Claspin haploinsufficiency leads to defects in fertility, hyperplasia and an increased oncogenic potential

por Madgwick, Suzanne, Luli, Saimir, Sellier, Helene, Butterworth, Jacqueline A., Leslie, Jack, Moore, Adam J., Corbin, Emma K., Yemm, Adrian I., Chiremba, Robson T., Tiniakos, Dina, Oakley, Fiona, Perkins, Neil D., Hunter, Jill E.
Publicado 2022

Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance

por Hunter, Jill E., Campbell, Amy E., Butterworth, Jacqueline A., Sellier, Helene, Hannaway, Nicola L., Luli, Saimir, Floudas, Achilleas, Kenneth, Niall S., Moore, Adam J., Brownridge, Philip J., Thomas, Huw D., Coxhead, Jonathan, Taylor, Leigh, Leary, Peter, Hasoon, Megan S.R., Knight, Andrew M., Garrett, Michelle D., Collins, Ian, Eyers, Claire E., Perkins, Neil D.
Publicado 2022

Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway

por Hunter, Jill E., Campbell, Amy E., Hannaway, Nicola L., Kerridge, Scott, Luli, Saimir, Butterworth, Jacqueline A., Sellier, Helene, Mukherjee, Reshmi, Dhillon, Nikita, Sudhindar, Praveen D., Shukla, Ruchi, Brownridge, Philip J., Bell, Hayden L., Coxhead, Jonathan, Taylor, Leigh, Leary, Peter, Hasoon, Megan S.R., Collins, Ian, Garrett, Michelle D., Eyers, Claire E., Perkins, Neil D.
Publicado 2022