Targeting the telomere and shelterin complex for cancer therapy: current views and future perspectives

por Bilsland, Alan E, Cairney, Claire J, Nicol Keith, W
Publicado 2011

Mathematical Model of a Telomerase Transcriptional Regulatory Network Developed by Cell-Based Screening: Analysis of Inhibitor Effects and Telomerase Expression Mechanisms

por Bilsland, Alan E., Stevenson, Katrina, Liu, Yu, Hoare, Stacey, Cairney, Claire J., Roffey, Jon, Keith, W. Nicol
Publicado 2014

A gene expression signature classifying telomerase and ALT immortalisation reveals an hTERT regulatory network and suggests a mesenchymal stem cell origin for ALT

por Lafferty-Whyte, Kyle, Cairney, Claire J., Will, Malcolm B., Serakinci, Nedime, Daidone, Maria-Grazia, Zaffaroni, Nadia, Bilsland, Alan, Keith, W. Nicol
Publicado 2009

Atypical chemokine receptor ACKR2 controls branching morphogenesis in the developing mammary gland

por Wilson, Gillian J., Hewit, Kay D., Pallas, Kenneth J., Cairney, Claire J., Lee, Kit M., Hansell, Christopher A., Stein, Torsten, Graham, Gerard J.
Publicado 2017

A Novel Pyrazolopyrimidine Ligand of Human PGK1 and Stress Sensor DJ1 Modulates the Shelterin Complex and Telomere Length Regulation

por Bilsland, Alan E., Liu, Yu, Turnbull, Andrew, Sumpton, David, Stevenson, Katrina, Cairney, Claire J., Boyd, Susan M., Roffey, Jon, Jenkinson, David, Keith, W. Nicol
Publicado 2019

Dynamic Telomerase Gene Suppression via Network Effects of GSK3 Inhibition

por Bilsland, Alan E., Hoare, Stacey, Stevenson, Katrina, Plumb, Jane, Gomez-Roman, Natividad, Cairney, Claire, Burns, Sharon, Lafferty-Whyte, Kyle, Roffey, Jon, Hammonds, Tim, Keith, W. Nicol
Publicado 2009

Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition

por Sadaie, Mahito, Dillon, Christian, Narita, Masashi, Young, Andrew R. J., Cairney, Claire J., Godwin, Lauren S., Torrance, Christopher J., Bennett, Dorothy C., Keith, W. Nicol, Narita, Masashi
Publicado 2015

Scoring of senescence signalling in multiple human tumour gene expression datasets, identification of a correlation between senescence score and drug toxicity in the NCI60 panel an...

por Lafferty-Whyte, Kyle, Bilsland, Alan, Cairney, Claire J, Hanley, Lorna, Jamieson, Nigel B, Zaffaroni, Nadia, Oien, Karin A, Burns, Sharon, Roffey, Jon, Boyd, Susan M, Keith, W Nicol
Publicado 2010

Identification of a Selective G1-Phase Benzimidazolone Inhibitor by a Senescence-Targeted Virtual Screen Using Artificial Neural Networks()()

por Bilsland, Alan E., Pugliese, Angelo, Liu, Yu, Revie, John, Burns, Sharon, McCormick, Carol, Cairney, Claire J., Bower, Justin, Drysdale, Martin, Narita, Masashi, Sadaie, Mahito, Keith, W. Nicol
Publicado 2015

SIAXI: Placebo-controlled, randomized, double-blind study of incobotulinumtoxinA for sialorrhea

por Jost, Wolfgang H., Friedman, Andrzej, Michel, Olaf, Oehlwein, Christian, Slawek, Jaroslaw, Bogucki, Andrzej, Ochudlo, Stanislaw, Banach, Marta, Pagan, Fernando, Flatau-Baqué, Birgit, Csikós, János, Cairney, Claire J., Blitzer, Andrew
Publicado 2019

Annexin A8 Identifies a Subpopulation of Transiently Quiescent c-Kit Positive Luminal Progenitor Cells of the Ductal Mammary Epithelium

por Iglesias, Juan Manuel, Cairney, Claire J., Ferrier, Roderick K., McDonald, Laura, Soady, Kelly, Kendrick, Howard, Pringle, Marie-Anne, Morgan, Reginald O., Martin, Finian, Smalley, Matthew J., Blyth, Karen, Stein, Torsten
Publicado 2015

A ‘synthetic-sickness’ screen for senescence re-engagement targets in mutant cancer backgrounds

por Cairney, Claire J., Godwin, Lauren S., Bilsland, Alan E., Burns, Sharon, Stevenson, Katrina H., McGarry, Lynn, Revie, John, Moore, Jon D., Wiggins, Ceri M., Collinson, Rebecca S., Mudd, Clare, Tsonou, Elpida, Sadaie, Mahito, Bennett, Dorothy C., Narita, Masashi, Torrance, Christopher J., Keith, W. Nicol
Publicado 2017