Sensitizing human multiple myeloma cells to the proteasome inhibitor bortezomib by novel curcumin analogs

por MUJTABA, TASKEEN, KANWAR, JYOTI, WAN, SHENG BIAO, CHAN, TAK HANG, DOU, Q. PING
Publicado 2012

(−)-Epiafzelechin Protects against Ovariectomy-induced Bone Loss in Adult Mice and Modulate Osteoblastic and Osteoclastic Functions In Vitro

por Wong, Ka-Chun, Cao, Sisi, Dong, Xiaoli, Law, Man-Chun, Chan, Tak-Hang, Wong, Man-Sau
Publicado 2017

Discovery of a Flavonoid FM04 as a Potent Inhibitor to Reverse P-Glycoprotein-Mediated Drug Resistance in Xenografts and Improve Oral Bioavailability of Paclitaxel

por Kan, Jason W. Y., Yan, Clare S. W., Wong, Iris L. K., Su, Xiaochun, Liu, Zhen, Chan, Tak Hang, Chow, Larry M. C.
Publicado 2022

An In-Silico, In-Vitro and In-Vivo Combined Approach to Identify NMNATs as Potential Protein Targets of ProEGCG for Treatment of Endometriosis

por Hung, Sze Wan, Liang, Bo, Gao, Yating, Zhang, Ruizhe, Tan, Zhouyurong, Zhang, Tao, Chung, Pui Wah Jacqueline, Chan, Tak Hang, Wang, Chi Chiu
Publicado 2021

Determination of (-)-epigallocatechin-3-gallate octaacetate and its metabolites in plasma of rats for pharmacokinetic study by ultra-performance-liquid-chromatography coupled to qu...

por Chu, Kai On, Man, Gene Chi Wai, Hung, Sze Wan, Chan, Tak Hang, Lee, Wai Yip Thomas, Chan, Kwok Ping, Pang, Chi Pui, Wang, Chi Chiu
Publicado 2022

Characterization of a Potent, Selective, and Safe Inhibitor, Ac15(Az8)(2), in Reversing Multidrug Resistance Mediated by Breast Cancer Resistance Protein (BCRP/ABCG2)

por Chong, Tsz Cheung, Wong, Iris L. K., Cui, Jiahua, Law, Man Chun, Zhu, Xuezhen, Hu, Xuesen, Kan, Jason W. Y., Yan, Clare S. W., Chan, Tak Hang, Chow, Larry M. C.
Publicado 2022

In Vivo Reversal of P-Glycoprotein-Mediated Drug Resistance in a Breast Cancer Xenograft and in Leukemia Models Using a Novel, Potent, and Nontoxic Epicatechin EC31

por Sun, Wenqin, Wong, Iris L. K., Law, Helen Ka-Wai, Su, Xiaochun, Chan, Terry C. F., Sun, Gege, Yang, Xinqing, Wang, Xingkai, Chan, Tak Hang, Wan, Shengbiao, Chow, Larry M. C.
Publicado 2023

Therapeutic potential of a novel prodrug of green tea extract in induction of apoptosis via ERK/JNK and Akt signaling pathway in human endometrial cancer

por Man, Gene Chi Wai, Wang, Jianzhang, Song, Yi, Wong, Jack Ho, Zhao, Yu, Lau, Tat San, Leung, Kam Tong, Chan, Tak Hang, Wang, Huating, Kwong, Joseph, Ng, Tzi Bun, Wang, Chi Chiu
Publicado 2020

Targeting the DNA Repair Endonuclease ERCC1-XPF with Green Tea Polyphenol Epigallocatechin-3-Gallate (EGCG) and Its Prodrug to Enhance Cisplatin Efficacy in Human Cancer Cells

por Heyza, Joshua R., Arora, Sanjeevani, Zhang, Hao, Conner, Kayla L., Lei, Wen, Floyd, Ashley M., Deshmukh, Rahul R., Sarver, Jeffrey, Trabbic, Christopher J., Erhardt, Paul, Chan, Tak-Hang, Dou, Q. Ping, Patrick, Steve M.
Publicado 2018

Rational Design of Berberine-Based FtsZ Inhibitors with Broad-Spectrum Antibacterial Activity

por Sun, Ning, Chan, Fung-Yi, Lu, Yu-Jing, Neves, Marco A. C., Lui, Hok-Kiu, Wang, Yong, Chow, Ka-Yan, Chan, Kin-Fai, Yan, Siu-Cheong, Leung, Yun-Chung, Abagyan, Ruben, Chan, Tak-Hang, Wong, Kwok-Yin
Publicado 2014

Efficient Synthesis of Amine-Linked 2,4,6-Trisubstituted Pyrimidines as a New Class of Bacterial FtsZ Inhibitors

por Chan, Kin-Fai, Sun, Ning, Yan, Siu-Cheong, Wong, Iris L. K., Lui, Hok-Kiu, Cheung, Kwan-Choi, Yuan, Jian, Chan, Fung-Yi, Zheng, Zhiwei, Chan, Edward W. C., Chen, Sheng, Leung, Yun-Chung, Chan, Tak Hang, Wong, Kwok-Yin
Publicado 2017