Translating RNA sequencing into clinical diagnostics: opportunities and challenges

por Byron, Sara A., Van Keuren-Jensen, Kendall R., Engelthaler, David M., Carpten, John D., Craig, David W.
Publicado 2016

Identification of therapeutic targets in chordoma through comprehensive genomic and transcriptomic analyses

por Liang, Winnie S., Dardis, Christopher, Helland, Adrienne, Sekar, Shobana, Adkins, Jonathan, Cuyugan, Lori, Enriquez, Daniel, Byron, Sara, Little, Andrew S.
Publicado 2018

Sensitivity to the MEK inhibitor E6201 in melanoma cells is associated with mutant BRAF and wildtype PTEN status

por Byron, Sara A, Loch, David C, Wellens, Candice L, Wortmann, Andreas, Wu, Jiayi, Wang, John, Nomoto, Kenichi, Pollock, Pamela M
Publicado 2012

Negative Regulation of NF-κB by the ING4 Tumor Suppressor in Breast Cancer

por Byron, Sara A., Min, Elizabeth, Thal, Tanya S., Hostetter, Galen, Watanabe, Aprill T., Azorsa, David O., Little, Tanya H., Tapia, Coya, Kim, Suwon
Publicado 2012

FGFR2 Point Mutations in 466 Endometrioid Endometrial Tumors: Relationship with MSI, KRAS, PIK3CA, CTNNB1 Mutations and Clinicopathological Features

por Byron, Sara A., Gartside, Michael, Powell, Matthew A., Wellens, Candice L., Gao, Feng, Mutch, David G., Goodfellow, Paul J., Pollock, Pamela M.
Publicado 2012

Correction: FGFR2 Point Mutations in 466 Endometrioid Endometrial Tumors: Relationship with MSI, KRAS, PIK3CA, CTNNB1 Mutations and Clinicopathological Features

por Byron, Sara A., Gartside, Michael, Powell, Matthew A., Wellens, Candice L., Gao, Feng, Mutch, David G., Goodfellow, Paul J., Pollock, Pamela M.
Publicado 2012

Correlates of clinical benefit from immunotherapy and targeted therapy in metastatic renal cell carcinoma: comprehensive genomic and transcriptomic analysis

por Dizman, Nazli, Lyou, Yung, Salgia, Nicholas, Bergerot, Paulo Gustavo, Hsu, JoAnn, Enriquez, Daniel, Izatt, Tyler, Trent, Jeffrey M, Byron, Sara, Pal, Sumanta
Publicado 2020

A prospective pilot study of genome-wide exome and transcriptome profiling in patients with small cell lung cancer progressing after first-line therapy

por Weiss, Glen J., Byron, Sara A., Aldrich, Jessica, Sangal, Ashish, Barilla, Heather, Kiefer, Jeffrey A., Carpten, John D., Craig, David W., Whitsett, Timothy G.
Publicado 2017

Bcl‐2 inhibitors enhance FGFR inhibitor‐induced mitochondrial‐dependent cell death in FGFR2‐mutant endometrial cancer

por Packer, Leisl M., Stehbens, Samantha J., Bonazzi, Vanessa F., Gunter, Jennifer H., Ju, Robert J., Ward, Micheal, Gartside, Michael G., Byron, Sara A., Pollock, Pamela M.
Publicado 2019

Transcriptional profiling of GBM invasion genes identifies effective inhibitors of the LIM kinase-Cofilin pathway

por Park, Jun-Bum, Agnihotri, Sameer, Golbourn, Brian, Bertrand, Kelsey C., Luck, Amanda, Sabha, Nesrin, Smith, Christian A., Byron, Sara, Zadeh, Gelareh, Croul, Sidney, Berens, Michael, Rutka, James T.
Publicado 2014

Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer

por Becker, Marc A., Ibrahim, Yasir H., Oh, Annabell S., Fagan, Dedra H., Byron, Sara A., Sarver, Aaron L., Lee, Adrian V., Shaw, Leslie M., Fan, Cheng, Perou, Charles M., Yee, Douglas
Publicado 2016

Leveraging Spatial Variation in Tumor Purity for Improved Somatic Variant Calling of Archival Tumor Only Samples

por Halperin, Rebecca F., Liang, Winnie S., Kulkarni, Sidharth, Tassone, Erica E., Adkins, Jonathan, Enriquez, Daniel, Tran, Nhan L., Hank, Nicole C., Newell, James, Kodira, Chinnappa, Korn, Ronald, Berens, Michael E., Kim, Seungchan, Byron, Sara A.
Publicado 2019

A method to reduce ancestry related germline false positives in tumor only somatic variant calling

por Halperin, Rebecca F., Carpten, John D., Manojlovic, Zarko, Aldrich, Jessica, Keats, Jonathan, Byron, Sara, Liang, Winnie S., Russell, Megan, Enriquez, Daniel, Claasen, Ana, Cherni, Irene, Awuah, Baffour, Oppong, Joseph, Wicha, Max S., Newman, Lisa A., Jaigge, Evelyn, Kim, Seungchan, Craig, David W.
Publicado 2017

Temporospatial genomic profiling in glioblastoma identifies commonly altered core pathways underlying tumor progression

por Blomquist, Mylan R, Ensign, Shannon Fortin, D’Angelo, Fulvio, Phillips, Joanna J, Ceccarelli, Michele, Peng, Sen, Halperin, Rebecca F, Caruso, Francesca P, Garofano, Luciano, Byron, Sara A, Liang, Winnie S, Craig, David W, Carpten, John D, Prados, Michael D, Trent, Jeffrey M, Berens, Michael E, Iavarone, Antonio, Dhruv, Harshil, Tran, Nhan L
Publicado 2020

Therapeutic HDAC inhibition in hypermutant diffuse intrinsic pontine glioma

por Noll, Alyssa, Myers, Carrie, Biery, Matthew C., Meechan, Michael, Tahiri, Sophie, Rajendran, Asmitha, Berens, Michael E., Paine, Danyelle, Byron, Sara, Zhang, Jiaming, Winter, Conrad, Pakiam, Fiona, Leary, Sarah E.S., Cole, Bonnie L., Jackson, Evangeline R., Dun, Matthew D., Foster, Jessica B., Evans, Myron K., Pattwell, Siobhan S., Olson, James M., Vitanza, Nicholas A.
Publicado 2023

Upfront Biology-Guided Therapy in Diffuse Intrinsic Pontine Glioma: Therapeutic, Molecular, and Biomarker Outcomes from PNOC003

por Kline, Cassie, Jain, Payal, Kilburn, Lindsay, Bonner, Erin R., Gupta, Nalin, Crawford, John R., Banerjee, Anu, Packer, Roger J., Villanueva-Meyer, Javier, Luks, Tracy, Zhang, Yalan, Kambhampati, Madhuri, Zhang, Jie, Yadavilli, Sridevi, Zhang, Bo, Gaonkar, Krutika S., Rokita, Jo Lynne, Kraya, Adam, Kuhn, John, Liang, Winnie, Byron, Sara, Berens, Michael, Molinaro, Annette, Prados, Michael, Resnick, Adam, Waszak, Sebastian M., Nazarian, Javad, Mueller, Sabine
Publicado 2022

A pilot study of genomic‐guided induction therapy followed by immunotherapy with difluoromethylornithine maintenance for high‐risk neuroblastoma

por Kraveka, Jacqueline M., Lewis, Elizabeth C., Bergendahl, Genevieve, Ferguson, William, Oesterheld, Javier, Kim, Elizabeth, Nagulapally, Abhinav B., Dykema, Karl J., Brown, Valerie I., Roberts, William D., Mitchell, Deanna, Eslin, Don, Hanson, Derek, Isakoff, Michael S., Wada, Randal K., Harrod, Virginia L., Rawwas, Jawhar, Hanna, Gina, Hendricks, William P. D., Byron, Sara A., Snuderl, Matija, Serrano, Jonathan, Trent, Jeffrey M., Saulnier Sholler, Giselle L.
Publicado 2022

Multiscale, multimodal analysis of tumor heterogeneity in IDH1 mutant vs wild-type diffuse gliomas

por Berens, Michael E., Sood, Anup, Barnholtz-Sloan, Jill S., Graf, John F., Cho, Sanghee, Kim, Seungchan, Kiefer, Jeffrey, Byron, Sara A., Halperin, Rebecca F., Nasser, Sara, Adkins, Jonathan, Cuyugan, Lori, Devine, Karen, Ostrom, Quinn, Couce, Marta, Wolansky, Leo, McDonough, Elizabeth, Schyberg, Shannon, Dinn, Sean, Sloan, Andrew E., Prados, Michael, Phillips, Joanna J., Nelson, Sarah J., Liang, Winnie S., Al-Kofahi, Yousef, Rusu, Mirabela, Zavodszky, Maria I., Ginty, Fiona
Publicado 2019

Comparative Tumor RNA Sequencing Analysis for Difficult-to-Treat Pediatric and Young Adult Patients With Cancer

por Vaske, Olena M., Bjork, Isabel, Salama, Sofie R., Beale, Holly, Tayi Shah, Avanthi, Sanders, Lauren, Pfeil, Jacob, Lam, Du L., Learned, Katrina, Durbin, Ann, Kephart, Ellen T., Currie, Rob, Newton, Yulia, Swatloski, Teresa, McColl, Duncan, Vivian, John, Zhu, Jingchun, Lee, Alex G., Leung, Stanley G., Spillinger, Aviv, Liu, Heng-Yi, Liang, Winnie S., Byron, Sara A., Berens, Michael E., Resnick, Adam C., Lacayo, Norman, Spunt, Sheri L., Rangaswami, Arun, Huynh, Van, Torno, Lilibeth, Plant, Ashley, Kirov, Ivan, Zabokrtsky, Keri B., Rassekh, S. Rod, Deyell, Rebecca J., Laskin, Janessa, Marra, Marco A., Sender, Leonard S., Mueller, Sabine, Sweet-Cordero, E. Alejandro, Goldstein, Theodore C., Haussler, David
Publicado 2019

Identifying treatment options for BRAF(V600) wild-type metastatic melanoma: A SU2C/MRA genomics-enabled clinical trial

por LoRusso, Patricia M., Sekulic, Aleksandar, Sosman, Jeffrey A., Liang, Winnie S., Carpten, John, Craig, David W., Solit, David B., Bryce, Alan H., Kiefer, Jeffrey A., Aldrich, Jessica, Nasser, Sara, Halperin, Rebecca, Byron, Sara A., Pilat, Mary Jo, Boerner, Scott A., Durecki, Diane, Hendricks, William P. D., Enriquez, Daniel, Izatt, Tyler, Keats, Jonathan, Legendre, Christophe, Markovic, Svetomir N., Weise, Amy, Naveed, Fatima, Schmidt, Jessica, Basu, Gargi D., Sekar, Shobana, Adkins, Jonathan, Tassone, Erica, Sivaprakasam, Karthigayini, Zismann, Victoria, Calvert, Valerie S., Petricoin, Emanuel F., Fecher, Leslie Anne, Lao, Christopher, Eder, J. Paul, Vogelzang, Nicholas J., Perlmutter, Jane, Gorman, Mark, Manica, Barbara, Fox, Lisa, Schork, Nicholas, Zelterman, Daniel, DeVeaux, Michelle, Joseph, Richard W., Cowey, C. Lance, Trent, Jeffrey M.
Publicado 2021