USING A BIOLOGICAL INDICATOR TO DETECT POTENTIAL SOURCES OF CROSS-CONTAMINATION IN THE DENTAL OPERATORY

por HACKNEY, RAYMOND W., CRAWFORD, JAMES J., TULIS, JERRY J.
Publicado 1998

Safety Considerations in the Development of Hippo Pathway Inhibitors in Cancers

por Kakiuchi-Kiyota, Satoko, Schutten, Melissa M., Zhong, Yu, Crawford, James J., Dey, Anwesha
Publicado 2019

Turning the Other Cheek: Influence of the cis-Tetrafluorocyclohexyl Motif on Physicochemical and Metabolic Properties

por Wang, Yong, Lee, Wendy, Chen, Yi-Chen, Zhou, Yuhui, Plise, Emile, Migliozzi, Madyson, Crawford, James J.
Publicado 2022

Chemical space docking enables large-scale structure-based virtual screening to discover ROCK1 kinase inhibitors

por Beroza, Paul, Crawford, James J., Ganichkin, Oleg, Gendelev, Leo, Harris, Seth F., Klein, Raphael, Miu, Anh, Steinbacher, Stefan, Klingler, Franca-Maria, Lemmen, Christian
Publicado 2022

Highly efficient on-DNA amide couplings promoted by micelle forming surfactants for the synthesis of DNA encoded libraries

por Hunter, James H., Anderson, Matthew J., Castan, Isaline F. S. F., Graham, Jessica S., Salvini, Catherine L. A., Stanway-Gordon, Harriet A., Crawford, James J., Madin, Andrew, Pairaudeau, Garry, Waring, Michael J.
Publicado 2021

Fragment expansion with NUDELs – poised DNA-encoded libraries

por Salvini, Catherine L. A., Darlot, Benoit, Davison, Jack, Martin, Mathew P., Tudhope, Susan J., Turberville, Shannon, Kawamura, Akane, Noble, Martin E. M., Wedge, Stephen R., Crawford, James J., Waring, Michael J.
Publicado 2023

Rate-Determining and Rate-Limiting Steps in the Clearance and Excretion of a Potent and Selective p21-Activated Kinase Inhibitor: A Case Study of Rapid Hepatic Uptake and Slow Elim...

por Fan, Peter W., Chen, Jacob Z., Jaochico, M. Allan, La, Hank, Liu, Ning, Mulder, Teresa, Cass, Robert T., Durk, Matthew, Messick, Kirsten, Valle, Nicole, Liu, Shannon, Lee, Wendy, Crawford, James J., Rudolph, Joachim, Murray, Lesley J., Khojasteh, S. Cyrus, Wright, Matthew
Publicado 2016

Discovery of Potent and Selective Tricyclic Inhibitors of Bruton’s Tyrosine Kinase with Improved Druglike Properties

por Wang, Xiaojing, Barbosa, James, Blomgren, Peter, Bremer, Meire C., Chen, Jacob, Crawford, James J., Deng, Wei, Dong, Liming, Eigenbrot, Charles, Gallion, Steve, Hau, Jonathon, Hu, Huiyong, Johnson, Adam R., Katewa, Arna, Kropf, Jeffrey E., Lee, Seung H., Liu, Lichuan, Lubach, Joseph W., Macaluso, Jen, Maciejewski, Pat, Mitchell, Scott A., Ortwine, Daniel F., DiPaolo, Julie, Reif, Karin, Scheerens, Heleen, Schmitt, Aaron, Wong, Harvey, Xiong, Jin-Ming, Xu, Jianjun, Zhao, Zhongdong, Zhou, Fusheng, Currie, Kevin S., Young, Wendy B.
Publicado 2017

NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus

por Brightbill, Hans D., Suto, Eric, Blaquiere, Nicole, Ramamoorthi, Nandhini, Sujatha-Bhaskar, Swathi, Gogol, Emily B., Castanedo, Georgette M., Jackson, Benjamin T., Kwon, Youngsu C., Haller, Susan, Lesch, Justin, Bents, Karin, Everett, Christine, Kohli, Pawan Bir, Linge, Sandra, Christian, Laura, Barrett, Kathy, Jaochico, Allan, Berezhkovskiy, Leonid M., Fan, Peter W., Modrusan, Zora, Veliz, Kelli, Townsend, Michael J., DeVoss, Jason, Johnson, Adam R., Godemann, Robert, Lee, Wyne P., Austin, Cary D., McKenzie, Brent S., Hackney, Jason A., Crawford, James J., Staben, Steven T., Alaoui Ismaili, Moulay H., Wu, Lawren C., Ghilardi, Nico
Publicado 2018

An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance

por Hagenbeek, Thijs J., Zbieg, Jason R., Hafner, Marc, Mroue, Rana, Lacap, Jennifer A., Sodir, Nicole M., Noland, Cameron L., Afghani, Shervin, Kishore, Ayush, Bhat, Kamakoti P., Yao, Xiaosai, Schmidt, Stephen, Clausen, Saundra, Steffek, Micah, Lee, Wendy, Beroza, Paul, Martin, Scott, Lin, Eva, Fong, Rina, Di Lello, Paola, Kubala, Marta H., Yang, Michelle N.-Y., Lau, Jeffrey T., Chan, Emily, Arrazate, Alfonso, An, Le, Levy, Elizabeth, Lorenzo, Maria N., Lee, Ho-June, Pham, Trang H., Modrusan, Zora, Zang, Richard, Chen, Yi-Chen, Kabza, Michal, Ahmed, Musaddeque, Li, Jason, Chang, Matthew T., Maddalo, Danilo, Evangelista, Marie, Ye, Xin, Crawford, James J., Dey, Anwesha
Publicado 2023