DUBs Activating the Hedgehog Signaling Pathway: A Promising Therapeutic Target in Cancer

por Bufalieri, Francesca, Lospinoso Severini, Ludovica, Caimano, Miriam, Infante, Paola, Di Marcotullio, Lucia
Publicado 2020

Drug Delivery Systems for Hedgehog Inhibitors in the Treatment of SHH-Medulloblastoma

por Caimano, Miriam, Lospinoso Severini, Ludovica, Loricchio, Elena, Infante, Paola, Di Marcotullio, Lucia
Publicado 2021

Indocyanine green clearance test in liver transplantation: defining cut-off levels for graft viability assessment during organ retrieval and for the prediction of post-transplant g...

por Coppola, Alessandro, Bianco, Giuseppe, Lai, Quirino, Marrone, Giuseppe, Caimano, Miriam, Agnes, Salvatore, Spoletini, Gabriele
Publicado 2022

The RNA-Binding Ubiquitin Ligase MEX3A Affects Glioblastoma Tumorigenesis by Inducing Ubiquitylation and Degradation of RIG-I

por Bufalieri, Francesca, Caimano, Miriam, Lospinoso Severini, Ludovica, Basili, Irene, Paglia, Francesco, Sampirisi, Luigi, Loricchio, Elena, Petroni, Marialaura, Canettieri, Gianluca, Santoro, Antonio, D’Angelo, Luca, Infante, Paola, Di Marcotullio, Lucia
Publicado 2020

A Smo/Gli Multitarget Hedgehog Pathway Inhibitor Impairs Tumor Growth

por Lospinoso Severini, Ludovica, Quaglio, Deborah, Basili, Irene, Ghirga, Francesca, Bufalieri, Francesca, Caimano, Miriam, Balducci, Silvia, Moretti, Marta, Romeo, Isabella, Loricchio, Elena, Maroder, Marella, Botta, Bruno, Mori, Mattia, Infante, Paola, Di Marcotullio, Lucia
Publicado 2019

A New Smoothened Antagonist Bearing the Purine Scaffold Shows Antitumour Activity In Vitro and In Vivo

por Zárate, Ana María, Espinosa-Bustos, Christian, Guerrero, Simón, Fierro, Angélica, Oyarzún-Ampuero, Felipe, Quest, Andrew F. G., Di Marcotullio, Lucia, Loricchio, Elena, Caimano, Miriam, Calcaterra, Andrea, González-Quiroz, Matías, Aguirre, Adam, Meléndez, Jaime, Salas, Cristian O.
Publicado 2021

Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation

por Antonucci, Laura, Di Magno, Laura, D’Amico, Davide, Manni, Simona, Serrao, Silvia Maria, Di Pastena, Fiorella, Bordone, Rosa, Yurtsever, Zuleyha Nihan, Caimano, Miriam, Petroni, Marialaura, Giorgi, Alessandra, Schininà, Maria Eugenia, Yates, John r., Di Marcotullio, Lucia, De Smaele, Enrico, Checquolo, Saula, Capalbo, Carlo, Agostinelli, Enzo, Maroder, Marella, Coni, Sonia, Canettieri, Gianluca
Publicado 2018

ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP

por Bufalieri, Francesca, Infante, Paola, Bernardi, Flavia, Caimano, Miriam, Romania, Paolo, Moretti, Marta, Lospinoso Severini, Ludovica, Talbot, Julie, Melaiu, Ombretta, Tanori, Mirella, Di Magno, Laura, Bellavia, Diana, Capalbo, Carlo, Puget, Stéphanie, De Smaele, Enrico, Canettieri, Gianluca, Guardavaccaro, Daniele, Busino, Luca, Peschiaroli, Angelo, Pazzaglia, Simonetta, Giannini, Giuseppe, Melino, Gerry, Locatelli, Franco, Gulino, Alberto, Ayrault, Olivier, Fruci, Doriana, Di Marcotullio, Lucia
Publicado 2019