Next-generation in situ hybridization approaches to define and quantify HIV and SIV reservoirs in tissue microenvironments

por Deleage, Claire, Chan, Chi N., Busman-Sahay, Kathleen, Estes, Jacob D.
Publicado 2018

Cis and Trans Regulatory Mechanisms Control AP2-Mediated B Cell Receptor Endocytosis via Select Tyrosine-Based Motifs

por Busman-Sahay, Kathleen, Drake, Lisa, Sitaram, Anand, Marks, Michael, Drake, James R.
Publicado 2013

Non-Human Primate Models of HIV Brain Infection and Cognitive Disorders

por Byrnes, Sarah J., Angelovich, Thomas A., Busman-Sahay, Kathleen, Cochrane, Catherine R., Roche, Michael, Estes, Jacob D., Churchill, Melissa J.
Publicado 2022

Feasibility and safety of ultrasound-guided minimally invasive autopsy in COVID-19 patients

por Brook, Olga R., Piper, Kimberly G., Mercado, Noe B., Gebre, Makda S., Barouch, Dan H., Busman-Sahay, Kathleen, Starke, Carly E., Estes, Jacob D., Martinot, Amanda J., Wrijil, Linda, Ducat, Sarah, Hecht, Jonathan L.
Publicado 2020

Ad26.COV2.S prevents upregulation of SARS-CoV-2 induced pathways of inflammation and thrombosis in hamsters and rhesus macaques

por Aid, Malika, Vidal, Samuel J., Piedra-Mora, Cesar, Ducat, Sarah, Chan, Chi N., Bondoc, Stephen, Colarusso, Alessandro, Starke, Carly E., Nekorchuk, Michael, Busman-Sahay, Kathleen, Estes, Jacob D., Martinot, Amanda J., Barouch, Dan H.
Publicado 2022

Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells

por Mudd, Joseph C., Busman-Sahay, Kathleen, DiNapoli, Sarah R., Lai, Stephen, Sheik, Virginia, Lisco, Andrea, Deleage, Claire, Richardson, Brian, Palesch, David J., Paiardini, Mirko, Cameron, Mark, Sereti, Irini, Reeves, R. Keith, Estes, Jacob D., Brenchley, Jason M.
Publicado 2018

African green monkeys avoid SIV disease progression by preventing intestinal dysfunction and maintaining mucosal barrier integrity

por Raehtz, Kevin D., Barrenäs, Fredrik, Xu, Cuiling, Busman-Sahay, Kathleen, Valentine, Audrey, Law, Lynn, Ma, Dongzhu, Policicchio, Benjamin B., Wijewardana, Viskam, Brocca-Cofano, Egidio, Trichel, Anita, Gale, Michael, Keele, Brandon F., Estes, Jacob D., Apetrei, Cristian, Pandrea, Ivona
Publicado 2020

Experimental Microbial Dysbiosis Does Not Promote Disease Progression in SIV-Infected Macaques

por Ortiz, Alexandra M., Flynn, Jacob K., DiNapoli, Sarah R., Vujkovic-Cvijin, Ivan, Starke, Carly Elizabeth C., Lai, Stephen H., Long, MacKenzie E., Sortino, Ornella, Vinton, Carol L., Mudd, Joseph C., Johnston, Leslie, Busman-Sahay, Kathleen, Belkaid, Yasmine, Estes, Jacob D., Brenchley, Jason M.
Publicado 2018

Chronic immune activation and gut barrier dysfunction is associated with neuroinflammation in ART-suppressed SIV+ rhesus macaques

por Byrnes, Sarah J., Busman-Sahay, Kathleen, Angelovich, Thomas A., Younger, Skyler, Taylor-Brill, Sol, Nekorchuk, Michael, Bondoc, Stephen, Dannay, Rachel, Terry, Margaret, Cochrane, Catherine R., Jenkins, Trisha A., Roche, Michael, Deleage, Claire, Bosinger, Steven E., Paiardini, Mirko, Brew, Bruce J., Estes, Jacob D., Churchill, Melissa J.
Publicado 2023

HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells

por Wang, Yetao, Lifshitz, Lawrence, Gellatly, Kyle, Vinton, Carol L., Busman-Sahay, Kathleen, McCauley, Sean, Vangala, Pranitha, Kim, Kyusik, Derr, Alan, Jaiswal, Smita, Kucukural, Alper, McDonel, Patrick, Hunt, Peter W., Greenough, Thomas, Houghton, JeanMarie, Somsouk, Ma, Estes, Jacob D., Brenchley, Jason M., Garber, Manuel, Deeks, Steven G., Luban, Jeremy
Publicado 2020

The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaqu...

por Webb, Gabriela M., Molden, Jhomary, Busman-Sahay, Kathleen, Abdulhaqq, Shaheed, Wu, Helen L., Weber, Whitney C., Bateman, Katherine B., Reed, Jason S., Northrup, Mina, Maier, Nicholas, Tanaka, Shiho, Gao, Lina, Davey, Brianna, Carpenter, Benjamin L., Axthelm, Michael K., Stanton, Jeffrey J., Smedley, Jeremy, Greene, Justin M., Safrit, Jeffrey T., Estes, Jacob D., Skinner, Pamela J., Sacha, Jonah B.
Publicado 2020

Rapamycin limits CD4(+) T cell proliferation in simian immunodeficiency virus–infected rhesus macaques on antiretroviral therapy

por Varco-Merth, Benjamin D., Brantley, William, Marenco, Alejandra, Duell, Derick D., Fachko, Devin N., Richardson, Brian, Busman-Sahay, Kathleen, Shao, Danica, Flores, Walter, Engelman, Kathleen, Fukazawa, Yoshinori, Wong, Scott W., Skalsky, Rebecca L., Smedley, Jeremy, Axthelm, Michael K., Lifson, Jeffrey D., Estes, Jacob D., Edlefsen, Paul T., Picker, Louis J., Cameron, Cheryl M.A., Henrich, Timothy J., Okoye, Afam A.
Publicado 2022

Correction: Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques

por Bochart, Rachele M., Busman-Sahay, Kathleen, Bondoc, Stephen, Morrow, David W., Ortiz, Alexandra M., Fennessey, Christine M., Fischer, Miranda B., Shiel, Oriene, Swanson, Tonya, Shriver-Munsch, Christine M., Crank, Hugh B., Armantrout, Kimberly M., Barber-Axthelm, Aaron M., Langner, Charlotte, Moats, Cassandra R., Labriola, Caralyn S., MacAllister, Rhonda, Axthelm, Michael K., Brenchley, Jason M., Keele, Brandon F., Estes, Jacob D., Hansen, Scott G., Smedley, Jeremy V.
Publicado 2023

TLR9 agonist MGN1703 enhances B cell differentiation and function in lymph nodes

por Schleimann, Mariane H., Kobberø, Maria-Louise, Vibholm, Line K., Kjær, Kathrine, Giron, Leila B., Busman-Sahay, Kathleen, Chan, Chi Ngai, Nekorchuk, Michael, Schmidt, Manuel, Wittig, Burghardt, Damsgaard, Tine E., Ahlburg, Peter, Hellfritzsch, Michel B., Zuwala, Kaja, Rothemejer, Frederik H., Olesen, Rikke, Schommers, Phillipp, Klein, Florian, Dweep, Harsh, Kossenkov, Andrew, Nyengaard, Jens R., Estes, Jacob D., Abdel-Mohsen, Mohamed, Østergaard, Lars, Tolstrup, Martin, Søgaard, Ole S., Denton, Paul W.
Publicado 2019

Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques

por Bochart, Rachele M., Busman-Sahay, Kathleen, Bondoc, Stephen, Morrow, David W., Ortiz, Alexandra M., Fennessey, Christine M., Fischer, Miranda B., Shiel, Oriene, Swanson, Tonya, Shriver-Munsch, Christine M., Crank, Hugh B., Armantrout, Kimberly M., Barber-Axthelm, Aaron M., Langner, Charlotte, Moats, Cassandra R., Labriola, Caralyn S., MacAllister, Rhonda, Axthelm, Michael K., Brenchley, Jason M., Keele, Brandon F., Estes, Jacob D., Hansen, Scott G., Smedley, Jeremy V.
Publicado 2021

Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy

por Harper, Justin, Ribeiro, Susan P., Chan, Chi Ngai, Aid, Malika, Deleage, Claire, Micci, Luca, Pino, Maria, Cervasi, Barbara, Raghunathan, Gopalan, Rimmer, Eric, Ayanoglu, Gulesi, Wu, Guoxin, Shenvi, Neeta, Barnard, Richard J.O., Del Prete, Gregory Q., Busman-Sahay, Kathleen, Silvestri, Guido, Kulpa, Deanna A., Bosinger, Steven E., Easley, Kirk A., Howell, Bonnie J., Gorman, Dan, Hazuda, Daria J., Estes, Jacob D., Sekaly, Rafick-Pierre, Paiardini, Mirko
Publicado 2022

Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques

por Aid, Malika, Busman-Sahay, Kathleen, Vidal, Samuel J., Maliga, Zoltan, Bondoc, Stephen, Starke, Carly, Terry, Margaret, Jacobson, Connor A., Wrijil, Linda, Ducat, Sarah, Brook, Olga R., Miller, Andrew D., Porto, Maciel, Pellegrini, Kathryn L., Pino, Maria, Hoang, Timothy N., Chandrashekar, Abishek, Patel, Shivani, Stephenson, Kathryn, Bosinger, Steven E., Andersen, Hanne, Lewis, Mark G., Hecht, Jonathan L., Sorger, Peter K., Martinot, Amanda J., Estes, Jacob D., Barouch, Dan H.
Publicado 2020

Combined protein and nucleic acid imaging reveals virus-dependent B cell and macrophage immunosuppression of tissue microenvironments

por Jiang, Sizun, Chan, Chi Ngai, Rovira-Clavé, Xavier, Chen, Han, Bai, Yunhao, Zhu, Bokai, McCaffrey, Erin, Greenwald, Noah F., Liu, Candace, Barlow, Graham L., Weirather, Jason L., Oliveria, John Paul, Nakayama, Tsuguhisa, Lee, Ivan T., Matter, Matthias S., Carlisle, Anne E., Philips, Darci, Vazquez, Gustavo, Mukherjee, Nilanjan, Busman-Sahay, Kathleen, Nekorchuk, Michael, Terry, Margaret, Younger, Skyler, Bosse, Marc, Demeter, Janos, Rodig, Scott J., Tzankov, Alexandar, Goltsev, Yury, McIlwain, David Robert, Angelo, Michael, Estes, Jacob D., Nolan, Garry P.
Publicado 2022

In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation

por Jensen, Björn-Erik Ole, Knops, Elena, Cords, Leon, Lübke, Nadine, Salgado, Maria, Busman-Sahay, Kathleen, Estes, Jacob D., Huyveneers, Laura E. P., Perdomo-Celis, Federico, Wittner, Melanie, Gálvez, Cristina, Mummert, Christiane, Passaes, Caroline, Eberhard, Johanna M., Münk, Carsten, Hauber, Ilona, Hauber, Joachim, Heger, Eva, De Clercq, Jozefien, Vandekerckhove, Linos, Bergmann, Silke, Dunay, Gábor A., Klein, Florian, Häussinger, Dieter, Fischer, Johannes C., Nachtkamp, Kathrin, Timm, Joerg, Kaiser, Rolf, Harrer, Thomas, Luedde, Tom, Nijhuis, Monique, Sáez-Cirión, Asier, Schulze zur Wiesch, Julian, Wensing, Annemarie M. J., Martinez-Picado, Javier, Kobbe, Guido
Publicado 2023

Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques

por Hoang, Timothy N., Viox, Elise G., Upadhyay, Amit A., Strongin, Zachary, Tharp, Gregory K., Pino, Maria, Nchioua, Rayhane, Hirschenberger, Maximilian, Gagne, Matthew, Nguyen, Kevin, Harper, Justin L., Marciano, Shir, Boddapati, Arun K., Pellegrini, Kathryn L., Tisoncik-Go, Jennifer, Whitmore, Leanne S., Karunakaran, Kirti A., Roy, Melissa, Kirejczyk, Shannon, Curran, Elizabeth H., Wallace, Chelsea, Wood, Jennifer S., Connor-Stroud, Fawn, Kasturi, Sudhir P., Levit, Rebecca D., Gale, Michael, Vanderford, Thomas H., Silvestri, Guido, Busman-Sahay, Kathleen, Estes, Jacob D., Vaccari, Monica, Douek, Daniel C., Sparrer, Konstantin M.J., Kirchhoff, Frank, Johnson, R. Paul, Schreiber, Gideon, Bosinger, Steven E., Paiardini, Mirko
Publicado 2022