Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data

por Burgess, Stephen, Butterworth, Adam, Thompson, Simon G
Publicado 2013

Beyond Mendelian randomization: how to interpret evidence of shared genetic predictors

por Burgess, Stephen, Butterworth, Adam S., Thompson, John R.
Publicado 2016

Flashfm-ivis: interactive visualization for fine-mapping of multiple quantitative traits

por Zhou, Feng, Butterworth, Adam S, Asimit, Jennifer L
Publicado 2022

An empirical investigation into the impact of winner’s curse on estimates from Mendelian randomization

por Jiang, Tao, Gill, Dipender, Butterworth, Adam S, Burgess, Stephen
Publicado 2022

Network Mendelian randomization: using genetic variants as instrumental variables to investigate mediation in causal pathways

por Burgess, Stephen, Daniel, Rhian M, Butterworth, Adam S, Thompson, Simon G
Publicado 2015

Leucocyte telomere length and risk of cardiovascular disease: systematic review and meta-analysis

por Haycock, Philip C, Heydon, Emma E, Kaptoge, Stephen, Butterworth, Adam S, Thompson, Alex, Willeit, Peter
Publicado 2014

High-throughput multivariable Mendelian randomization analysis prioritizes apolipoprotein B as key lipid risk factor for coronary artery disease

por Zuber, Verena, Gill, Dipender, Ala-Korpela, Mika, Langenberg, Claudia, Butterworth, Adam, Bottolo, Leonardo, Burgess, Stephen
Publicado 2020

A comparison of Cox and logistic regression for use in genome-wide association studies of cohort and case-cohort design

por Staley, James R, Jones, Edmund, Kaptoge, Stephen, Butterworth, Adam S, Sweeting, Michael J, Wood, Angela M, Howson, Joanna M M
Publicado 2017

PhenoScanner V2: an expanded tool for searching human genotype–phenotype associations

por Kamat, Mihir A, Blackshaw, James A, Young, Robin, Surendran, Praveen, Burgess, Stephen, Danesh, John, Butterworth, Adam S, Staley, James R
Publicado 2019

ProGeM: a framework for the prioritization of candidate causal genes at molecular quantitative trait loci

por Stacey, David, Fauman, Eric B, Ziemek, Daniel, Sun, Benjamin B, Harshfield, Eric L, Wood, Angela M, Butterworth, Adam S, Suhre, Karsten, Paul, Dirk S
Publicado 2019

Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke

por Abraham, Gad, Malik, Rainer, Yonova-Doing, Ekaterina, Salim, Agus, Wang, Tingting, Danesh, John, Butterworth, Adam S., Howson, Joanna M. M., Inouye, Michael, Dichgans, Martin
Publicado 2019

Author Correction: Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke

por Abraham, Gad, Malik, Rainer, Yonova-Doing, Ekaterina, Salim, Agus, Wang, Tingting, Danesh, John, Butterworth, Adam S., Howson, Joanna M. M., Inouye, Michael, Dichgans, Martin
Publicado 2020

Quality control and removal of technical variation of NMR metabolic biomarker data in ~120,000 UK Biobank participants

por Ritchie, Scott C., Surendran, Praveen, Karthikeyan, Savita, Lambert, Samuel A., Bolton, Thomas, Pennells, Lisa, Danesh, John, Di Angelantonio, Emanuele, Butterworth, Adam S., Inouye, Michael
Publicado 2023

Leucocyte Telomere Length and Risk of Type 2 Diabetes Mellitus: New Prospective Cohort Study and Literature-Based Meta-Analysis

por Willeit, Peter, Raschenberger, Julia, Heydon, Emma E., Tsimikas, Sotirios, Haun, Margot, Mayr, Agnes, Weger, Siegfried, Witztum, Joseph L., Butterworth, Adam S., Willeit, Johann, Kronenberg, Florian, Kiechl, Stefan
Publicado 2014

PhenoScanner: a database of human genotype–phenotype associations

por Staley, James R., Blackshaw, James, Kamat, Mihir A., Ellis, Steve, Surendran, Praveen, Sun, Benjamin B., Paul, Dirk S., Freitag, Daniel, Burgess, Stephen, Danesh, John, Young, Robin, Butterworth, Adam S.
Publicado 2016

Fibroblast Growth Factor-23 and Risk of Cardiovascular Diseases: a Mendelian Randomization study

por Donovan, Killian, Herrington, William G., Paré, Guillaume, Pigeyre, Marie, Haynes, Richard, Sardell, Rebecca, Butterworth, Adam S., Folkersen, Lasse, Gustafsson, Stefan, Wang, Qin, Baigent, Colin, Mälarstig, Anders, Holmes, Michael V., Staplin, Natalie
Publicado 2023

Machine learning optimized polygenic scores for blood cell traits identify sex-specific trajectories and genetic correlations with disease

por Xu, Yu, Vuckovic, Dragana, Ritchie, Scott C., Akbari, Parsa, Jiang, Tao, Grealey, Jason, Butterworth, Adam S., Ouwehand, Willem H., Roberts, David J., Di Angelantonio, Emanuele, Danesh, John, Soranzo, Nicole, Inouye, Michael
Publicado 2022

Risk Factors of Secondary Cardiovascular Events in a Multi-Ethnic Asian Population with Acute Myocardial Infarction: A Retrospective Cohort Study from Malaysia

por Ismail, Sophia Rasheeqa, Mohammad, Mohd Shawal Faizal, Butterworth, Adam S., Chowdhury, Rajiv, Danesh, John, Di Angelantonio, Emanuele, Griffin, Simon J., Pennells, Lisa, Wood, Angela M., Md Noh, Mohd Fairulnizal, Shah, Shamsul Azhar
Publicado 2023

The influence of rare variants in circulating metabolic biomarkers

por Riveros-Mckay, Fernando, Oliver-Williams, Clare, Karthikeyan, Savita, Walter, Klaudia, Kundu, Kousik, Ouwehand, Willem H., Roberts, David, Di Angelantonio, Emanuele, Soranzo, Nicole, Danesh, John, Wheeler, Eleanor, Zeggini, Eleftheria, Butterworth, Adam S., Barroso, Inês
Publicado 2020

Metabolic profiling of angiopoietin-like protein 3 and 4 inhibition: a drug-target Mendelian randomization analysis

por Wang, Qin, Oliver-Williams, Clare, Raitakari, Olli T, Viikari, Jorma, Lehtimäki, Terho, Kähönen, Mika, Järvelin, Marjo-Riitta, Salomaa, Veikko, Perola, Markus, Danesh, John, Kettunen, Johannes, Butterworth, Adam S, Holmes, Michael V, Ala-Korpela, Mika
Publicado 2020