Interplay Between the Autophagy-Lysosomal Pathway and the Ubiquitin-Proteasome System: A Target for Therapeutic Development in Alzheimer’s Disease

por Bustamante, Hianara A., González, Alexis E., Cerda-Troncoso, Cristobal, Shaughnessy, Ronan, Otth, Carola, Soza, Andrea, Burgos, Patricia V.
Publicado 2018

Turnover of C99 is Controlled by a Crosstalk between ERAD and Ubiquitin-Independent Lysosomal Degradation in Human Neuroglioma Cells

por Bustamante, Hianara A., Rivera-Dictter, Andrés, Cavieres, Viviana A., Muñoz, Vanessa C., González, Alexis, Lin, Yimo, Mardones, Gonzalo A., Burgos, Patricia V.
Publicado 2013

Tetrahydrohyperforin Inhibits the Proteolytic Processing of Amyloid Precursor Protein and Enhances Its Degradation by Atg5-Dependent Autophagy

por Cavieres, Viviana A., González, Alexis, Muñoz, Vanessa C., Yefi, Claudia P., Bustamante, Hianara A., Barraza, Rafael R., Tapia-Rojas, Cheril, Otth, Carola, Barrera, María José, González, Carlos, Mardones, Gonzalo A., Inestrosa, Nibaldo C., Burgos, Patricia V.
Publicado 2015

Negative Modulation of Macroautophagy by Stabilized HERPUD1 is Counteracted by an Increased ER-Lysosomal Network With Impact in Drug-Induced Stress Cell Survival

por Vargas, Gabriela, Cortés, Omar, Arias-Muñoz, Eloisa, Hernández, Sergio, Cerda-Troncoso, Cristobal, Hernández, Laura, González, Alexis E., Tatham, Michael H., Bustamante, Hianara A., Retamal, Claudio, Cancino, Jorge, Varas-Godoy, Manuel, Hay, Ronald T., Rojas-Fernández, Alejandro, Cavieres, Viviana A., Burgos, Patricia V.
Publicado 2022

The Proteasomal Deubiquitinating Enzyme PSMD14 Regulates Macroautophagy by Controlling Golgi-to-ER Retrograde Transport

por Bustamante, Hianara A, Cereceda, Karina, González, Alexis E, Valenzuela, Guillermo E, Cheuquemilla, Yorka, Hernández, Sergio, Arias-Muñoz, Eloisa, Cerda-Troncoso, Cristóbal, Bandau, Susanne, Soza, Andrea, Kausel, Gudrun, Kerr, Bredford, Mardones, Gonzalo A, Cancino, Jorge, Hay, Ronald T, Rojas-Fernandez, Alejandro, Burgos, Patricia V
Publicado 2020