Structural insights into simocyclinone as an antibiotic, effector ligand and substrate

por Buttner, Mark J, Schäfer, Martin, Lawson, David M, Maxwell, Anthony
Publicado 2017

Multi‐layered inhibition of Streptomyces development: BldO is a dedicated repressor of whiB

por Bush, Matthew J., Chandra, Govind, Findlay, Kim C., Buttner, Mark J.
Publicado 2017

Mechanistic Basis of Branch-Site Selection in Filamentous Bacteria

por Richards, David M., Hempel, Antje M., Flärdh, Klas, Buttner, Mark J., Howard, Martin
Publicado 2012

Genes Required for Aerial Growth, Cell Division, and Chromosome Segregation Are Targets of WhiA before Sporulation in Streptomyces venezuelae

por Bush, Matthew J., Bibb, Maureen J., Chandra, Govind, Findlay, Kim C., Buttner, Mark J.
Publicado 2013

Genome-Wide Chromatin Immunoprecipitation Sequencing Analysis Shows that WhiB Is a Transcription Factor That Cocontrols Its Regulon with WhiA To Initiate Developmental Cell Divisio...

por Bush, Matthew J., Chandra, Govind, Bibb, Maureen J., Findlay, Kim C., Buttner, Mark J.
Publicado 2016

Substrate-Assisted Catalysis in Polyketide Reduction Proceeds via a Phenolate Intermediate

por Schäfer, Martin, Stevenson, Clare E.M., Wilkinson, Barrie, Lawson, David M., Buttner, Mark J.
Publicado 2016

Translational Control of the SigR-Directed Oxidative Stress Response in Streptomyces via IF3-Mediated Repression of a Noncanonical GTC Start Codon

por Feeney, Morgan A., Chandra, Govind, Findlay, Kim C., Paget, Mark S. B., Buttner, Mark J.
Publicado 2017

Phage P1-Derived Artificial Chromosomes Facilitate Heterologous Expression of the FK506 Gene Cluster

por Jones, Adam C., Gust, Bertolt, Kulik, Andreas, Heide, Lutz, Buttner, Mark J., Bibb, Mervyn J.
Publicado 2013

Determination of Phosphorylation Sites in the DivIVA Cytoskeletal Protein of Streptomyces coelicolor by Targeted LC–MS/MS

por Saalbach, Gerhard, Hempel, Antje M., Vigouroux, Marielle, Flärdh, Klas, Buttner, Mark J., Naldrett, Michael J.
Publicado 2013

Response Regulator Heterodimer Formation Controls a Key Stage in Streptomyces Development

por Al-Bassam, Mahmoud M., Bibb, Maureen J., Bush, Matthew J., Chandra, Govind, Buttner, Mark J.
Publicado 2014

BldC Delays Entry into Development To Produce a Sustained Period of Vegetative Growth in Streptomyces venezuelae

por Bush, Matthew J., Chandra, Govind, Al-Bassam, Mahmoud M., Findlay, Kim C., Buttner, Mark J.
Publicado 2019

The crystal structure of the TetR family transcriptional repressor SimR bound to DNA and the role of a flexible N-terminal extension in minor groove binding

por Le, Tung B. K., Schumacher, Maria A., Lawson, David M., Brennan, Richard G., Buttner, Mark J.
Publicado 2011

The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD(2)-(c-di-GMP)(4) complex

por Schumacher, Maria A., Zeng, Wenjie, Findlay, Kim C., Buttner, Mark J., Brennan, Richard G., Tschowri, Natalia
Publicado 2017

Interaction of the Streptomyces Wbl protein WhiD with the principal sigma factor σ(HrdB) depends on the WhiD [4Fe-4S] cluster

por Stewart, Melissa Y. Y., Bush, Matthew J., Crack, Jason C., Buttner, Mark J., Le Brun, Nick E.
Publicado 2020

Tetrameric c-di-GMP Mediates Effective Transcription Factor Dimerization to Control Streptomyces Development

por Tschowri, Natalia, Schumacher, Maria A., Schlimpert, Susan, Chinnam, Naga babu, Findlay, Kim C., Brennan, Richard G., Buttner, Mark J.
Publicado 2014

A sporulation-specific, sigF-dependent protein, SspA, affects septum positioning in Streptomyces coelicolor

por Tzanis, Angelos, Dalton, Kate A, Hesketh, Andrew, den Hengst, Chris D, Buttner, Mark J, Thibessard, Annabelle, Kelemen, Gabriella H
Publicado 2014

SimC7 Is a Novel NAD(P)H-Dependent Ketoreductase Essential for the Antibiotic Activity of the DNA Gyrase Inhibitor Simocyclinone

por Schäfer, Martin, Le, Tung B.K., Hearnshaw, Stephen J., Maxwell, Anthony, Challis, Gregory L., Wilkinson, Barrie, Buttner, Mark J.
Publicado 2015

The crystal structure of the RsbN–σ(BldN) complex from Streptomyces venezuelae defines a new structural class of anti-σ factor

por Schumacher, Maria A, Bush, Matthew J, Bibb, Maureen J, Ramos-León, Félix, Chandra, Govind, Zeng, Wenjie, Buttner, Mark J
Publicado 2018

The crystal structure of the RsbN–σ(BldN) complex from Streptomyces venezuelae defines a new structural class of anti-σ factor

por Schumacher, Maria A, Bush, Matthew J, Bibb, Maureen J, Ramos-León, Félix, Chandra, Govind, Zeng, Wenjie, Buttner, Mark J
Publicado 2018

Global Effects of the Developmental Regulator BldB in Streptomyces venezuelae

por Avramova, Marieta M., Stevenson, Clare E. M., Chandra, Govind, Holmes, Neil A., Bush, Matthew J., Findlay, Kim C., Buttner, Mark J.
Publicado 2023