Crystal structure of the capsular polysaccharide synthesizing protein CapE of Staphylococcus aureus

por Miyafusa, Takamitsu, Caaveiro, Jose M. M., Tanaka, Yoshikazu, Tanner, Martin E., Tsumoto, Kouhei
Publicado 2013

Structural basis for self-assembly of a cytolytic pore lined by protein and lipid

por Tanaka, Koji, Caaveiro, Jose M.M., Morante, Koldo, González-Mañas, Juan Manuel, Tsumoto, Kouhei
Publicado 2015

Discovery and characterization of natural tropolones as inhibitors of the antibacterial target CapF from Staphylococcus aureus

por Nakano, Koichiro, Chigira, Takeru, Miyafusa, Takamitsu, Nagatoishi, Satoru, Caaveiro, Jose M. M., Tsumoto, Kouhei
Publicado 2015

Molecular basis for thermal stability and affinity in a VHH: Contribution of the framework region and its influence in the conformation of the CDR3

por Kinoshita, Seisho, Nakakido, Makoto, Mori, Chinatsu, Kuroda, Daisuke, Caaveiro, Jose M.M., Tsumoto, Kouhei
Publicado 2022

Modulation of a conformational ensemble by a small molecule that inhibits key protein–protein interactions involved in cell adhesion

por Senoo, Akinobu, Nagatoishi, Satoru, Kuroda, Daisuke, Ito, Sho, Ueno, Go, Caaveiro, Jose M. M., Tsumoto, Kouhei
Publicado 2023

Disruption of cell adhesion by an antibody targeting the cell-adhesive intermediate (X-dimer) of human P-cadherin

por Kudo, Shota, Caaveiro, Jose M. M., Nagatoishi, Satoru, Miyafusa, Takamitsu, Matsuura, Tadashi, Sudou, Yukio, Tsumoto, Kouhei
Publicado 2017

Structural and thermodynamic basis for the recognition of the substrate-binding cleft on hen egg lysozyme by a single-domain antibody

por Akiba, Hiroki, Tamura, Hiroko, Kiyoshi, Masato, Yanaka, Saeko, Sugase, Kenji, Caaveiro, Jose M. M., Tsumoto, Kouhei
Publicado 2019

Targeting hemoglobin receptors IsdH and IsdB of Staphylococcus aureus with a single VHH antibody inhibits bacterial growth

por Valenciano-Bellido, Sandra, Caaveiro, Jose M.M., Nakakido, Makoto, Kuroda, Daisuke, Aikawa, Chihiro, Nakagawa, Ichiro, Tsumoto, Kouhei
Publicado 2023

The Isolation of New Pore-Forming Toxins from the Sea Anemone Actinia fragacea Provides Insights into the Mechanisms of Actinoporin Evolution

por Morante, Koldo, Bellomio, Augusto, Viguera, Ana Rosa, González-Mañas, Juan Manuel, Tsumoto, Kouhei, Caaveiro, Jose M. M.
Publicado 2019

New Inhibitory Effects of Cilnidipine on Microglial P2X7 Receptors and IL-1β Release: An Involvement in its Alleviating Effect on Neuropathic Pain

por Yamashita, Tomohiro, Kamikaseda, Sawako, Tanaka, Aya, Tozaki-Saitoh, Hidetoshi, Caaveiro, Jose M. M., Inoue, Kazuhide, Tsuda, Makoto
Publicado 2021

Structure and role of the linker domain of the iron surface-determinant protein IsdH in heme transportation in Staphylococcus aureus

por Valenciano-Bellido, Sandra, Caaveiro, Jose M.M., Morante, Koldo, Sushko, Tatyana, Nakakido, Makoto, Nagatoishi, Satoru, Tsumoto, Kouhei
Publicado 2022

Structural basis for binding of human IgG1 to its high-affinity human receptor FcγRI

por Kiyoshi, Masato, Caaveiro, Jose M.M., Kawai, Takeaki, Tashiro, Shinya, Ide, Teruhiko, Asaoka, Yoshiharu, Hatayama, Kouta, Tsumoto, Kouhei
Publicado 2015

Structural and Thermodynamic Basis of Epitope Binding by Neutralizing and Nonneutralizing Forms of the Anti-HIV-1 Antibody 4E10

por Rujas, Edurne, Gulzar, Naveed, Morante, Koldo, Tsumoto, Kouhei, Scott, Jamie K., Nieva, José L., Caaveiro, Jose M. M.
Publicado 2015

Structural basis for antigen recognition by methylated lysine–specific antibodies

por Ishii, Misaki, Nakakido, Makoto, Caaveiro, Jose M.M., Kuroda, Daisuke, Okumura, C.J., Maruyama, Toshiaki, Entzminger, Kevin, Tsumoto, Kouhei
Publicado 2020

Anti-InlA single-domain antibodies that inhibit the cell invasion of Listeria monocytogenes

por Yamazaki, Taichi, Nagatoishi, Satoru, Yamawaki, Tsukushi, Nozawa, Takashi, Matsunaga, Ryo, Nakakido, Makoto, Caaveiro, Jose M.M., Nakagawa, Ichiro, Tsumoto, Kouhei
Publicado 2023

Affinity Improvement of a Therapeutic Antibody by Structure-Based Computational Design: Generation of Electrostatic Interactions in the Transition State Stabilizes the Antibody-Ant...

por Kiyoshi, Masato, Caaveiro, Jose M. M., Miura, Eri, Nagatoishi, Satoru, Nakakido, Makoto, Soga, Shinji, Shirai, Hiroki, Kawabata, Shigeki, Tsumoto, Kouhei
Publicado 2014

Mechanism of dimerization and structural features of human LI-cadherin

por Yui, Anna, Caaveiro, Jose M.M., Kuroda, Daisuke, Nakakido, Makoto, Nagatoishi, Satoru, Goda, Shuichiro, Maruno, Takahiro, Uchiyama, Susumu, Tsumoto, Kouhei
Publicado 2021

Identification of a Membrane-bound Prepore Species Clarifies the Lytic Mechanism of Actinoporins

por Morante, Koldo, Bellomio, Augusto, Gil-Cartón, David, Redondo-Morata, Lorena, Sot, Jesús, Scheuring, Simon, Valle, Mikel, González-Mañas, Juan Manuel, Tsumoto, Kouhei, Caaveiro, Jose M. M.
Publicado 2016

Molecular basis for governing the morphology of type-I collagen fibrils by Osteomodulin

por Tashima, Takumi, Nagatoishi, Satoru, Caaveiro, Jose M. M., Nakakido, Makoto, Sagara, Hiroshi, Kusano-Arai, Osamu, Iwanari, Hiroko, Mimuro, Hitomi, Hamakubo, Takao, Ohnuma, Shin-ichi, Tsumoto, Kouhei
Publicado 2018

Unfolding is the driving force for mitochondrial import and degradation of the Parkinson's disease-related protein DJ-1

por Queliconi, Bruno Barros, Kojima, Waka, Kimura, Mayumi, Imai, Kenichiro, Udagawa, Chisato, Motono, Chie, Hirokawa, Takatsugu, Tashiro, Shinya, Caaveiro, Jose M. M., Tsumoto, Kouhei, Yamano, Koji, Tanaka, Keiji, Matsuda, Noriyuki
Publicado 2021