Solution Structure and Elevator Mechanism of the Membrane Electron Transporter CcdA

por Zhou, Yunpeng, Bushweller, John H.
Publicado 2018

The PHD3 Domain of MLL Acts as a CYP33-Regulated Switch between MLL-Mediated Activation and Repression†,‡

por Park, Sangho, Osmers, Ute, Raman, Gayathree, Schwantes, Rebecca H., Diaz, Manuel O., Bushweller, John H.
Publicado 2010

On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF

por Zheng, Meiying, Cierpicki, Tomasz, Momotani, Ko, Artamonov, Mykhaylo V, Derewenda, Urszula, Bushweller, John H, Somlyo, Avril V, Derewenda, Zygmunt S
Publicado 2009

P444: SINGLE CELL RNASEQ UNCOVERING THE ROLE OF A LEUKEMIC DRIVER GENE FUSION CBFΒ::MYH11 IN THE LEUKEMIC–NICHE SIGNALING

por Derevyanko, Polina, V Dolgikh, Alexandra, Ashtiani, Minoo, Krippner-Heidenreich, Anja, Nelson, Ryan, Bushweller, John, Barbitoff, Yury, V Predeus, Alexander, Heidenreich, Olaf
Publicado 2023

Bacillus anthracis Peptidoglycan Integrity Is Disrupted by the Chemokine CXCL10 through the FtsE/X Complex

por Margulieux, Katie R., Liebov, Benjamin K., Tirumala, Venkata S. K. K. S., Singh, Arpita, Bushweller, John H., Nakamoto, Robert K., Hughes, Molly A.
Publicado 2017

TNF‐α signaling regulates RUNX1 function in endothelial cells

por Whitmore, Hannah A. B., Amarnani, Dhanesh, O'Hare, Michael, Delgado‐Tirado, Santiago, Gonzalez‐Buendia, Lucia, An, Miranda, Pedron, Julien, Bushweller, John H., Arboleda‐Velasquez, Joseph F., Kim, Leo A.
Publicado 2020

RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation

por Zhou, Nan, Gutierrez-Uzquiza, Alvaro, Zheng, Xiang Yu, Chang, Renxu, Vogl, Dan T., Garfall, Alfred L., Bernabei, Luca, Saraf, Anita, Florens, Laurence, Washburn, Michael P., Illendula, Anuradha, Bushweller, John H., Busino, Luca
Publicado 2019

Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking

por Rose, Joshua T., Moskovitz, Eliana, Boyd, Joseph R., Gordon, Jonathan A., Bouffard, Nicole A., Fritz, Andrew J., Illendula, Anuradha, Bushweller, John H., Lian, Jane B., Stein, Janet L., Zaidi, Sayyed K., Stein, Gary S.
Publicado 2020

KIX domain determines a selective tumor-promoting role for EP300 and its vulnerability in small cell lung cancer

por Kim, Kee-Beom, Kabra, Ashish, Kim, Dong-Wook, Xue, Yongming, Huang, Yuanjian, Hou, Pei-Chi, Zhou, Yunpeng, Miranda, Leilani J., Park, Jae-Il, Shi, Xiaobing, Bender, Timothy P., Bushweller, John H., Park, Kwon-Sik
Publicado 2022

Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth

por Coleman, Daniel J.L., Keane, Peter, Luque-Martin, Rosario, Chin, Paulynn S, Blair, Helen, Ames, Luke, Kellaway, Sophie G., Griffin, James, Holmes, Elizabeth, Potluri, Sandeep, Assi, Salam A., Bushweller, John, Heidenreich, Olaf, Cockerill, Peter N., Bonifer, Constanze
Publicado 2023

Regulome analysis in B-acute lymphoblastic leukemia exposes Core Binding Factor addiction as a therapeutic vulnerability

por Wray, Jason P., Deltcheva, Elitza M., Boiers, Charlotta, Richardson, Simon Е, Chhetri, Jyoti Bikram, Brown, John, Gagrica, Sladjana, Guo, Yanping, Illendula, Anuradha, Martens, Joost H. A., Stunnenberg, Hendrik G., Bushweller, John H., Nimmo, Rachael, Enver, Tariq
Publicado 2022

Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers

por Illendula, Anuradha, Gilmour, Jane, Grembecka, Jolanta, Tirumala, Venkata Sesha Srimath, Boulton, Adam, Kuntimaddi, Aravinda, Schmidt, Charles, Wang, Lixin, Pulikkan, John A., Zong, Hongliang, Parlak, Mahmut, Kuscu, Cem, Pickin, Anna, Zhou, Yunpeng, Gao, Yan, Mishra, Lauren, Adli, Mazhar, Castilla, Lucio H., Rajewski, Roger A., Janes, Kevin A., Guzman, Monica L., Bonifer, Constanze, Bushweller, John H.
Publicado 2016

Corrigendum to: “Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers” [EBioMedicine 8 (2016) 117–131]

por Illendula, Anuradha, Gilmour, Jane, Grembecka, Jolanta, Tirumala, Venkata Sesha Srimath, Boulton, Adam, Kuntimaddi, Aravinda, Schmidt, Charles, Wang, Lixin, Pulikkan, John A., Zong, Hongliang, Parlak, Mahmut, Kuscu, Cem, Pickin, Anna, Zhou, Yunpeng, Gao, Yan, Mishra, Lauren, Adli, Mazhar, Castilla, Lucio H., Rajewski, Roger A., Janes, Kevin A., Guzman, Monica L., Bonifer, Constanze, Bushweller, John H.
Publicado 2017

Targeting Runt-Related Transcription Factor 1 Prevents Pulmonary Fibrosis and Reduces Expression of Severe Acute Respiratory Syndrome Coronavirus 2 Host Mediators

por O'Hare, Michael, Amarnani, Dhanesh, Whitmore, Hannah A.B., An, Miranda, Marino, Claudia, Ramos, Leslie, Delgado-Tirado, Santiago, Hu, Xinyao, Chmielewska, Natalia, Chandrahas, Anita, Fitzek, Antonia, Heinrich, Fabian, Steurer, Stefan, Ondruschka, Benjamin, Glatzel, Markus, Krasemann, Susanne, Sepulveda-Falla, Diego, Lagares, David, Pedron, Julien, Bushweller, John H., Liu, Paul, Arboleda-Velasquez, Joseph F., Kim, Leo A.
Publicado 2021