Intestinal Fructose and Glucose Metabolism in Health and Disease

por Merino, Beatriz, Fernández-Díaz, Cristina M., Cózar-Castellano, Irene, Perdomo, German
Publicado 2019

Inhibition of Fatty Acid Metabolism Reduces Human Myeloma Cells Proliferation

por Tirado-Vélez, José Manuel, Joumady, Insaf, Sáez-Benito, Ana, Cózar-Castellano, Irene, Perdomo, Germán
Publicado 2012

Evolutionary Origin of Insulin-Degrading Enzyme and Its Subcellular Localization and Secretion Mechanism: A Study in Microglial Cells

por Corraliza-Gómez, Miriam, Lillo, Concepción, Cózar-Castellano, Irene, Arranz, Eduardo, Sanchez, Diego, Ganfornina, Maria D.
Publicado 2022

Primary Cilia in Pancreatic β- and α-Cells: Time to Revisit the Role of Insulin-Degrading Enzyme

por Pablos, Marta, Casanueva-Álvarez, Elena, González-Casimiro, Carlos M., Merino, Beatriz, Perdomo, Germán, Cózar-Castellano, Irene
Publicado 2022

Leptolide Improves Insulin Resistance in Diet-Induced Obese Mice

por Villa-Pérez, Pablo, Cueto, Mercedes, Díaz-Marrero, Ana R., Lobatón, Carmen D., Moreno, Alfredo, Perdomo, Germán, Cózar-Castellano, Irene
Publicado 2017

Insulin-degrading enzyme (IDE) as a modulator of microglial phenotypes in the context of Alzheimer’s disease and brain aging

por Corraliza-Gomez, Miriam, Bermejo, Teresa, Lilue, Jingtao, Rodriguez-Iglesias, Noelia, Valero, Jorge, Cozar-Castellano, Irene, Arranz, Eduardo, Sanchez, Diego, Ganfornina, Maria Dolores
Publicado 2023

Epoxypukalide Induces Proliferation and Protects against Cytokine-Mediated Apoptosis in Primary Cultures of Pancreatic β-Cells

por López-Acosta, José Francisco, Moreno-Amador, José Luis, Jiménez-Palomares, Margarita, Díaz-Marrero, Ana R., Cueto, Mercedes, Perdomo, Germán, Cózar-Castellano, Irene
Publicado 2013

Correction: Epoxypukalide Induces Proliferation and Protects against Cytokine-Mediated Apoptosis in Primary Cultures of Pancreatic β-Cells

por López-Acosta, José Francisco, Moreno-Amador, José Luis, Jiménez-Palomares, Margarita, Díaz-Marrero, Ana R., Cueto, Mercedes, Perdomo, Germán, Cózar-Castellano, Irene
Publicado 2013

miR-126 contributes to the epigenetic signature of diabetic vascular smooth muscle and enhances antirestenosis effects of Kv1.3 blockers

por Arevalo-Martinez, Marycarmen, Cidad, Pilar, Moreno-Estar, Sara, Fernández, Mirella, Albinsson, Sebastian, Cózar-Castellano, Irene, López-López, José R., Pérez-Garcia, M. Teresa
Publicado 2021

Effects of Fasting and Feeding on Transcriptional and Posttranscriptional Regulation of Insulin-Degrading Enzyme in Mice

por González-Casimiro, Carlos M., Cámara-Torres, Patricia, Merino, Beatriz, Diez-Hermano, Sergio, Postigo-Casado, Tamara, Leissring, Malcolm A., Cózar-Castellano, Irene, Perdomo, Germán
Publicado 2021

Chloro-Furanocembranolides from Leptogorgia sp. Improve Pancreatic Beta-Cell Proliferation

por Gallardo, Amalia B., Díaz-Marrero, Ana R., de la Rosa, José M., D’Croz, Luis, Perdomo, Germán, Cózar-Castellano, Irene, Darias, José, Cueto, Mercedes
Publicado 2018

Central Proliferation and Neurogenesis Is Impaired in Type 2 Diabetes and Prediabetes Animal Models

por Ramos-Rodriguez, Juan Jose, Molina-Gil, Sara, Ortiz-Barajas, Oscar, Jimenez-Palomares, Margarita, Perdomo, German, Cozar-Castellano, Irene, Lechuga-Sancho, Alfonso Maria, Garcia-Alloza, Monica
Publicado 2014

Ghrelin's Effects on Proinflammatory Cytokine Mediated Apoptosis and Their Impact on β-Cell Functionality

por Diaz-Ganete, Antonia, Baena-Nieto, Gloria, Lomas-Romero, Isabel M., Lopez-Acosta, Jose Francisco, Cozar-Castellano, Irene, Medina, Francisco, Segundo, Carmen, Lechuga-Sancho, Alfonso M.
Publicado 2015

Lessons From the First Comprehensive Molecular Characterization of Cell Cycle Control in Rodent Insulinoma Cell Lines

por Cozar-Castellano, Irene, Harb, George, Selk, Karen, Takane, Karen, Vasavada, Rupangi, Sicari, Brian, Law, Brian, Zhang, Pili, Scott, Donald K., Fiaschi-Taesch, Nathalie, Stewart, Andrew F.
Publicado 2008

Survey of the Human Pancreatic β-Cell G1/S Proteome Reveals a Potential Therapeutic Role for Cdk-6 and Cyclin D(1) in Enhancing Human β-Cell Replication and Function In Vivo

por Fiaschi-Taesch, Nathalie, Bigatel, Todd A., Sicari, Brian, Takane, Karen K., Salim, Fatima, Velazquez-Garcia, Silvia, Harb, George, Selk, Karen, Cozar-Castellano, Irene, Stewart, Andrew F.
Publicado 2009

Induction of Human β-Cell Proliferation and Engraftment Using a Single G1/S Regulatory Molecule, cdk6

por Fiaschi-Taesch, Nathalie M., Salim, Fatimah, Kleinberger, Jeffrey, Troxell, Ronnie, Cozar-Castellano, Irene, Selk, Karen, Cherok, Edward, Takane, Karen K., Scott, Donald K., Stewart, Andrew F.
Publicado 2010

Protective effects of epoxypukalide on pancreatic β-cells and glucose metabolism in STZ-induced diabetic mice

por López-Acosta, Jose F, Villa-Pérez, Pablo, Fernández-Díaz, Cristina M, Román, Daniel de Luis, Díaz-Marrero, Ana R, Cueto, Mercedes, Perdomo, Germán, Cózar-Castellano, Irene
Publicado 2015

Modulation of Insulin Sensitivity by Insulin-Degrading Enzyme

por González-Casimiro, Carlos M., Merino, Beatriz, Casanueva-Álvarez, Elena, Postigo-Casado, Tamara, Cámara-Torres, Patricia, Fernández-Díaz, Cristina M., Leissring, Malcolm A., Cózar-Castellano, Irene, Perdomo, Germán
Publicado 2021

Hepatic insulin-degrading enzyme regulates glucose and insulin homeostasis in diet-induced obese mice

por Merino, Beatriz, Fernández-Díaz, Cristina M., Parrado-Fernández, Cristina, González-Casimiro, Carlos M., Postigo-Casado, Tamara, Lobatón, Carmen D., Leissring, Malcolm A., Cózar-Castellano, Irene, Perdomo, Germán
Publicado 2020

Insulin-degrading enzyme ablation in mouse pancreatic alpha cells triggers cell proliferation, hyperplasia and glucagon secretion dysregulation

por Merino, Beatriz, Casanueva-Álvarez, Elena, Quesada, Iván, González-Casimiro, Carlos M., Fernández-Díaz, Cristina M., Postigo-Casado, Tamara, Leissring, Malcolm A., Kaestner, Klaus H., Perdomo, Germán, Cózar-Castellano, Irene
Publicado 2022