Claspin haploinsufficiency leads to defects in fertility, hyperplasia and an increased oncogenic potential

por Madgwick, Suzanne, Luli, Saimir, Sellier, Helene, Butterworth, Jacqueline A., Leslie, Jack, Moore, Adam J., Corbin, Emma K., Yemm, Adrian I., Chiremba, Robson T., Tiniakos, Dina, Oakley, Fiona, Perkins, Neil D., Hunter, Jill E.
Publicado 2022

GOLT1B Activation in Hepatitis C Virus-Infected Hepatocytes Links ER Trafficking and Viral Replication

por Butterworth, Jacqueline, Gregoire, Damien, Peter, Marion, Roca Suarez, Armando Andres, Desandré, Guillaume, Simonin, Yannick, Virzì, Alessia, Zine El Aabidine, Amal, Guivarch, Marine, Andrau, Jean-Christophe, Bertrand, Edouard, Assenat, Eric, Lupberger, Joachim, Hibner, Urszula
Publicado 2021

Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance

por Hunter, Jill E., Campbell, Amy E., Butterworth, Jacqueline A., Sellier, Helene, Hannaway, Nicola L., Luli, Saimir, Floudas, Achilleas, Kenneth, Niall S., Moore, Adam J., Brownridge, Philip J., Thomas, Huw D., Coxhead, Jonathan, Taylor, Leigh, Leary, Peter, Hasoon, Megan S.R., Knight, Andrew M., Garrett, Michelle D., Collins, Ian, Eyers, Claire E., Perkins, Neil D.
Publicado 2022

Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway

por Hunter, Jill E., Campbell, Amy E., Hannaway, Nicola L., Kerridge, Scott, Luli, Saimir, Butterworth, Jacqueline A., Sellier, Helene, Mukherjee, Reshmi, Dhillon, Nikita, Sudhindar, Praveen D., Shukla, Ruchi, Brownridge, Philip J., Bell, Hayden L., Coxhead, Jonathan, Taylor, Leigh, Leary, Peter, Hasoon, Megan S.R., Collins, Ian, Garrett, Michelle D., Eyers, Claire E., Perkins, Neil D.
Publicado 2022