BH3 profiling and a toolkit of BH3-mimetic drugs predict anti-apoptotic dependence of cancer cells

por Butterworth, Michael, Pettitt, Andrew, Varadarajan, Shankar, Cohen, Gerald M
Publicado 2016

Acute ENaC Stimulation by cAMP in a Kidney Cell Line is Mediated by Exocytic Insertion from a Recycling Channel Pool

por Butterworth, Michael B., Edinger, Robert S., Johnson, John P., Frizzell, Raymond A.
Publicado 2005

AS160 Modulates Aldosterone-stimulated Epithelial Sodium Channel Forward Trafficking

por Liang, Xiubin, Butterworth, Michael B., Peters, Kathryn W., Frizzell, Raymond A.
Publicado 2010

Modulation of the Epithelial Sodium Channel (ENaC) by Bacterial Metalloproteases and Protease Inhibitors

por Butterworth, Michael B., Zhang, Liang, Liu, Xiaoning, Shanks, Robert M., Thibodeau, Patrick H.
Publicado 2014

The Epithelial Sodium Channel (ENaC) Establishes a Trafficking Vesicle Pool Responsible for Its Regulation

por Edinger, Robert S., Bertrand, Carol A., Rondandino, Christine, Apodaca, Gerard A., Johnson, John P., Butterworth, Michael B.
Publicado 2012

Anterograde Trafficking of KCa3.1 in Polarized Epithelia Is Rab1- and Rab8-Dependent and Recycling Endosome-Independent

por Bertuccio, Claudia A., Lee, Shih-Liang, Wu, Guangyu, Butterworth, Michael B., Hamilton, Kirk L., Devor, Daniel C.
Publicado 2014

Expression of a Diverse Array of Ca(2+)-Activated K(+) Channels (SK1/3, IK1, BK) that Functionally Couple to the Mechanosensitive TRPV4 Channel in the Collecting Duct System of Kid...

por Li, Yue, Hu, Hongxiang, Butterworth, Michael B., Tian, Jin-Bin, Zhu, Michael X., O’Neil, Roger G.
Publicado 2016

DRP-1 is required for BH3 mimetic-mediated mitochondrial fragmentation and apoptosis

por Milani, Mateus, Byrne, Dominic P, Greaves, Georgia, Butterworth, Michael, Cohen, Gerald M, Eyers, Patrick A, Varadarajan, Shankar
Publicado 2017

BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-X(L)

por Greaves, Georgia, Milani, Mateus, Butterworth, Michael, Carter, Rachel J., Byrne, Dominic P., Eyers, Patrick A., Luo, Xu, Cohen, Gerald M., Varadarajan, Shankar
Publicado 2018

Novel Modeling of Combinatorial miRNA Targeting Identifies SNP with Potential Role in Bone Density

por Coronnello, Claudia, Hartmaier, Ryan, Arora, Arshi, Huleihel, Luai, Pandit, Kusum V., Bais, Abha S., Butterworth, Michael, Kaminski, Naftali, Stormo, Gary D., Oesterreich, Steffi, Benos, Panayiotis V.
Publicado 2012

The Lhx1-Ldb1 complex interacts with Furry to regulate microRNA expression during pronephric kidney development

por Espiritu, Eugenel B., Crunk, Amanda E., Bais, Abha, Hochbaum, Daniel, Cervino, Ailen S., Phua, Yu Leng, Butterworth, Michael B., Goto, Toshiyasu, Ho, Jacqueline, Hukriede, Neil A., Cirio, M. Cecilia
Publicado 2018

Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck

por Carter, Rachel J., Milani, Mateus, Butterworth, Michael, Alotibi, Ahoud, Harper, Nicholas, Yedida, Govindaraju, Greaves, Georgia, Al-Zebeeby, Aoula, Jorgensen, Andrea L., Schache, Andrew G., Risk, Janet M., Shaw, Richard J., Jones, Terry M., Sacco, Joseph J., Hurlstone, Adam, Cohen, Gerald M., Varadarajan, Shankar
Publicado 2019