The RNA-binding protein QKI governs a muscle-specific alternative splicing program that shapes the contractile function of cardiomyocytes

por Montañés-Agudo, Pablo, Aufiero, Simona, Schepers, Eva N, van der Made, Ingeborg, Cócera-Ortega, Lucia, Ernault, Auriane C, Richard, Stéphane, Kuster, Diederik W D, Christoffels, Vincent M, Pinto, Yigal M, Creemers, Esther E
Publicado 2023

shRNAs Targeting a Common KCNQ1 Variant Could Alleviate Long-QT1 Disease Severity by Inhibiting a Mutant Allele

por Cócera-Ortega, Lucía, Wilders, Ronald, Kamps, Selina C., Fabrizi, Benedetta, Huber, Irit, van der Made, Ingeborg, van den Bout, Anouk, de Vries, Dylan K., Gepstein, Lior, Verkerk, Arie O., Pinto, Yigal M., Tijsen, Anke J.
Publicado 2022

Human Cardiomyocyte Progenitor Cells in Co-culture with Rat Cardiomyocytes Form a Pro-arrhythmic Substrate: Evidence for Two Different Arrhythmogenic Mechanisms

por Smit, Nicoline W., Cócera Ortega, Lucia, Végh, Anna M. D., Meijborg, Veronique M. F., Smits, Anke M., Klerk, Mischa, Tijsen, Anke J. M., Tan, Hanno L., Goumans, Marie-José H. T., Boink, Gerard J. J., Coronel, Ruben
Publicado 2017

Titin Circular RNAs Create a Back-Splice Motif Essential for SRSF10 Splicing

por Tijsen, Anke J., Cócera Ortega, Lucía, Reckman, Yolan J., Zhang, Xiaolei, van der Made, Ingeborg, Aufiero, Simona, Li, Jiuru, Kamps, Selina C., van den Bout, Anouk, Devalla, Harsha D., van Spaendonck-Zwarts, Karin Y., Engelhardt, Stefan, Gepstein, Lior, Ware, James S., Pinto, Yigal M.
Publicado 2021

Toward Biological Pacing by Cellular Delivery of Hcn2/SkM1

por Végh, Anna M. D., Verkerk, Arie O., Cócera Ortega, Lucía, Wang, Jianan, Geerts, Dirk, Klerk, Mischa, Lodder, Kirsten, Nobel, Ruby, Tijsen, Anke J., Devalla, Harsha D., Christoffels, Vincent M., Medina-Ramírez, Max, Smits, Anke M., Tan, Hanno L., Wilders, Ronald, Goumans, Marie José T. H., Boink, Gerard J. J.
Publicado 2021

Cardiomyocyte Progenitor Cells as a Functional Gene Delivery Vehicle for Long-Term Biological Pacing

por Végh, Anna M. D., den Haan, A. Dénise, Cócera Ortega, Lucía, Verkerk, Arie O., Sluijter, Joost P. G., Bakker, Diane, van Amersfoorth, Shirley, van Veen, Toon A. B., Klerk, Mischa, Seppen, Jurgen, de Bakker, Jacques M. T., Christoffels, Vincent M., Geerts, Dirk, Goumans, Marie José T. H., Tan, Hanno L., Boink, Gerard J. J.
Publicado 2019