Open Data Revolution in Clinical Research: Opportunities and Challenges

por Shahin, Mohamed H., Bhattacharya, Sanchita, Silva, Diego, Kim, Sarah, Burton, Jackson, Podichetty, Jagdeep, Romero, Klaus, Conrado, Daniela J.
Publicado 2020

Development of a model‐based clinical trial simulation platform to optimize the design of clinical trials for Duchenne muscular dystrophy

por Lingineni, Karthik, Aggarwal, Varun, Morales, Juan Francisco, Conrado, Daniela J., Corey, Diane, Vong, Camille, Burton, Jackson, Larkindale, Jane, Romero, Klaus, Schmidt, Stephan, Kim, Sarah
Publicado 2022

Standardized Data Structures in Rare Diseases: CDISC User Guides for Duchenne Muscular Dystrophy and Huntington’s Disease

por Mullin, Ariana P., Corey, Diane, Turner, Emily C., Liwski, Richard, Olson, Daniel, Burton, Jackson, Sivakumaran, Sudhir, Hudson, Lynn D., Romero, Klaus, Stephenson, Diane T., Larkindale, Jane
Publicado 2020

Leveraging Real‐World Data for EMA Qualification of a Model‐Based Biomarker Tool to Optimize Type‐1 Diabetes Prevention Studies

por Podichetty, Jagdeep T., Lang, Patrick, O’Doherty, Inish M., David, Sarah E., Muse, Rhoda N., Karpen, Stephen R., Song, Laura Sue, Romero, Klaus, Burton, Jackson K.
Publicado 2022

Machine Learning in Drug Discovery and Development Part 1: A Primer

por Talevi, Alan, Morales, Juan Francisco, Hather, Gregory, Podichetty, Jagdeep T., Kim, Sarah, Bloomingdale, Peter C., Kim, Samuel, Burton, Jackson, Brown, Joshua D., Winterstein, Almut G., Schmidt, Stephan, White, Jensen Kael, Conrado, Daniela J.
Publicado 2020

Recommendations to Optimize the Use of Volumetric MRI in Huntington's Disease Clinical Trials

por Kinnunen, Kirsi M., Mullin, Ariana P., Pustina, Dorian, Turner, Emily C., Burton, Jackson, Gordon, Mark F., Scahill, Rachael I., Gantman, Emily C., Noble, Simon, Romero, Klaus, Georgiou-Karistianis, Nellie, Schwarz, Adam J.
Publicado 2021

Disease progression joint model predicts time to type 1 diabetes onset: Optimizing future type 1 diabetes prevention studies

por Morales, Juan Francisco, Muse, Rhoda, Podichetty, Jagdeep T., Burton, Jackson, David, Sarah, Lang, Patrick, Schmidt, Stephan, Romero, Klaus, O'Doherty, Inish, Martin, Frank, Campbell‐Thompson, Martha, Haller, Michael J., Atkinson, Mark A., Kim, Sarah
Publicado 2023

Molecular Neuroimaging of the Dopamine Transporter as a Patient Enrichment Biomarker for Clinical Trials for Early Parkinson's Disease

por Romero, Klaus, Conrado, Daniela, Burton, Jackson, Nicholas, Timothy, Sinha, Vikram, Macha, Sreeraj, Ahamadi, Malidi, Cedarbaum, Jesse, Seibyl, John, Marek, Kenneth, Basseches, Peter, Hill, Derek, Somer, Ed, Gallagher, Jill, Dexter, David T., Roach, Arthur, Stephenson, Diane
Publicado 2019

Identifying and characterising sources of variability in digital outcome measures in Parkinson’s disease

por Roussos, George, Herrero, Teresa Ruiz, Hill, Derek L., Dowling, Ariel V., L. T. M. Müller, Martijn, Evers, Luc J. W., Burton, Jackson, Derungs, Adrian, Fisher, Katherine, Kilambi, Krishna Praneeth, Mehrotra, Nitin, Bhatnagar, Roopal, Sardar, Sakshi, Stephenson, Diane, Adams, Jamie L., Ray Dorsey, E., Cosman, Josh
Publicado 2022