Variant Library Annotation Tool (VaLiAnT): an oligonucleotide library design and annotation tool for saturation genome editing and other deep mutational scanning experiments

por Barbon, Luca, Offord, Victoria, Radford, Elizabeth J, Butler, Adam P, Gerety, Sebastian S, Adams, David J, Tan, Hong Kee, Waters, Andrew J
Publicado 2021

Unsupervised correction of gene-independent cell responses to CRISPR-Cas9 targeting

por Iorio, Francesco, Behan, Fiona M., Gonçalves, Emanuel, Bhosle, Shriram G., Chen, Elisabeth, Shepherd, Rebecca, Beaver, Charlotte, Ansari, Rizwan, Pooley, Rachel, Wilkinson, Piers, Harper, Sarah, Butler, Adam P., Stronach, Euan A., Saez-Rodriguez, Julio, Yusa, Kosuke, Garnett, Mathew J.
Publicado 2018

Data mining using the Catalogue of Somatic Mutations in Cancer BioMart

por Shepherd, Rebecca, Forbes, Simon A., Beare, David, Bamford, S., Cole, Charlotte G., Ward, Sari, Bindal, Nidhi, Gunasekaran, Prasad, Jia, Mingming, Kok, Chai Yin, Leung, Kenric, Menzies, Andrew, Butler, Adam P., Teague, Jon W., Campbell, Peter J., Stratton, Michael R., Futreal, P. Andrew
Publicado 2011

Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer

por Nik-Zainal, Serena, Wedge, David C., Alexandrov, Ludmil B., Petljak, Mia, Butler, Adam P., Bolli, Niccolo, Davies, Helen R., Knappskog, Stian, Martin, Sancha, Papaemmanuil, Elli, Ramakrishna, Manasa, Shlien, Adam, Simonic, Ingrid, Xue, Yali, Tyler-Smith, Chris, Campbell, Peter J., Stratton, Michael R.
Publicado 2014

Polygenic in vivo validation of cancer mutations using transposons

por Chew, Su Kit, Lu, Dong, Campos, Lia S, Scott, Kenneth L, Saci, Abdel, Wang, Juexuan, Collinson, Adam, Raine, Keiran, Hinton, Jonathan, Teague, Jon W, Jones, David, Menzies, Andrew, Butler, Adam P, Gamble, John, O’Meara, Sarah, McLaren, Stuart, Chin, Lynda, Liu, Pentao, Futreal, P Andrew
Publicado 2014

Diagnostic utility of whole genome sequencing in adults with B-other acute lymphoblastic leukemia

por Leongamornlert, Daniel, Gutiérrez-Abril, Jesús, Lee, SooWah, Barretta, Emilio, Creasey, Thomas, Gundem, Gunes, Levine, Max F., Arango-Ossa, Juan E., Liosis, Konstantinos, Medina-Martinez, Juan S., Zuborne Alapi, Krisztina, Kirkwood, Amy A., Clifton-Hadley, Laura, Patrick, Pip, Jones, David, O’Neill, Laura, Butler, Adam P., Harrison, Christine J., Campbell, Peter, Patel, Bela, Moorman, Anthony V., Fielding, Adele K., Papaemmanuil, Elli
Publicado 2023

Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups

por Bolli, Niccolo, Biancon, Giulia, Moarii, Matahi, Gimondi, Silvia, Li, Yilong, de Philippis, Chiara, Maura, Francesco, Sathiaseelan, Vijitha, Tai, Yu-Tzu, Mudie, Laura, O’Meara, Sarah, Raine, Keiran, Teague, Jon W., Butler, Adam P., Carniti, Cristiana, Gerstung, Moritz, Bagratuni, Tina, Kastritis, Efstathios, Dimopoulos, Meletios, Corradini, Paolo, Anderson, Kenneth C., Moreau, Philippe, Minvielle, Stephane, Campbell, Peter J., Papaemmanuil, Elli, Avet-Loiseau, Herve, Munshi, Nikhil C.
Publicado 2018

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

por Campbell, Peter J, Yachida, Shinichi, Mudie, Laura J, Stephens, Philip J, Pleasance, Erin D, Stebbings, Lucy A, Morsberger, Laura A, Latimer, Calli, McLaren, Stuart, Lin, Meng-Lay, McBride, David J, Varela, Ignacio, Nik-Zainal, Serena A, Leroy, Catherine, Jia, Mingming, Menzies, Andrew, Butler, Adam P, Teague, Jon W, Griffin, Constance A, Burton, John, Swerdlow, Harold, Quail, Michael A, Stratton, Michael R, Iacobuzio-Donahue, Christine, Futreal, P Andrew
Publicado 2010

The driver landscape of sporadic chordoma

por Tarpey, Patrick S., Behjati, Sam, Young, Matthew D., Martincorena, Inigo, Alexandrov, Ludmil B., Farndon, Sarah J., Guzzo, Charlotte, Hardy, Claire, Latimer, Calli, Butler, Adam P., Teague, Jon W., Shlien, Adam, Futreal, P. Andrew, Shah, Sohrab, Bashashati, Ali, Jamshidi, Farzad, Nielsen, Torsten O., Huntsman, David, Baumhoer, Daniel, Brandner, Sebastian, Wunder, Jay, Dickson, Brendan, Cogswell, Patricia, Sommer, Josh, Phillips, Joanna J., Amary, M. Fernanda, Tirabosco, Roberto, Pillay, Nischalan, Yip, Stephen, Stratton, Michael R., Flanagan, Adrienne M., Campbell, Peter J.
Publicado 2017

Mutational signatures of ionizing radiation in second malignancies

por Behjati, Sam, Gundem, Gunes, Wedge, David C., Roberts, Nicola D., Tarpey, Patrick S., Cooke, Susanna L., Van Loo, Peter, Alexandrov, Ludmil B., Ramakrishna, Manasa, Davies, Helen, Nik-Zainal, Serena, Hardy, Claire, Latimer, Calli, Raine, Keiran M., Stebbings, Lucy, Menzies, Andy, Jones, David, Shepherd, Rebecca, Butler, Adam P., Teague, Jon W., Jorgensen, Mette, Khatri, Bhavisha, Pillay, Nischalan, Shlien, Adam, Futreal, P. Andrew, Badie, Christophe, McDermott, Ultan, Bova, G. Steven, Richardson, Andrea L., Flanagan, Adrienne M., Stratton, Michael R., Campbell, Peter J.
Publicado 2016

Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma

por Behjati, Sam, Tarpey, Patrick S., Haase, Kerstin, Ye, Hongtao, Young, Matthew D., Alexandrov, Ludmil B., Farndon, Sarah J., Collord, Grace, Wedge, David C., Martincorena, Inigo, Cooke, Susanna L., Davies, Helen, Mifsud, William, Lidgren, Mathias, Martin, Sancha, Latimer, Calli, Maddison, Mark, Butler, Adam P., Teague, Jon W., Pillay, Nischalan, Shlien, Adam, McDermott, Ultan, Futreal, P. Andrew, Baumhoer, Daniel, Zaikova, Olga, Bjerkehagen, Bodil, Myklebost, Ola, Amary, M. Fernanda, Tirabosco, Roberto, Van Loo, Peter, Stratton, Michael R., Flanagan, Adrienne M., Campbell, Peter J.
Publicado 2017

Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

por Stephens, Philip J., Greenman, Chris D., Fu, Beiyuan, Yang, Fengtang, Bignell, Graham R., Mudie, Laura J., Pleasance, Erin D., Lau, King Wai, Beare, David, Stebbings, Lucy A., McLaren, Stuart, Lin, Meng-Lay, McBride, David J., Varela, Ignacio, Nik-Zainal, Serena, Leroy, Catherine, Jia, Mingming, Menzies, Andrew, Butler, Adam P., Teague, Jon W., Quail, Michael A., Burton, John, Swerdlow, Harold, Carter, Nigel P., Morsberger, Laura A., Iacobuzio-Donahue, Christine, Follows, George A., Green, Anthony R., Flanagan, Adrienne M., Stratton, Michael R., Futreal, P. Andrew, Campbell, Peter J.
Publicado 2011

Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

por Bolli, Niccolo, Avet-Loiseau, Hervé, Wedge, David C., Van Loo, Peter, Alexandrov, Ludmil B., Martincorena, Inigo, Dawson, Kevin J., Iorio, Francesco, Nik-Zainal, Serena, Bignell, Graham R., Hinton, Jonathan W., Li, Yilong, Tubio, Jose M.C., McLaren, Stuart, O' Meara, Sarah, Butler, Adam P., Teague, Jon W., Mudie, Laura, Anderson, Elizabeth, Rashid, Naim, Tai, Yu-Tzu, Shammas, Masood A., Sperling, Adam S., Fulciniti, Mariateresa, Richardson, Paul G., Parmigiani, Giovanni, Magrangeas, Florence, Minvielle, Stephane, Moreau, Philippe, Attal, Michel, Facon, Thierry, Futreal, P Andrew, Anderson, Kenneth C., Campbell, Peter J., Munshi, Nikhil C.
Publicado 2014

Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis

por Petljak, Mia, Alexandrov, Ludmil B., Brammeld, Jonathan S., Price, Stacey, Wedge, David C., Grossmann, Sebastian, Dawson, Kevin J., Ju, Young Seok, Iorio, Francesco, Tubio, Jose M.C., Koh, Ching Chiek, Georgakopoulos-Soares, Ilias, Rodríguez–Martín, Bernardo, Otlu, Burçak, O’Meara, Sarah, Butler, Adam P., Menzies, Andrew, Bhosle, Shriram G., Raine, Keiran, Jones, David R., Teague, Jon W., Beal, Kathryn, Latimer, Calli, O’Neill, Laura, Zamora, Jorge, Anderson, Elizabeth, Patel, Nikita, Maddison, Mark, Ng, Bee Ling, Graham, Jennifer, Garnett, Mathew J., McDermott, Ultan, Nik-Zainal, Serena, Campbell, Peter J., Stratton, Michael R.
Publicado 2019

Processed pseudogenes acquired somatically during cancer development

por Cooke, Susanna L., Shlien, Adam, Marshall, John, Pipinikas, Christodoulos P., Martincorena, Inigo, Tubio, Jose M.C., Li, Yilong, Menzies, Andrew, Mudie, Laura, Ramakrishna, Manasa, Yates, Lucy, Davies, Helen, Bolli, Niccolo, Bignell, Graham R., Tarpey, Patrick S., Behjati, Sam, Nik-Zainal, Serena, Papaemmanuil, Elli, Teixeira, Vitor H., Raine, Keiran, O’Meara, Sarah, Dodoran, Maryam S., Teague, Jon W., Butler, Adam P., Iacobuzio-Donahue, Christine, Santarius, Thomas, Grundy, Richard G., Malkin, David, Greaves, Mel, Munshi, Nikhil, Flanagan, Adrienne M., Bowtell, David, Martin, Sancha, Larsimont, Denis, Reis-Filho, Jorge S., Boussioutas, Alex, Taylor, Jack A., Hayes, Neil D., Janes, Sam M., Futreal, P. Andrew, Stratton, Michael R., McDermott, Ultan, Campbell, Peter J.
Publicado 2014

Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal

por Mitchell, Thomas J., Turajlic, Samra, Rowan, Andrew, Nicol, David, Farmery, James H.R., O’Brien, Tim, Martincorena, Inigo, Tarpey, Patrick, Angelopoulos, Nicos, Yates, Lucy R., Butler, Adam P., Raine, Keiran, Stewart, Grant D., Challacombe, Ben, Fernando, Archana, Lopez, Jose I., Hazell, Steve, Chandra, Ashish, Chowdhury, Simon, Rudman, Sarah, Soultati, Aspasia, Stamp, Gordon, Fotiadis, Nicos, Pickering, Lisa, Au, Lewis, Spain, Lavinia, Lynch, Joanna, Stares, Mark, Teague, Jon, Maura, Francesco, Wedge, David C., Horswell, Stuart, Chambers, Tim, Litchfield, Kevin, Xu, Hang, Stewart, Aengus, Elaidi, Reza, Oudard, Stéphane, McGranahan, Nicholas, Csabai, Istvan, Gore, Martin, Futreal, P. Andrew, Larkin, James, Lynch, Andy G., Szallasi, Zoltan, Swanton, Charles, Campbell, Peter J.
Publicado 2018

Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture

por Álvarez, Eva G., Demeulemeester, Jonas, Otero, Paula, Jolly, Clemency, García-Souto, Daniel, Pequeño-Valtierra, Ana, Zamora, Jorge, Tojo, Marta, Temes, Javier, Baez-Ortega, Adrian, Rodriguez-Martin, Bernardo, Oitaben, Ana, Bruzos, Alicia L., Martínez-Fernández, Mónica, Haase, Kerstin, Zumalave, Sonia, Abal, Rosanna, Rodríguez-Castro, Jorge, Rodriguez-Casanova, Aitor, Diaz-Lagares, Angel, Li, Yilong, Raine, Keiran M., Butler, Adam P., Otero, Iago, Ono, Atsushi, Aikata, Hiroshi, Chayama, Kazuaki, Ueno, Masaki, Hayami, Shinya, Yamaue, Hiroki, Maejima, Kazuhiro, Blanco, Miguel G., Forns, Xavier, Rivas, Carmen, Ruiz-Bañobre, Juan, Pérez-del-Pulgar, Sofía, Torres-Ruiz, Raúl, Rodriguez-Perales, Sandra, Garaigorta, Urtzi, Campbell, Peter J., Nakagawa, Hidewaki, Van Loo, Peter, Tubio, Jose M. C.
Publicado 2021

The Life History of 21 Breast Cancers

por Nik-Zainal, Serena, Van Loo, Peter, Wedge, David C., Alexandrov, Ludmil B., Greenman, Christopher D., Lau, King Wai, Raine, Keiran, Jones, David, Marshall, John, Ramakrishna, Manasa, Shlien, Adam, Cooke, Susanna L., Hinton, Jonathan, Menzies, Andrew, Stebbings, Lucy A., Leroy, Catherine, Jia, Mingming, Rance, Richard, Mudie, Laura J., Gamble, Stephen J., Stephens, Philip J., McLaren, Stuart, Tarpey, Patrick S., Papaemmanuil, Elli, Davies, Helen R., Varela, Ignacio, McBride, David J., Bignell, Graham R., Leung, Kenric, Butler, Adam P., Teague, Jon W., Martin, Sancha, Jönsson, Goran, Mariani, Odette, Boyault, Sandrine, Miron, Penelope, Fatima, Aquila, Langerød, Anita, Aparicio, Samuel A.J.R., Tutt, Andrew, Sieuwerts, Anieta M., Borg, Åke, Thomas, Gilles, Salomon, Anne Vincent, Richardson, Andrea L., Børresen-Dale, Anne-Lise, Futreal, P. Andrew, Stratton, Michael R., Campbell, Peter J.
Publicado 2012

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

por Ju, Young Seok, Alexandrov, Ludmil B, Gerstung, Moritz, Martincorena, Inigo, Nik-Zainal, Serena, Ramakrishna, Manasa, Davies, Helen R, Papaemmanuil, Elli, Gundem, Gunes, Shlien, Adam, Bolli, Niccolo, Behjati, Sam, Tarpey, Patrick S, Nangalia, Jyoti, Massie, Charles E, Butler, Adam P, Teague, Jon W, Vassiliou, George S, Green, Anthony R, Du, Ming-Qing, Unnikrishnan, Ashwin, Pimanda, John E, Teh, Bin Tean, Munshi, Nikhil, Greaves, Mel, Vyas, Paresh, El-Naggar, Adel K, Santarius, Tom, Collins, V Peter, Grundy, Richard, Taylor, Jack A, Hayes, D Neil, Malkin, David, Foster, Christopher S, Warren, Anne Y, Whitaker, Hayley C, Brewer, Daniel, Eeles, Rosalind, Cooper, Colin, Neal, David, Visakorpi, Tapio, Isaacs, William B, Bova, G Steven, Flanagan, Adrienne M, Futreal, P Andrew, Lynch, Andy G, Chinnery, Patrick F, McDermott, Ultan, Stratton, Michael R, Campbell, Peter J
Publicado 2014

Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data

por Camacho, Niedzica, Van Loo, Peter, Edwards, Sandra, Kay, Jonathan D., Matthews, Lucy, Haase, Kerstin, Clark, Jeremy, Dennis, Nening, Thomas, Sarah, Kremeyer, Barbara, Zamora, Jorge, Butler, Adam P., Gundem, Gunes, Merson, Sue, Luxton, Hayley, Hawkins, Steve, Ghori, Mohammed, Marsden, Luke, Lambert, Adam, Karaszi, Katalin, Pelvender, Gill, Massie, Charlie E., Kote-Jarai, Zsofia, Raine, Keiran, Jones, David, Howat, William J., Hazell, Steven, Livni, Naomi, Fisher, Cyril, Ogden, Christopher, Kumar, Pardeep, Thompson, Alan, Nicol, David, Mayer, Erik, Dudderidge, Tim, Yu, Yongwei, Zhang, Hongwei, Shah, Nimish C., Gnanapragasam, Vincent J., Isaacs, William, Visakorpi, Tapio, Hamdy, Freddie, Berney, Dan, Verrill, Clare, Warren, Anne Y., Wedge, David C., Lynch, Andrew G., Foster, Christopher S., Lu, Yong Jie, Bova, G. Steven, Whitaker, Hayley C., McDermott, Ultan, Neal, David E., Eeles, Rosalind, Cooper, Colin S., Brewer, Daniel S.
Publicado 2017