Computational Insight into Protein Tyrosine Phosphatase 1B Inhibition: A Case Study of the Combined Ligand- and Structure-Based Approach

por Zhang, Xiangyu, Jiang, Hailun, Li, Wei, Wang, Jian, Cheng, Maosheng
Publicado 2017

Guanidine-modified albumin-MMAE conjugates with enhanced endocytosis ability

por Yi, Ce, Xie, Fei, Xu, Xin, Xiao, Dian, Zhou, Xinbo, Cheng, Maosheng
Publicado 2023

Formal total synthesis of macarpine via a Au(I)-catalyzed 6-endo-dig cycloisomerization strategy

por Fu, Jiayue, Li, Bingbing, Zhou, Zefang, Cheng, Maosheng, Yang, Lu, Liu, Yongxiang
Publicado 2022

Recent Advances in Gold(I)-Catalyzed Approaches to Three-Type Small-Molecule Scaffolds via Arylalkyne Activation

por Yang, Lu, Su, Hongwei, Sun, Yue, Zhang, Sen, Cheng, Maosheng, Liu, Yongxiang
Publicado 2022

Influence of Fatty Acid Modification on the Anticancer Activity of the Antimicrobial Peptide Figainin 1

por Han, Zhenbin, Feng, Dongmei, Wang, Wenxuan, Wang, Yue, Cheng, Maosheng, Yang, Huali, Liu, Yang
Publicado 2023

Design, Synthesis and Biological Evaluation of N,N-Substituted Amine Derivatives as Cholesteryl Ester Transfer Protein Inhibitors

por Wang, Xinran, Hao, Lijuan, Xu, Xuanqi, Li, Wei, Liu, Chunchi, Zhao, Dongmei, Cheng, Maosheng
Publicado 2017

Synthesis, Molecular Docking Analysis, and Biological Evaluations of Saccharide-Modified Sulfonamides as Carbonic Anhydrase IX Inhibitors

por Zhang, Zuopeng, Yang, Huali, Zhong, Ye, Wang, Yueqing, Wang, Jian, Cheng, Maosheng, Liu, Yang
Publicado 2021

Design, synthesis and evaluation of OA-tacrine hybrids as cholinesterase inhibitors with low neurotoxicity and hepatotoxicity against Alzheimer’s disease

por Yang, Huali, Jia, Hongwei, Deng, Minghui, Zhang, Kaicheng, Liu, Yaoyang, Liu, Yang, Cheng, Maosheng, Xiao, Wei
Publicado 2023

Design, Synthesis, and Biological Evaluation of N,N-Disubstituted-4-arylthiazole-2-methylamine Derivatives as Cholesteryl Ester Transfer Inhibitors

por Wang, Xinran, Lin, Xuehua, Xu, Xuanqi, Li, Wei, Hao, Lijuan, Liu, Chunchi, Zhao, Dongmei, Cheng, Maosheng
Publicado 2017

Suppression of the increasing level of acetylcholine-stimulated intracellular Ca(2+) in guinea pig airway smooth muscle cells by mabuterol

por SONG, XIRUI, ZHAO, CHAO, DAI, CAILING, REN, YANXIN, AN, NAN, WEN, HUIMIN, PAN, LI, CHENG, MAOSHENG, ZHANG, YUYANG
Publicado 2015

Design, Synthesis and Biological Evaluation of 6-(2,6-Dichloro-3,5-dimethoxyphenyl)-4-substituted-1H-indazoles as Potent Fibroblast Growth Factor Receptor Inhibitors

por Zhang, Zhen, Zhao, Dongmei, Dai, Yang, Cheng, Maosheng, Geng, Meiyu, Shen, Jingkang, Ma, Yuchi, Ai, Jing, Xiong, Bing
Publicado 2016

Investigation of Linarinic acid and one of its derivatives against cerebral ischemia in mice

por Wang, Yihan, Zhao, Chao, Wang, Qiujv, Wen, Huimin, Gu, Yaru, Fan, Linlin, Ma, Chao, Cheng, Maosheng, Zhang, Yuyang
Publicado 2017

Studies on asymmetric total synthesis of (−)-β-hydrastine via a chiral epoxide ring-opening cascade cyclization strategy

por Li, Jihui, Wu, Tianxiao, Song, Xinjing, Zheng, Yang, Meng, Jiaxin, Qin, Qiaohua, Liu, Yongxiang, Zhao, Dongmei, Cheng, Maosheng
Publicado 2020

Computer-aided drug design, synthesis and identification of disulfide compounds as novel and potential allosteric PAK1 inhibitors

por Huang, Hanwei, Jiang, Hailun, Zhang, Xiangyu, Li, Wei, Wang, Pengliang, Liu, Funan, Wang, Jian, Bai, Mingfeng, Cheng, Maosheng
Publicado 2018

Graphene Oxide Foam Supported Titanium(IV): Recoverable Heterogeneous Catalyst for Efficient, Selective Oxidation of Arylalkyl Sulfides to Sulfoxides Under Mild Conditions

por Wang, Qinghe, Ma, Wenxi, Tong, Qiaolin, Du, Guijie, Wang, Jian, Zhang, Meng, Jiang, Hailun, Yang, Huali, Liu, Yongxiang, Cheng, Maosheng
Publicado 2017

Discovery of 2-(4-Substituted-piperidin/piperazine-1-yl)-N-(5-cyclopropyl-1H-pyrazol-3-yl)-quinazoline-2,4-diamines as PAK4 Inhibitors with Potent A549 Cell Proliferation, Migratio...

por Wu, Tianxiao, Pang, Yu, Guo, Jing, Yin, Wenbo, Zhu, Mingyue, Hao, Chenzhou, Wang, Kai, Wang, Jian, Zhao, Dongmei, Cheng, Maosheng
Publicado 2018

Identification of flavonolignans from Silybum marianum seeds as allosteric protein tyrosine phosphatase 1B inhibitors

por Qin, Ningbo, Sasaki, Tatsunori, Li, Wei, Wang, Jian, Zhang, Xiangyu, Li, Dahong, Li, Zhanlin, Cheng, Maosheng, Hua, Huiming, Koike, Kazuo
Publicado 2018

Efficient Intestinal Digestion and On Site Tumor‐Bioactivation are the Two Important Determinants for Chylomicron‐Mediated Lymph‐Targeting Triglyceride‐Mimetic Docetaxel Oral Prodr...

por Tian, Chutong, Guo, Jingjing, Wang, Gang, Sun, Bingjun, Na, Kexin, Zhang, Xuanbo, Xu, Zhuangyan, Cheng, Maosheng, He, Zhonggui, Sun, Jin
Publicado 2019

The m(6)A Methylation-Regulated AFF4 Promotes Self-Renewal of Bladder Cancer Stem Cells

por Gao, Qian, Zheng, Jin, Ni, Zegui, Sun, Pengli, Yang, Congcong, Cheng, Maosheng, Wu, Mingqing, Zhang, Xiuhong, Yuan, Lin, Zhang, Yingyin, Li, Yang
Publicado 2020

Bmi1 Severs as a Potential Tumor-Initiating Cell Marker and Therapeutic Target in Esophageal Squamous Cell Carcinoma

por Wang, Xiaochen, Li, Kang, Cheng, Maosheng, Wang, Ganping, Han, Hui, Chen, Fangfang, Liao, Wenjing, Chen, Zhi, Chen, Jianwen, Bao, Yong, Peng, Liang, Chen, Demeng
Publicado 2020