hongmei, Deary, Ian J, Wray, Naomi R, Starr, John M, Beekman, Marian, van Heemst, Diana, Slagboom, P Eline, Morange, Pierre-Emmanuel, Trégouët, David-Alexandre, Veldink, Jan H, Davies, Gareth E, de Geus, Eco JC, Boomsma, Dorret I, Vonk, Judith M, Brunekreef, Bert, Koppelman, Gerard H, Alarcón-Riquelme, Marta E, Huang, Rae-Chi, Pennell, Craig E, van Meurs, Joyce, Ikram, M Arfan, Hughes, Alun D, Tillin, Therese, Chaturvedi, Nish, Pausova, Zdenka, Paus, Tomas, Spector, Timothy D, Kumari, Meena, Schalkwyk, Leonard C, Visscher, Peter M, Smith, George Davey, Bock, Christoph, Gaunt, Tom R, Bell, Jordana T, Heijmans, Bastiaan T, Mill, Jonathan, Relton, Caroline L
Publicado 2021