Pembrolizumab

por Khoja, Leila, Butler, Marcus O., Kang, S. Peter, Ebbinghaus, Scot, Joshua, Anthony M.
Publicado 2015

Mouse and Human CD1d-Self-Lipid Complexes Are Recognized Differently by Murine Invariant Natural Killer T Cell Receptors

por Guo, Tingxi, Chamoto, Kenji, Nakatsugawa, Munehide, Ochi, Toshiki, Yamashita, Yuki, Anczurowski, Mark, Butler, Marcus O., Hirano, Naoto
Publicado 2016

Patterns of response to anti-PD-1 treatment: an exploratory comparison of four radiological response criteria and associations with overall survival in metastatic melanoma patients

por Khoja, Leila, Kibiro, Minnie, Metser, Ur, Gedye, Craig, Hogg, David, Butler, Marcus O, Atenafu, Eshetu G, Joshua, Anthony M
Publicado 2016

A novel chimeric antigen receptor containing a JAK-STAT signaling domain mediates superior antitumor effects

por Kagoya, Yuki, Tanaka, Shinya, Guo, Tingxi, Anczurowski, Mark, Wang, Chung-Hsi, Saso, Kayoko, Butler, Marcus O., Minden, Mark D., Hirano, Naoto
Publicado 2018

DOT1L inhibition attenuates graft-versus-host disease by allogeneic T cells in adoptive immunotherapy models

por Kagoya, Yuki, Nakatsugawa, Munehide, Saso, Kayoko, Guo, Tingxi, Anczurowski, Mark, Wang, Chung-Hsi, Butler, Marcus O., Arrowsmith, Cheryl H., Hirano, Naoto
Publicado 2018

Real World Outcomes and Hepatotoxicity of Infliximab in the Treatment of Steroid-Refractory Immune-Related Adverse Events

por Araujo, Daniel V., Muniz, Thiago Pimentel, Yang, Anjie, Keshavarzi, Sareh, Sorotsky, Hadas, Butler, Marcus O., Saibil, Samuel, Spreafico, Anna, Hogg, David
Publicado 2021

The full blood count as a biomarker of outcome and toxicity in ipilimumab‐treated cutaneous metastatic melanoma

por Khoja, Leila, Atenafu, Eshetu G., Templeton, Arnoud, Qye, Ye, Chappell, Mary Anne, Saibil, Sam, Hogg, David, Butler, Marcus O., Joshua, Anthony M.
Publicado 2016

Mechanisms underlying the lack of endogenous processing and CLIP-mediated binding of the invariant chain by HLA-DP(84Gly)

por Anczurowski, Mark, Yamashita, Yuki, Nakatsugawa, Munehide, Ochi, Toshiki, Kagoya, Yuki, Guo, Tingxi, Wang, Chung-Hsi, Rahman, Muhammed A., Saso, Kayoko, Butler, Marcus O., Hirano, Naoto
Publicado 2018

Heterogeneity in Survival with Immune Checkpoint Inhibitors and Its Implications for Survival Extrapolations: A Case Study in Advanced Melanoma

por Federico Paly, Victoria, Kurt, Murat, Zhang, Lirong, Butler, Marcus O., Michielin, Olivier, Amadi, Adenike, Hernlund, Emma, Johnson, Helen M., Kotapati, Srividya, Moshyk, Andriy, Borrill, John
Publicado 2022

CD4(+) and CD8(+) TCRβ repertoires possess different potentials to generate extraordinarily high-avidity T cells

por Nakatsugawa, Munehide, Rahman, Muhammed A., Yamashita, Yuki, Ochi, Toshiki, Wnuk, Piotr, Tanaka, Shinya, Chamoto, Kenji, Kagoya, Yuki, Saso, Kayoko, Guo, Tingxi, Anczurowski, Mark, Butler, Marcus O., Hirano, Naoto
Publicado 2016

Analysis of the Circulating Metabolome of Patients with Cutaneous, Mucosal and Uveal Melanoma Reveals Distinct Metabolic Profiles with Implications for Response to Immunotherapy

por Vilbert, Maysa, Koch, Erica C., Rose, April A. N., Laister, Rob C., Gray, Diana, Sotov, Valentin, Penny, Susanne, Spreafico, Anna, Pinto, Devanand M., Butler, Marcus O., Saibil, Samuel D.
Publicado 2023

HLA-DP(84Gly) constitutively presents endogenous peptides generated by the class I antigen processing pathway

por Yamashita, Yuki, Anczurowski, Mark, Nakatsugawa, Munehide, Tanaka, Makito, Kagoya, Yuki, Sinha, Ankit, Chamoto, Kenji, Ochi, Toshiki, Guo, Tingxi, Saso, Kayoko, Butler, Marcus O., Minden, Mark D., Kislinger, Thomas, Hirano, Naoto
Publicado 2017

Ex Vivo Expansion of Human CD8(+) T Cells Using Autologous CD4(+) T Cell Help

por Butler, Marcus O., Imataki, Osamu, Yamashita, Yoshihiro, Tanaka, Makito, Ansén, Sascha, Berezovskaya, Alla, Metzler, Genita, Milstein, Matthew I., Mooney, Mary M., Murray, Andrew P., Mano, Hiroyuki, Nadler, Lee M., Hirano, Naoto
Publicado 2012

Immune Checkpoint Inhibitors in Advanced Cutaneous Squamous Cell Carcinoma: Real-World Experience from a Canadian Comprehensive Cancer Centre

por Koch Hein, Erica C., Vilbert, Maysa, Hirsch, Ian, Fernando Ribeiro, Mauricio, Muniz, Thiago P., Fournier, Cynthia, Abdulalem, Khaled, Saldanha, Erick F., Martinez, Erika, Spreafico, Anna, Hogg, David H., Butler, Marcus O., Saibil, Samuel D.
Publicado 2023

Biologic subtypes of melanoma predict survival benefit of combination anti-PD1+anti-CTLA4 immune checkpoint inhibitors versus anti-PD1 monotherapy

por Rose, April A N, Armstrong, Susan M, Hogg, David, Butler, Marcus O, Saibil, Samuel D, Arteaga, Diana P, Pimentel Muniz, Thiago, Kelly, Deirdre, Ghazarian, Danny, King, Ian, Kamil, Zaid Saeed, Ross, Kendra, Spreafico, Anna
Publicado 2021

PD-L1 blockade in combination with inhibition of MAPK oncogenic signaling in patients with advanced melanoma

por Ribas, Antoni, Algazi, Alain, Ascierto, Paolo A., Butler, Marcus O., Chandra, Sunandana, Gordon, Michael, Hernandez-Aya, Leonel, Lawrence, Donald, Lutzky, Jose, Miller, Wilson H., Campbell, Katie M., Delafont, Bruno, Marshall, Shannon, Mueller, Nancy, Robert, Caroline
Publicado 2020

Author Correction: PD-L1 blockade in combination with inhibition of MAPK oncogenic signaling in patients with advanced melanoma

por Ribas, Antoni, Algazi, Alain, Ascierto, Paolo A., Butler, Marcus O., Chandra, Sunandana, Gordon, Michael, Hernandez-Aya, Leonel, Lawrence, Donald, Lutzky, Jose, Miller, Wilson H., Campbell, Katie M., Delafont, Bruno, Marshall, Shannon, Mueller, Nancy, Robert, Caroline
Publicado 2021

Survival in Early Phase Immuno-Oncology Trials: Development and Validation of a Prognostic Index

por Day, Daphne, Guo, Christina, Kanjanapan, Yada, Tran, Ben, Spreafico, Anna, Joshua, Anthony M, Wang, Lisa, Abdul Razak, Albiruni R, Leighl, Natasha B, Hansen, Aaron R, Butler, Marcus O, Siu, Lillian L, Desai, Jayesh, Bedard, Philippe L
Publicado 2019

Phase I Study of Safety, Tolerability, and Efficacy of Tebentafusp Using a Step-Up Dosing Regimen and Expansion in Patients With Metastatic Uveal Melanoma

por Carvajal, Richard D., Nathan, Paul, Sacco, Joseph J., Orloff, Marlana, Hernandez-Aya, Leonel F., Yang, Jessica, Luke, Jason J., Butler, Marcus O., Stanhope, Sarah, Collins, Laura, McAlpine, Cheryl, Holland, Chris, Abdullah, Shaad E., Sato, Takami
Publicado 2022

Defining the Criteria for Reflex Testing for BRAF Mutations in Cutaneous Melanoma Patients

por Zhou, Sarah, Sikorski, Daniel, Xu, Honghao, Zubarev, Andrei, Chergui, May, Lagacé, François, Miller, Wilson H., Redpath, Margaret, Ghazal, Stephanie, Butler, Marcus O., Petrella, Teresa M., Claveau, Joël, Nessim, Carolyn, Salopek, Thomas G., Gniadecki, Robert, Litvinov, Ivan V.
Publicado 2021